July 2020 Briefing – Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for July 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 27 to 31, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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U.S. Puts Up Another $2.1 Billion for Potential COVID-19 Vaccine

FRIDAY, July 31, 2020 (HealthDay News) — The United States is buying up another potential COVID-19 vaccine, the Associated Press reported Friday.

AP News Article

Telemedicine Use Explodes During COVID-19 Pandemic

FRIDAY, July 31, 2020 (HealthDay News) — The emergence of telemedicine has accelerated during the coronavirus pandemic. HD Live! sat down with Rujuta Saksena, M.D., an oncologist at Overlook Medical Center in Summit, New Jersey, and Ateev Mehrotra, M.D., associate professor of health care policy at Harvard Medical School in Boston, to discuss the future of telemedicine and its impact on health care.

Plenty of COVID-19 Vaccine Coming, Fauci Says

FRIDAY, July 31, 2020 (HealthDay News) — When a COVID-19 vaccine is approved, there should be plenty of it available, Anthony Fauci, M.D., infectious diseases chief at the U.S. National Institutes of Health, told a House panel Friday, the Associated Press reported.

AP News Article
Johns Hopkins University

Inflammation Tied to Thyroid Dysfunction With Psoriasis

FRIDAY, July 31, 2020 (HealthDay News) — Thyroid dysfunction in patients with psoriasis may be associated with inflammation caused by psoriasis, according to a study published online June 22 in the Journal of Dermatology.

Global Epidemiology of COVID-19 Reported for Prepandemic Era

FRIDAY, July 31, 2020 (HealthDay News) — Many of the first COVID-19 cases reported from affected countries outside of mainland China involved recent travel to affected countries, according to a study published online July 29 in The Lancet Infectious Diseases.

Bacterial, Fungal Coinfection Uncommon in COVID-19 Patients

FRIDAY, July 31, 2020 (HealthDay News) — Bacterial and fungal infections are uncommon in hospitalized COVID-19 patients, but coinfection is associated with high mortality and antibiotic use is widespread, according to a study published in the July issue of Infection Control & Hospital Epidemiology.

Survivors of Adolescent, Young Adult ALL May Suffer Late Effects

FRIDAY, July 31, 2020 (HealthDay News) — Survivors of adolescent and young adult (AYA) acute lymphoblastic leukemia (ALL) may experience late effects, with a high incidence of subsequent endocrine disease and cardiac disease, according to a study published in the August issue of JNCI Cancer Spectrum.

Second BMD Measurement Not Beneficial for Identifying Hip Fracture

FRIDAY, July 31, 2020 (HealthDay News) — A second bone mineral density (BMD) assessment about three years after initial measurement does not improve discrimination beyond baseline BMD value alone for women who do and do not experience subsequent hip fracture or major osteoporotic fracture, according to a study published online July 27 in JAMA Internal Medicine.

Sex Differences in Income Vary With Proportion of Male Doctors

FRIDAY, July 31, 2020 (HealthDay News) — For surgical and nonsurgical specialists, sex differences in income vary with the proportion of male physicians in a practice, according to a study published online July 30 in The BMJ.

Dual Sensory Impairment Ups Dementia Risk

FRIDAY, July 31, 2020 (HealthDay News) — Older adults with both hearing and visual impairments — dual sensory impairment (DSI) — are at a significantly increased risk for dementia, according to a study published online July 7 in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring.

Early Age at Menarche Tied to Frequent Menopausal Symptoms

FRIDAY, July 31, 2020 (HealthDay News) — Early age at menarche is a risk factor for menopausal symptoms, according to a study published online July 21 in BJOG: An International Journal of Obstetrics & Gynaecology.

FDA Warns Companies Illegally Selling Hangover Cures

THURSDAY, July 30, 2020 (HealthDay News) — The U.S. Food and Drug Administration has sent warning letters to seven companies for illegally selling products they claim will cure, treat, mitigate, or prevent hangovers.

Excessive Drinking Responsible for 255 Deaths Per Day in U.S.

THURSDAY, July 30, 2020 (HealthDay News) — Excessive drinking was responsible for an average of 255 deaths per day in the United States during 2011 to 2015, according to research published in the July 31 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

School Closures Linked to Decreased COVID-19 Incidence, Death

THURSDAY, July 30, 2020 (HealthDay News) — School closures in the United States were temporally associated with decreased COVID-19 incidence and mortality, according to a study published online July 29 in the Journal of the American Medical Association.

Young Children Have Higher Amounts of SARS-CoV-2 RNA

THURSDAY, July 30, 2020 (HealthDay News) — Young children with mild-to-moderate COVID-19 have higher amounts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA in their nasopharynx than older children and adults, according to a research letter published online July 30 in JAMA Pediatrics.

Study IDs Which Women Benefit From DBT Versus Digital Mammography

THURSDAY, July 30, 2020 (HealthDay News) — Improvements in recall rates and cancer detection rates with digital breast tomosynthesis (DBT) versus digital mammography (DM) are greatest on baseline examinations, according to a study published online July 28 in JAMA Network Open.

ACS Issues Updated Guideline for Cervical Cancer Screening

THURSDAY, July 30, 2020 (HealthDay News) — In a guideline update from the American Cancer Society, published online July 30 in CA: A Cancer Journal for Clinicians, recommendations are presented for cervical cancer screening of individuals at average risk.

Cinnamon Supplementation May Improve Blood Glucose Control

THURSDAY, July 30, 2020 (HealthDay News) — In individuals with prediabetes, 12 weeks of cinnamon supplementation improved fasting plasma glucose (FPG) and glucose tolerance, according to a study published online July 21 in the Journal of the Endocrine Society.

