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ASCO: Ivonescimab Improves Progression-Free Survival in EGFR+ Lung Cancer

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PFS benefit seen in most subgroups, including those whose disease progressed while receiving third-generation EGFR-TKIs

ASCO: Osimertinib Improves Progression-Free Survival in EGFR-Mutated Lung Cancer

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Significantly longer progression-free survival, but not overall survival, seen for osimertinib in unresectable EGFR-mutation NSCLC

ASCO: Neoadjuvant Ipilimumab + Nivolumab Ups Survival in Resectable Melanoma

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Neoadjuvant treatment followed by surgery results in longer event-free survival for resectable, macroscopic stage III melanoma

ASCO: Asciminib Has Superior Efficacy to TKIs for Newly Diagnosed Leukemia

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More patients receiving asciminib than investigator-selected tyrosine kinase inhibitor had major molecular response at 48 weeks

ENDO: Crinecerfont Aids Patients With Congenital Adrenal Hyperplasia

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Crinecerfont results in greater decrease from baseline in mean daily glucocorticoid dose among patients with CAH

ASCO: Stepped-Care Model Noninferior to Early Palliative Care for Advanced Cancer

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Fewer palliative care visits seen with stepped-care model, but noninferiority seen in the Functional Assessment of Cancer Therapy-Lung score

BMI Cutoff of 30 for Obesity May Be Too High for Middle-Aged, Older Adults

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Authors found that BMI of ≥27 shows excellent diagnostic performance

Semaglutide Cuts Risk for Kidney Outcomes, Death in CKD With T2DM

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Reduction seen in risk for clinically important kidney outcomes and death from cardiovascular causes

Pulmonologist Intervention Beneficial for Undiagnosed Asthma, COPD

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Those receiving pulmonologist-directed treatment have less subsequent health care utilization for respiratory illness

Researchers Compare Race-Based, Race-Neutral Lung Function Equations

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Similarly accurate prediction seen for respiratory outcomes, but occupational eligibility and disability compensation differed