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Screening should include measuring aldosterone and renin and determining the aldosterone-to-renin ratio

Benefits include lower incidence of all-cause mortality, hospitalizations

Higher protein intake may be protective against muscle loss, which is tied to less improvement in glucose homeostasis

Highest mortality rates seen among older adults, rural populations, and those in the Midwest

For postmenopausal women with overweight or obesity receiving tirzepatide, menopausal hormone therapy linked to increased weight loss

No significant interaction effects seen between genetic predisposition and sweetener intake for central precocious puberty risk

Highest mortality rates seen among older adults, rural populations, and those in the Midwest

Increased risk for consumption seen during periods of rising estradiol levels

While complications are low, they increase significantly with BMI ≥50

High triglyceride-glucose index significantly associated with faster cognitive decline in the MCI-Alzheimer disease subgroup