Home Infectious Disease June 2019 Briefing – Infectious Disease

June 2019 Briefing – Infectious Disease

Here are what the editors at HealthDay consider to be the most important developments in Infectious Disease for June 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Review: HPV Vaccination Program Has Considerable Impact

FRIDAY, June 28, 2019 (HealthDay News) — The human papillomavirus (HPV) vaccination program has had a considerable impact, according to a study published online June 26 in The Lancet.

Infections Tied to Subsequent Risk for Acute Ischemic Stroke

FRIDAY, June 28, 2019 (HealthDay News) — Different infection types, especially urinary tract infection (UTI), are associated with subsequent acute ischemic stroke, according to a study published online June 27 in Stroke.

Increase Seen in Cryptosporidiosis Outbreaks From 2007 to 2019

FRIDAY, June 28, 2019 (HealthDay News) — From 2009 to 2017, there was an increase in the annual number of reported cryptosporidiosis outbreaks in the United States, according to a study published online June 27 in Morbidity and Mortality Weekly Report.

Less Than 40 Percent of All U.S. Adults Have Ever Had HIV Testing

THURSDAY, June 27, 2019 (HealthDay News) — The percentage of U.S. adults undergoing HIV testing nationwide is less than 40 percent, according to a study published online June 27 in Morbidity and Mortality Weekly Report.

ACIP: Men as Old as 26 Should Get HPV Vaccine

THURSDAY, June 27, 2019 (HealthDay News) — The recommended maximum age for male HPV vaccination should be raised from 21 to 26 years, a U.S. government advisory group said.

AP News Article – HPV
AP News Article – Prevnar 13

MSSP ACOs May Not Improve Spending, Quality of Care

WEDNESDAY, June 26, 2019 (HealthDay News) — After adjustment for the nonrandom exit of clinicians, the Medicare Shared Savings Program (MSSP) is not associated with improvements in spending or quality, according to a study published online June 18 in the Annals of Internal Medicine.

Americans Concerned About Clinician Burnout

WEDNESDAY, June 26, 2019 (HealthDay News) — Nearly three-quarters of Americans are concerned about burnout among their clinicians, according to a survey released June 17 by the American Society of Health-System Pharmacists (ASHP).

Prevention Bundle May Cut Cardiac Device Infections

WEDNESDAY, June 26, 2019 (HealthDay News) — Standardized protocols and bundles can improve infection prevention in the electrophysiology laboratory, according to a study published online June 4 in Infection Control & Hospital Epidemiology.

Death From Specific Causes Up for Veterans With PTSD

MONDAY, June 24, 2019 (HealthDay News) — Among veterans with posttraumatic stress disorder (PTSD), all-cause mortality is elevated, especially death from suicide, accidental injury, and viral hepatitis, according to a study published online June 24 in the American Journal of Preventive Medicine.

Many Trust Doctors, Nurses Over Other Sources of Health Advice

MONDAY, June 24, 2019 (HealthDay News) — Globally, about three-quarters of people trust doctors or nurses more than other sources when it comes to health advice, according to a report published online June 19 by the Wellcome Global Monitor.

Rotavirus Vaccine Led to Reduced Disease Prevalence, Season Duration

MONDAY, June 24, 2019 (HealthDay News) — Implementation of rotavirus vaccination has reduced disease prevalence and season duration in the United States, according to research published in the June 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Oral Steroids Increase Infection Risk in Inflammatory Disease

MONDAY, June 24, 2019 (HealthDay News) — The incidence of infection increases with glucocorticoid dose for patients with polymyalgia rheumatica or giant cell arteritis, according to a study published online June 24 in CMAJ, the journal of the Canadian Medical Association.

New England Journal of Medicine Picks New Editor-in-Chief

THURSDAY, June 20, 2019 (HealthDay News) — The new editor-in-chief of the prestigious New England Journal of Medicine is Eric J. Rubin, M.D., Ph.D., who was selected after a worldwide search and plans to start in September, according to the Massachusetts Medical Society, which publishes the journal.

