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Preliminary research in mice raises the possibility that an ultrasound-based treatment might help eliminate amyloid-β plaque in the brain. The study appears in the March 11 issue of Science Translational Medicine.

Ultrasound Tx Shows Promise in Breaking Up Amyloid Plaque

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Research in mice is preliminary, but may have potential to combat the disease
Kidneys from deceased donors that have acute injuries are frequently discarded

Damaged Kidneys May Still Be Viable in Transplant

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For reasons that are unclear, certain organs even performed better six months after transplant
For patients undergoing nonemergency cardiac surgery

Restrictive Transfusion Threshold No Better Post Cardiac Surgery

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Restrictive threshold not superior to liberal threshold for morbidity, health care costs
For patients with knee osteoarthritis

Guidelines Provided for Viscosupplementation in Knee OA

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Case vignette addresses hierarchy of treatment, starting with nonpharmacologic options
Further research is needed to understand the role of physical therapy in healing and quality of life in patients with venous leg ulcers

Evidence Lacking for PT in Patients With Venous Leg Ulcers

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Exercise strengthens calf muscles and improves ankle range of motion, but impact on QOL unclear
A psychosocial telephone counseling intervention can be beneficial for cervical cancer survivors

Psychosocial Phone Counseling Aids Cervical Cancer Survivors

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Improvements in depression; lasting improvement in gynecologic and cancer-specific concerns
For patients suspected of having hemodynamically significant coronary stenosis

Exercise Perfusion CT Imaging IDs Coronary Stenosis

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Imaging is feasible and accurate for identifying hemodynamically significant coronary stenosis
Considerable safety concerns surround use of melatonin for children with sleep disorders

Melatonin Use in Children Raises Safety Concerns

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Reproductive effects in animal models; long-term endocrine effects have not been assessed in children
For men with prostate cancer

CVD Risk Up With Androgen Deprivation Tx in Prostate Cancer

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Highest risk during first 6 months of ADT among men who had ≥2 cardiovascular events before tx
Persistent nonadopters of electronic health records tend to be older

Persistent EHR Nonadoption Could Mean Lower Payment

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Less likely to receive additional payments for managing chronic conditions/complex needs