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ADA: Once-Daily Orforglipron Linked to Significant Weight Reduction

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Weight reduction of at least 10 percent occurred in 46 to 75 percent receiving orforglipron by week 36

ADA: Glycemic Control Up With Weekly Icodec Versus Daily Insulin Glargine

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Findings in adults with type 2 diabetes who had not previously received insulin

Continuous Meropenem No Benefit in Critically Ill Patients With Sepsis

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No improvement seen in composite of all-cause mortality and emergence of pandrug- or extensively drug-resistant bacteria

ENDO: Testosterone-Replacement Noninferior to Placebo for Cardiovascular Events

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Findings seen in middle-aged men with preexisting or high risk of cardiovascular disease and hypogonadism

Successful Intubation on First Attempt Improved With Video Laryngoscopy

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Findings seen for critically ill adults undergoing tracheal intubation

Lower Mortality Seen With Hemodiafiltration for Kidney Failure

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Risk for death from any cause reduced with hemodiafiltration versus hemodialysis among patients with kidney failure

ENDO: Cases of Gestational Diabetes Increased During Pandemic

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Progressive sociodemographic changes and gestational weight gain do not fully explain increased risk seen during the second year of the pandemic

Tranexamic Acid Does Not Up Functional Outcome After Major Trauma

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No improvement seen in favorable functional outcome at six months, but reduced risk of death at 28 days after injury

Athlete Awareness of Sudden Cardiac Arrest Low

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Furthermore, only half of athletes report receiving cardiopulmonary resuscitation training

Letermovir Noninferior for CMV Prophylaxis in Kidney Recipients

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Findings in cytomegalovirus-seronegative kidney transplant recipients who receive organ from cytomegalovirus-seropositive donors