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The U.S. Food and Drug Administration on Tuesday approved the drug Entresto (sacubitril/valsartan) to treat heart failure.

FDA Approves Entresto for Heart Failure

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Medication helps reduce the rate of cardiovascular death, hospitalization
People living in 94 counties spread across the lower Mississippi Delta region

Pockets of U.S. Have Excessive Colorectal Cancer Mortality

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Areas include parts of the Mississippi Delta, Appalachia, and eastern Virginia

WHO’s Response to Ebola Slowed by Politics, Bureaucracy

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Independent, international panel says affected countries acted slowly, WHO is underfunded
Rituximab retreatment at clinical relapse is at least as cost-effective as a more intensive regimen in longstanding rheumatoid arthritis

Rituximab Retreatment at Clinical Relapse Cost-Effective in RA

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At least as cost-effective as more intensive regimen in patients with longstanding RA
The benefit of extended anticoagulation after pulmonary embolism dissipates after cessation of active therapy

Benefits of Extended Anticoagulation May Not Last

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New study suggests that oral anticoagulant meds may be needed for the very long term
A subgroup of patients with dermatitis who discontinue topical corticosteroids after long-term treatment have clinical rebounding triad manifestations

Clinical Rebounding Triad After Corticosteroid Discontinuation

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Duration and frequency of topical corticosteroid use predicts rebounding triad
The U.S. Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices has voted to issue a category B recommendation for use of two serogroup B meningococcal vaccines in patients aged 16 to 23 years for short-term disease prevention

ACIP Recommends MenB Vaccine for 16- to 23-Year-Olds

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Category B recommendation for short-term protection against meningitis for all aged 16 to 23
The American Society of Clinical Oncology has endorsed postoperative radiation therapy guidelines for endometrial cancer

ASCO Endorses ASTRO Guidelines for Endometrial Cancer

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Qualifications to guidelines include stronger statements in favor of chemotherapy in some cases
Misunderstanding of the term hypertension may impact antihypertensive medication use and adherence

Misunderstanding of Term ‘Hypertension’ May Impact Care

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Patients may think of hypertension as a psychological condition, related to too much tension
Trends in hospital deaths among HIV-infected patients show that mortality during the antiretroviral therapy era is often caused by diseases and conditions other than AIDS. The findings were published online June 30 in the Journal of Hospital Medicine.

Non-AIDS In-Hospital Deaths Up in HIV-Infected Patients

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Non-AIDS infections and cardiovascular disease are common causes of mortality in the ART era