More patients have good outcome with MIST model versus drip-and-ship model in early window within six hours of stroke
THURSDAY, Aug. 5, 2021 (HealthDay News) — For patients undergoing endovascular thrombectomy for large vessel occlusion stroke, those presenting in the early window have better outcomes with use of a Mobile Interventional Stroke Team (MIST) model of treatment, according to a study published online Aug. 5 in Stroke.
Jacob R. Morey, from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues assessed patients undergoing endovascular thrombectomy from January 2017 to February 2020. Patients presenting in early (last known well of six hours or less) and late time windows were analyzed separately. The proportion with a good outcome (modified Rankin Scale score of 0 to 2) at 90 days was examined as the primary end point.
Morey found that 226 patients were included and categorized into MIST and drip-and-ship (DS) cohorts. In the early window, 54 and 28 percent of patients in the MIST model and DS model, respectively, had a good 90-day outcome (P < 0.01). Outcomes were similar in the late window (35 versus 41 percent; P = 0.77). In the early window, the median National Institutes of Health Stroke Scale scores at discharge were 5.0 and 12.0 for the MIST and DS models, respectively (P < 0.01) compared with 5.0 and 11.0, respectively, in the late window (P = 0.11).
“Every minute is precious in treating stroke, and getting to a center that offers thrombectomy is very important,” a coauthor said in a statement. “The MIST model would address this by providing faster access to this potentially life-saving, disability-reducing procedure.”
Several authors disclosed financial ties to health care and medical device companies, including Stryker, which partly funded the study.
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