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Small, but significant reduction seen in prostate cancer deaths, but no reduction seen in all-cause mortality

Signature resulting from combining cell-free-miRNAs, exosomal-miRNAs distinguished patients with PDAC from healthy donors

Lower risk for clinically relevant bleeding seen in acute coronary syndrome, with no increase in risk for MACCE

Lower risks for first heart failure hospitalization, total heart failure hospitalization seen with empagliflozin

Lower incidence of excessive opioid consumption seen for patients receiving femoral nerve block versus adductor canal block

Lowest pain scores at 12 hours after surgery seen with continuous nerve block; very low pain scores also seen at 24, 48 hours

Higher baseline Digital AS Severity index associated with faster progression in aortic valve velocity

Fewer than half of cancer drugs granted accelerated approval demonstrate clinical benefit

Improved overall survival, progression-free survival seen, including among patients with low PD-L1 expression

Authors say sharp increase in cardiovascular risk warrants more regular screening