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Adjuvant Nivolumab + Ipilimumab Lacks Efficacy for Localized RCC

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Trial did not meet primary efficacy end point of disease-free survival in patients with localized RCC at high risk for postnephrectomy relapse

Multicancer Early Detection Feasible for Outpatients

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Specificity for MCED blood test using circulating tumor DNA is 99.1 percent, and positive predictive value is about 40 percent

Model Shows Behavior Changes Could Cut CV Risk in Stage 1 HTN

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Adoption of the Dietary Approaches to Stop Hypertension diet may yield largest benefit in reducing cardiovascular events

Some Ultraprocessed Foods May Lead to Broader Consumption for Teens

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Study looks at adolescent eating behavior and its implications for modifiable hypertension risk factors

Medical Cannabis Tied to Higher Risk for New Heart Rhythm Disorders

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Findings seen for people with chronic pain; no association seen for acute coronary syndrome or heart failure

Cemiplimab Studied as Neoadjuvant Therapy for Cutaneous SCC

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In phase 2 study, about half of patients with resectable stage II to IV cutaneous squamous cell carcinoma had pathological complete response

AI Model May Detect COVID-19 Cases Using Voice Changes

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Deep learning model based on voice data from crowd-sourced audio samples uses subtle voice changes to detect COVID-19 cases

Air Pollution Increases Heart Attacks in Nonsmokers

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Findings for same-day nitric oxide levels and average levels for particulate matter in the preceding three days

Bronchodilator Does Not Improve Respiratory Symptoms for Tobacco-Exposed

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No reduction seen in respiratory symptoms for symptomatic, tobacco-exposed persons without formal diagnosis of COPD

SGLT2 Inhibitors Benefit Broad Range of Heart Failure Patients

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Risk for cardiovascular death, hospitalization for heart failure reduced regardless of left ventricular ejection fraction