2018 to 2019 Influenza Season in U.S. Was Longest in 10 Years

THURSDAY, June 20, 2019 (HealthDay News) — In the United States, the 2018 to 2019 influenza season was of moderate severity and lasted 21 weeks, according to research published in the June 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Health Care Workers With ARIs Often Work While Symptomatic

THURSDAY, June 20, 2019 (HealthDay News) — Almost all health care workers (HCWs) with acute respiratory illness (ARI) report working at least one day while symptomatic, according to a study published online June 18 in Infection Control & Hospital Epidemiology.

Surgeons’ Unprofessional Behavior Tied to Higher Complication Risk

WEDNESDAY, June 19, 2019 (HealthDay News) — Patients whose surgeons have higher numbers of coworker reports about unprofessional behavior may be at increased risk for postsurgical complications, according to a study published online June 19 in JAMA Surgery.

Drug Makers Challenge New Rule Requiring Drug Prices in TV Ads

MONDAY, June 17, 2019 (HealthDay News) — Three large drug makers have launched a legal challenge against the Trump administration’s rule requiring the prices of drugs to be included in television ads.

The New York Times Article

WHO: Congo Ebola Outbreak Still Not Global Emergency

MONDAY, June 17, 2019 (HealthDay News) — Even though the Ebola outbreak in Congo recently caused deaths in neighboring Uganda, it is still not a global emergency, the World Health Organization says.

AP News Article

CDC: U.S. Measles Cases Reach 1,044

MONDAY, June 17, 2019 (HealthDay News) — The number of measles cases in the United States so far this year has reached 1,044 in 28 states, the U.S. Centers for Disease Control and Prevention says.

U.S. Travelers Should Be Aware of Measles Risk in Europe

MONDAY, June 17, 2019 (HealthDay News) — U.S. travelers need to be aware of measles in Europe and should ensure children are adequately vaccinated, according to a study published online June 17 in Pediatrics.

FDA Warns of Infections From Fecal Transplants After One Death

FRIDAY, June 14, 2019 (HealthDay News) — On Thursday, federal health officials announced that a patient has died after fecal microbiota transplantation, highlighting the potential for severe infections linked to the procedure.

New York State Halts Religious Vaccine Exemption

FRIDAY, June 14, 2019 (HealthDay News) — Reacting to an ongoing measles outbreak, New York state has eliminated the religious exemption for not vaccinating children.

AP News Article

Rotavirus Vaccination Tied to Lower Risk for T1DM in Children

FRIDAY, June 14, 2019 (HealthDay News) — Completion of full rotavirus vaccination appears to be associated with a reduction in the risk of type 1 diabetes in children, according to a study published online June 13 in Scientific Reports.

CDC Opens Emergency Operations Center for Congo Ebola Outbreak

THURSDAY, June 13, 2019 (HealthDay News) — The United States is stepping up its response to a historic outbreak of Ebola in two African nations. The U.S. Centers for Disease Control and Prevention activated its Emergency Operations Center Thursday to assist in the government’s response to the second-largest outbreak of Ebola on record.

HIV Risk Does Not Differ With Three Contraceptive Methods

THURSDAY, June 13, 2019 (HealthDay News) — For African women seeking effective contraception, there is no significant difference in HIV incidence with use of intramuscular depot medroxyprogesterone acetate (DMPA-IM), a copper intrauterine device (IUD), and a levonorgestrel (LNG) implant, according to a study published online June 13 in The Lancet.

HPV16 Antibodies Can Develop Long Before Throat Cancer Diagnosis

THURSDAY, June 13, 2019 (HealthDay News) — Seroconversion to human papillomavirus type 16 (HPV16)-E6 antibody positivity can occur decades before diagnosis of oropharyngeal squamous cell carcinoma (OPSCC), according to a study published online June 12 in the Annals of Oncology.

