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An antibody fragment

Idarucizumab Deemed Effective for Dabigatran Reversal

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Findings among patients with serious bleeding or who require an urgent procedure
Comprehensive computed tomography screening in addition to a limited occult-cancer screening offers no benefit over limited screening alone for patients with a first unprovoked venous thromboembolism. The finding was published online June 22 in the New England Journal of Medicine to coincide with the International Society on Thrombosis and Haemostasis 2015 Congress

No Clinical Benefit Found for Occult Cancer CT Screening in VTE

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Prevalence of occult cancer low among patients with first unprovoked venous thromboembolism
Forgoing bridging anticoagulation therapy is noninferior to bridging with low-molecular-weight heparin in patients with atrial fibrillation undergoing an elective operation or invasive procedure. The finding was published online June 22 in the New England Journal of Medicine to coincide with the International Society on Thrombosis and Haemostasis 2015 Congress

Forgoing Bridging Anticoagulation Noninferior in A-Fib

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Findings in patients with atrial fibrillation undergoing elective operation, invasive procedure
Many people with migraines

Many Migraine Sufferers Given Ineffective, Addictive Meds

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Opioids a poor choice, especially for children, doctors say
Results from phase II clinical trials indicate that a new class of drugs

New Class of Migraine Meds Shows Promise for Prevention

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Injectable medications appear promising in early trials, but more research needed
Despite the availability of medications proven to ease migraines in children

Many Youth With Migraine May Be Missing Out on Right Rx

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Nearly half don't get any pain medications at all, researcher adds
For adult patients with vulvar lichen sclerosus

Topical Steroids Can Change Course of Vulvar Lichen Sclerosus

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Individualized preventive TCS regimen beneficial, especially for treatment compliant patients
Breast cancer patients who had poor sleep and frequent snoring before their cancer diagnosis appear to have lower survival rates

Sleep Duration Deemed Important in Breast CA Survival

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Poor sleep, snoring before diagnosis tied to poor outcomes
For patients with diabetes and cardiovascular disease

ADA: Sitagliptin Shows No Major Adverse CV Effects in T2DM, CVD

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Findings among patients with type 2 diabetes and established cardiovascular disease
Researchers are launching a clinical trial to investigate whether repeated injections of the tuberculosis vaccine bacille Calmette-Guérin (or BCG vaccine) holds promise as a treatment for type 1 diabetes. The researchers announced the start of their phase II trial Sunday at the annual meeting of the American Diabetes Association

ADA: Trial Underway for BCG Vaccine in T1DM

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Researchers will look at effects in people with longstanding disease