Archives
ASCO: Ivonescimab Improves Progression-Free Survival in EGFR+ Lung Cancer
PFS benefit seen in most subgroups, including those whose disease progressed while receiving third-generation EGFR-TKIs
ASCO: Osimertinib Improves Progression-Free Survival in EGFR-Mutated Lung Cancer
Significantly longer progression-free survival, but not overall survival, seen for osimertinib in unresectable EGFR-mutation NSCLC
ASCO: Neoadjuvant Ipilimumab + Nivolumab Ups Survival in Resectable Melanoma
Neoadjuvant treatment followed by surgery results in longer event-free survival for resectable, macroscopic stage III melanoma
ASCO: Asciminib Has Superior Efficacy to TKIs for Newly Diagnosed Leukemia
More patients receiving asciminib than investigator-selected tyrosine kinase inhibitor had major molecular response at 48 weeks
ENDO: Crinecerfont Aids Patients With Congenital Adrenal Hyperplasia
Crinecerfont results in greater decrease from baseline in mean daily glucocorticoid dose among patients with CAH
ASCO: Stepped-Care Model Noninferior to Early Palliative Care for Advanced Cancer
Fewer palliative care visits seen with stepped-care model, but noninferiority seen in the Functional Assessment of Cancer Therapy-Lung score
BMI Cutoff of 30 for Obesity May Be Too High for Middle-Aged, Older Adults
Authors found that BMI of ≥27 shows excellent diagnostic performance
Semaglutide Cuts Risk for Kidney Outcomes, Death in CKD With T2DM
Reduction seen in risk for clinically important kidney outcomes and death from cardiovascular causes
Pulmonologist Intervention Beneficial for Undiagnosed Asthma, COPD
Those receiving pulmonologist-directed treatment have less subsequent health care utilization for respiratory illness
Researchers Compare Race-Based, Race-Neutral Lung Function Equations
Similarly accurate prediction seen for respiratory outcomes, but occupational eligibility and disability compensation differed