Most Providers Unaware of Online Feedback About Themselves

WEDNESDAY, June 12, 2019 (HealthDay News) — Many health care providers in the United Kingdom have little direct experience with online feedback, rarely encourage it, and often view it as having little value for improving the quality of health services, according to a study published online June 2 in the Journal of Health Services Research & Policy.

CDC: Wildlife Rabies, Especially in Bats, Poses Risk in U.S.

WEDNESDAY, June 12, 2019 (HealthDay News) — Wildlife rabies, especially in bats, poses a risk to humans in the United States, and postexposure prophylaxis (PEP) is important for preventing death, according to research published in the June 12 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Next-Gen Sequencing of CSF Improves Diagnosis of CNS Infections

WEDNESDAY, June 12, 2019 (HealthDay News) — Metagenomic next-generation sequencing (NGS) of cerebrospinal fluid (CSF) obtained from patients with meningitis or encephalitis can improve diagnosis of neurologic infections, according to a study published in the June 13 issue of the New England Journal of Medicine.

Microbes Tied to Pedicle Screw Loosening, Spinal Implant Failure

WEDNESDAY, June 12, 2019 (HealthDay News) — Low-virulent microorganisms frequently detected on pedicle screws may be an important cause of spinal implant loosening and failure in patients without signs of infection, according to a study recently published in the Journal of Neurosurgery: Spine.

Nurse Understaffing Ups Inpatient Infection Risk

TUESDAY, June 11, 2019 (HealthDay News) — Nurse understaffing is associated with an increased risk for health care-associated infections (HAIs) among hospitalized patients, according to a study published in the May issue of the Journal of Nursing Administration.

Pertussis Risk Up for Undervaccinated, Unvaccinated Children

TUESDAY, June 11, 2019 (HealthDay News) — Undervaccinated and unvaccinated children are at increased risk for pertussis, but most cases occur in vaccinated children further away from their last vaccine dose, according to a study published online June 10 in Pediatrics.

Diagnostic Testing, Antibiotics Overused in Pediatric CAP

TUESDAY, June 11, 2019 (HealthDay News) — Children with community-acquired pneumonia (CAP) often receive diagnostic testing and antibiotic therapy despite publication of guidelines against their routine use in 2011, according to a study published online May 20 in the Journal of the Pediatric Infectious Diseases Society.

Access to Health Care Has Little Impact on Longevity

MONDAY, June 10, 2019 (HealthDay News) — Health care has modest effects on extending life expectancy in the United States, while behavioral and social determinants may have larger effects, according to a review published in the May/June issue of the Annals of Family Medicine.

Cough Sound Analyzer Helps Differentiate Peds Respiratory Disorders

MONDAY, June 10, 2019 (HealthDay News) — An automated cough sound analyzer can serve as a diagnostic aid in the assessment of pediatric respiratory disorders, according to a study published online June 6 in Respiratory Research.

2003 to 2014 Saw Incidence of Herpes Zoster Drop in Children

MONDAY, June 10, 2019 (HealthDay News) — From 2003 to 2014, there was a decrease in herpes zoster (HZ) incidence among children, with lower incidence rates for varicella-vaccinated versus unvaccinated children, according to a study published online June 10 in Pediatrics.

Mouth Rinse for HPV DNA May Be Biomarker in Head, Neck Cancer

MONDAY, June 10, 2019 (HealthDay News) — Human papillomavirus (HPV) DNA detected from a mouth rinse may be an effective marker for prognosis during treatment of HPV-positive head and neck cancer, according to a study recently published in JAMA Oncology.

Antibiotic Prophylaxis Before Dental Work Often Unnecessary

FRIDAY, June 7, 2019 (HealthDay News) — Antibiotic prophylaxis before dental procedures is unnecessary more than 80 percent of the time, according to a study published online May 31 in JAMA Network Open.

