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Dupilumab Tied to Fewer Exacerbations in COPD With Type 2 Inflammation

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Increase seen in prebronchodilator forced expiratory volume in one second with dupilumab versus placebo at weeks 12, 52

Semaglutide Has Lasting Benefit for Weight Loss

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Second study shows cardiovascular benefit for semaglutide, regardless of weight loss

Survival Benefit for Cancer Trial Participants Does Not Persist in Adjusted Analyses

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Survival benefits disappear when only high-quality studies are pooled and with adjustment for potential publication bias

Social Determinants of Health Impact Poststroke Mortality Risk

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Strongest associations seen for educational and income attainment

Fezolinetant Safe, Effective for Moderate-to-Severe Menopause Hot Flashes

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Benefits seen within days for both frequency and severity of symptoms

Arm Fat May Predict Spinal Fracture Risk

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Higher fat mass in the arms tied to lower bone quality measured by trabecular bone score

Prehospital Reduction in BP Does Not Improve Stroke Outcomes

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Findings seen in patients with suspected acute stroke with elevated systolic blood pressure

Individuals With BAP1 Have High Rate of Nail Abnormalities

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Almost all patients with nail involvement had polydactylous involvement with onychopapillomas

Bisoprolol Does Not Reduce Exacerbations in At-Risk COPD Patients

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No reduction seen in number of self-reported exacerbations treated with oral corticosteroids, antibiotics, or both

Male, Female V1421 Carriers Face Similar Risk for Heart Failure Hospitalization

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Carriers face similar and substantial risk for heart failure hospitalization, mainly with reduced ejection fraction