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Aggressive, Early Disease-Modifying Therapy May Slow MS Progression

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Development of paramagnetic rim lesions tied to more rapid disability progression

Vaping Tied to Lower Cognitive Scores in College Students

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Significant interactions seen for inhalant usage patterns, including frequency and type

AAP: Pediatric Heat-Related ED Visits Increased 170 Percent Over Last Decade

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Higher heat-related ED volume seen in association with summer months with higher peak temperatures

AAP: Opioid Poisonings Increasing Among Young Children

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Most common opioid was fentanyl; four children died from fentanyl poisoning, all aged under 2 years

Global Prevalence of Congenital Heart Disease at High Altitude ~9 Percent

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However, authors note this is likely underestimated and underdiagnosed

Semaglutide Beneficial for Hidradenitis Suppurativa in Patients With Obesity

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Semaglutide added to standard treatments yields improvement in quality of life, reduction in flares

Higher Burden of Comorbidity Linked to Worse Clinical Outcomes in MS

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Presence of three or more comorbidities, two or more cardiometabolic comorbidities, one psychiatric disorder linked to evidence of disease activity

Tivozanib Has Efficacy in Advanced Renal Cell Carcinoma Post-ICI Therapy

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No benefit seen for rechallenge with nivolumab after progression in the post-immune checkpoint inhibitor setting

Adjuvant Pembrolizumab Improves Survival in Muscle-Invasive Urothelial Cancer

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Improved disease-free survival seen among patients with high-risk muscle-invasive urothelial carcinoma after radical surgery

Adjuvant Durvalumab Extends Survival in Small Cell Lung Cancer

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Significantly longer overall and progression-free survival seen among patients with limited-stage small cell lung cancer