Archives
Four Genetic Variants ID’d for Risk for Progressive Multifocal Leukoencephalopathy
All four risk variants were predicted to be deleterious and were located in two immune pathways
Respiratory Infections in Childhood Increased With Urbanized Living at Birth
Environmental factors, including breastfeeding and visible damp, are associated with risk for infections
Sputum Purulence Can Predict Outcomes in Bronchiectasis
Patients with more purulent sputum experience more exacerbations and more severe exacerbations
Air Pollution Exposure Tied to Smaller Babies at Birth
However, living in a greener area could help counteract this effect
Head Injury Linked to Increase in Incident Ischemic Stroke
Dose-response association seen for risk for stroke with number of head injuries, but no association seen for severity
Reproductive Factors Linked to Risk for Lung Cancer
Early menarche, early menopause, shortened reproductive life span linked to increased risk, especially for NSCLC
Lorundrostat Effective for Lowering BP in Uncontrolled Hypertension
Changes in office systolic BP of −14.1, −13.2, −6.9, and −4.1 mm Hg seen with 100, 50, 12.5 mg once daily of lorundrostat and placebo
Intensity-Modulated Radiation Therapy Best for Locally Advanced NSCLC
Intensity-modulated radiation therapy spares more normal tissue than 3D-conformal radiotherapy
Seasonal Difference Observed in Systolic Blood Pressure
Seasonal variation of 1.4 mm Hg tied to nearly 5 percent variation in blood pressure control
Hypertension While Lying Down Tied to Worse Cardiovascular Disease Outcomes
Findings seen regardless of whether hypertension persists in seated position