WHO: Estimated Incidence of Curable STIs 376.4 Million in 2016

THURSDAY, June 6, 2019 (HealthDay News) — The estimated incidence of urogenital infections with chlamydia, gonorrhea, trichomoniasis, and syphilis was 376.4 million in 15- to 49-year-old men and women in 2016, according to research published online June 6 in the Bulletin of the World Health Organization.

Rapid Cycling Work Roster Improves Resident Sleep Practices

THURSDAY, June 6, 2019 (HealthDay News) — A rapidly cycling work roster (RCWR) is effective in reducing weekly work hours and the occurrence of >16 consecutive-hour shifts as well as improving sleep duration of resident physicians, according to a study published online May 20 in SLEEP.

Survey Indicates Physician Misconduct Is Underreported

THURSDAY, June 6, 2019 (HealthDay News) — Physician misconduct is being underreported and most Americans do not know where to file a complaint, according to a report published by the Federation of State Medical Boards (FSMB).

Parkinson Disease Incidence Lower in Hep C Patients Who Receive Antivirals

THURSDAY, June 6, 2019 (HealthDay News) — The incidence of Parkinson disease (PD) is lower for patients with chronic hepatitis C virus (HCV) infection who receive interferon-based antiviral therapy, according to a study published online June 5 in JAMA Neurology.

Workplace Exposures Contribute to Burden of Respiratory Disease

WEDNESDAY, June 5, 2019 (HealthDay News) — Workplace exposures contribute to the burden of respiratory conditions, according to a statement issued by the American Thoracic Society and European Respiratory Society and published in the June 1 issue of the American Journal of Respiratory and Critical Care Medicine.

Staphylococcus aureus Linked to Food Sensitization in Eczema

TUESDAY, June 4, 2019 (HealthDay News) — For children with eczema, Staphylococcus aureus (S. aureus) colonization is associated with food sensitization and allergy independent of eczema severity, according to a study published online May 31 in the Journal of Allergy and Clinical Immunology.

Zerbaxa Approved for Hospital-Acquired Bacterial Pneumonia

TUESDAY, June 4, 2019 (HealthDay News) — Zerbaxa (ceftolozane and tazobactam) has been approved for a new indication to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP) in patients aged 18 years and older, the U.S. Food and Drug Administration announced yesterday.

Immunizations Up in California After Repeal of Nonmedical Exemptions

TUESDAY, June 4, 2019 (HealthDay News) — The repeal of nonmedical vaccine exemptions in California was only partially effective in improving vaccination coverage, according to a working paper issued by the National Bureau of Economic Research.

Peripherally Inserted Central Catheters Often Used in CKD

MONDAY, June 3, 2019 (HealthDay News) — Peripherally inserted central catheters (PICCs) are frequently used in hospitalized patients with stage 3b or greater chronic kidney disease (estimated glomerular filtration rate [eGFR], <45 mL/min/1.73 m²), according to a study published online June 4 in the Annals of Internal Medicine.

ACP Issues Position on Response to Physician Impairment

MONDAY, June 3, 2019 (HealthDay News) — Providing assistance for physician impairment and rehabilitation is addressed in a position statement issued by the American College of Physicians and published online June 4 in the Annals of Internal Medicine.

Guidelines Issued for Addressing Heart Disease Risk in HIV

MONDAY, June 3, 2019 (HealthDay News) — People living with HIV (PLWH) have an increased risk for cardiovascular disease (CVD), a risk that needs appropriate management and treatment, according to a scientific statement issued by the American Heart Association and published online June 3 in Circulation.

Current Strategies for Measles Vaccination Insufficient

MONDAY, June 3, 2019 (HealthDay News) — Compulsory vaccination at school entry in addition to current immunization programs will be necessary in several high-income countries to prevent future measles resurgence, according to a study published online May 17 in BMC Medicine.

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