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SABCS: Imlunestrant Tied to Improved PFS for ER-Positive, HER2-Negative Breast Cancer With ESR1 Mutations

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Imlunestrant leads to significantly longer progression-free survival among those with ESR1 mutations, but not in overall population

ASH: Blinatumomab + Chemo Aids Survival in B-Cell Acute Lymphoblastic Leukemia

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Estimated disease-free survival 97.5 ± 1.3 and 90.2 ± 2.3 percent with chemotherapy plus blinatumomab, chemo alone in average-risk patients

Minimally Invasive Lumbar Decompression Alleviates Pain From Lumbar Spinal Stenosis

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Mild procedure also improves physical function through one year of follow-up

RSNA: Opportunistic Assessment of Aortic Calcium Predicts MACE

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Aortic artery calcification correlates with coronary artery calcium and is associated with incident major adverse cardiovascular events

ASH: Reduced-Dose Anticoagulants Not Noninferior for Recurrent VTE

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Noninferiority of reduced-dose anticoagulants could not be proven in patients with VTE who need extended anticoagulation

ASH: Auto-HCT Not Beneficial for Mantle Cell Lymphoma With Undetectable Residual Disease

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Overall survival no better for those receiving autologous HCT plus maintenance rituximab versus rituximab alone

RSNA: Genicular Artery Embolization Effective, Safe for Knee Osteoarthritis

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Improvement seen in KOOS quality of life and visual analog scale scores at six months among patients with refractory knee OA

Fast-Acting Sub-Perception Therapy Spinal Cord Stimulation Reduces Back Pain

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In addition, improvement in disability seen, with high patient satisfaction

RSNA: Obesity, VAT Linked to Measures of Amyloid Burden in Midlife

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Visceral adipose tissue had significant direct effect on amyloid burden, which was not explained by HOMA-IR

RSNA: Silicosis Often Missed in Engineered Stone Countertop Workers

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Recognition of silicosis at initial encounter was 19 percent by primary clinicians and 33 percent by radiologists