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Scientists say they have identified two new genetic variants that are associated with an increased risk of breast cancer. Their findings are published online Feb. 4 in Human Molecular Genetics.

Two Novel Genetic Variants for Breast Cancer Discovered

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London scientists say variants most strongly linked to estrogen receptor-positive disease
Patients with systolic blood pressure higher than 150 mm Hg face increased risks without aggressive drug treatment started within a month and a half

Prompt, Aggressive BP Management Encouraged

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Systolic reading of 150 should prompt immediate action to prevent poor outcomes, researchers say
Menstrual abnormalities

Chronic Fatigue Syndrome Linked With Earlier Surgical Menopause

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Menstrual abnormalities, endometriosis, pelvic pain also associated with CFS
Complication rates for fluoroscopic-guided lumbar epidural steroid injections performed by certified registered nurse anesthetists are similar to physician rates cited in the literature

Complication Rate Low for CNRA Lumbar Epidural Injections

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Rates similar to physician rates for fluoroscopic-guided LESI
Early enrollment in cardiac rehabilitation does not increase major adverse event rates among patients who recently underwent open heart surgery

Early Rehab Doesn’t Increase Adverse Events Post-CABG

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Findings in coronary artery bypass graft patients entering cardiac rehab within two weeks of discharge
For patients with acute coma

Researchers Identify Predictors of Awakening After Acute Coma

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Lesser pineal shift, reduction or no increase in pineal shift on follow-up CT up odds of awakening
Meaning-centered group psychotherapy is effective for reducing psychological distress and improving spiritual well-being in patients with advanced cancer

Meaning-Centered Group Therapy Beneficial in Advanced Cancer

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Improvements in patient quality of life, reduction in psychological distress
In a population of predominantly young

Low Adherence to Daily HIV Prophylaxis in High-Risk Women

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Products that do not require daily use may be more suitable for some women
For patients with suspected stroke

Prehospital Magnesium Sulfate Doesn’t Benefit Stroke Outcomes

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No improvement in disability outcomes at 90 days with prehospital magnesium sulfate therapy
A smartphone accessory that can detect HIV and syphilis has been developed by Columbia University researchers. The findings were published in the Feb. 4 issue of Science Translational Medicine.

Smartphone Accessory Could Help Detect HIV, Syphilis

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Low-cost accessory replicates laboratory-based blood test, researchers report