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Clinical benefit of reduced low-density lipoprotein cholesterol levels may depend on the corresponding reduction in apolipoprotein B-containing lipoprotein particles

ApoB Levels More Closely Tied to Reduced CVD Events Than LDL

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Change in apoB levels may be better predictor of clinical response than LDL-C, HDL-C levels
Coffee is associated with a lower risk of all-cause mortality

Coffee Consumption Linked to Improved Longevity

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Four cups a day could reduce risk by 64 percent, researchers say
For patients with suspected acute myocardial infarction without hypoxemia

Oxygen Doesn’t Reduce Mortality in Suspected Acute MI

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Routine use of supplemental oxygen does not reduce one-year all-cause mortality versus ambient air
Rivaroxaban plus aspirin is superior to aspirin alone for patients with stable atherosclerotic vascular disease

Rivaroxaban Plus Aspirin Superior for Stable Atherosclerotic Disease

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Primary outcome for fewer patients receiving rivaroxaban plus aspirin, but more major bleeding
Many patients at risk for atrial fibrillation probably do have the condition but have not been diagnosed

Incidence of Undiagnosed A-Fib May Be Substantial

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In new study using insertable cardiac monitors, rate of AF detection was 40 percent at 30 months
Bivalirudin is not associated with a lower rate of the composite of any cause death

No Reduction in Composite End Point for Bivalirudin in PCI

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Patients receiving bivalirudin vs heparin saw no reduction in composite of death, MI, major bleeding
For patients with atrial fibrillation who undergo percutaneous coronary intervention

Dual Therapy Noninferior to Triple Therapy for A-Fib With PCI

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And lower risk of bleeding with dabigatran and P2Y12 inhibitor dual therapy versus triple therapy
Canakinumab at a dose of 150 mg every three months is associated with reduced rate of cardiovascular events among patients with previous myocardial infarction

Canakinumab 150 mg Tied to Reduced Rate of Cardiac Events

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150-mg dose met prespecified threshold for significance for primary and secondary end points

APA: Population of Older Adults With HIV Increasing

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Guidance to address ageism in HIV care includes targeting older adults with prevention, education

APA: Reasons for Underuse of Buprenorphine by PCPs ID’d

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Doctors not willing to increase prescribing due to lack of belief in agonist tx, lack of time for more patients