Chocolate Tied to Lower Coronary Artery Disease Risk

THURSDAY, July 30, 2020 (HealthDay News) — Eating chocolate at least once a week is associated with a lower risk for coronary artery disease (CAD), according to a review published online July 22 in the European Journal of Preventive Cardiology.

Delayed Treatment of Upper Respiratory Tract Infections Tied to Hospitalization Risk

THURSDAY, July 30, 2020 (HealthDay News) — Delayed treatment of upper respiratory tract infections (URTI) with antibiotics is associated with an increased risk for hospital admissions, according to a study published online June 29 in Clinical Infectious Diseases.

Study Looks at Phthalates, Sleep Quality in Women at Midlife

WEDNESDAY, July 29, 2020 (HealthDay News) — For midlife women, phthalate exposure seems to be associated with sleep disruption, with the associations observed in nonsmokers or former smokers, according to a study published online July 29 in Menopause.

Decrease Seen in Products Purchased Containing Caloric Sweeteners

WEDNESDAY, July 29, 2020 (HealthDay News) — From 2002 to 2018, there was a decrease in the volume of products purchased containing caloric sweeteners (CS) and an increase in purchases of products containing both CS and nonnutritive sweeteners (NNS), according to a study published online July 29 in the Journal of the Academy of Nutrition and Dietetics.

Poor Dental Health May Increase Risk for Incident Dementia, MCI

WEDNESDAY, July 29, 2020 (HealthDay News) — Individuals with severe periodontal disease or edentulism have an increased risk for incident dementia, according to a study published online July 29 in Neurology.

More Diabetic Foot Amputations Seen During COVID-19 Lockdown

WEDNESDAY, July 29, 2020 (HealthDay News) — Patients with diabetes admitted to a tertiary care center for diabetic foot ulceration (DFU) during the COVID-19 lockdown in Italy had a more than threefold risk for amputation versus patients seen in 2019, according to a study published online July 23 in Diabetes Care.

Latino Communities at Higher Risk for COVID-19

WEDNESDAY, July 29, 2020 (HealthDay News) — Factors linked to structural racism and social determinants of health are associated with an increased risk for COVID-19 in Latino communities, according to a study published online July 23 in the Annals of Epidemiology.

Cancer-Related Encounters Down Since Start of COVID-19

WEDNESDAY, July 29, 2020 (HealthDay News) — There has been a decrease in cancer-related encounters and in cancer screening since the start of the COVID-19 pandemic, according to a study published online July 27 in JCO: Clinical Cancer Informatics.

Obesity in Young Adulthood Tied to Later Venous Thromboembolism

WEDNESDAY, July 29, 2020 (HealthDay News) — Men who are obese or severely obese in young adulthood have an increased risk for venous thromboembolism (VTE) later in life, according to a study published in the June issue of the Journal of Internal Medicine.

Low Health Literacy Tied to Worse Heart Failure Outcomes

WEDNESDAY, July 29, 2020 (HealthDay News) — Poor health literacy is associated with worse heart failure outcomes, according to a review published in the June issue of JACC: Heart Failure.

Depression, Anxiety May Be Signs That COVID-19 Is Attacking Brain

WEDNESDAY, July 29, 2020 (HealthDay News) — Depression and anxiety exhibited in COVID-19 patients may be a sign that the virus impacts the central nervous system, as these symptoms are closely associated with a loss of smell and taste rather than more severe manifestations of the virus, according to a study published online July 2 in The Laryngoscope.

Smoking Ups Risk for Unruptured Intracranial Aneurysm in Women

WEDNESDAY, July 29, 2020 (HealthDay News) — Women aged 30 to 60 years with a positive smoking history and underlying hypertension have an increased risk for having an unruptured intracranial aneurysm (UIA), according to a study published online July 28 in the Journal of Neurology, Neurosurgery & Psychiatry.

Premature Cardiac Deaths Across U.S. Dropped From 1999 to 2017

WEDNESDAY, July 29, 2020 (HealthDay News) — The rate of premature cardiac deaths (PCDs) decreased across U.S. counties from 1999 to 2017, although widening geographic disparities have been observed, according to a study published online July 29 in the Journal of the American Heart Association.

Nearly Half of Hispanics, Blacks Scared to Go to Hospital During COVID-19

WEDNESDAY, July 29, 2020 (HealthDay News) — Hispanics and blacks are most likely to stay home if experiencing medical emergencies, like a heart attack or stroke, to avoid the risk of contracting COVID-19 at the hospital, according to a poll released by the American Heart Association (AHA).

SGLT-2 Inhibitors May Raise Risk for Diabetic Ketoacidosis

WEDNESDAY, July 29, 2020 (HealthDay News) — In patients with type 2 diabetes, sodium-glucose cotransporter-2 (SGLT-2) inhibitors are associated with an increased risk for diabetic ketoacidosis (DKA), according to a study published online July 28 in the Annals of Internal Medicine.

Incidence of Hip Fracture Decreased From 1970 to 2010

TUESDAY, July 28, 2020 (HealthDay News) — The incidence of hip fracture decreased from 1970 to 2010, with reductions in smoking and heavy drinking coincident with this decrease, according to a study published online July 27 in JAMA Internal Medicine.

Myocardial Injury Seen in Many Early in Recovery From COVID-19

TUESDAY, July 28, 2020 (HealthDay News) — Many patients recently recovered from COVID-19 infection have cardiac involvement, according to a study published online July 27 in JAMA Cardiology.

HIV+ Donor to HIV+ Recipient Feasible for Kidney Transplant

TUESDAY, July 28, 2020 (HealthDay News) — HIV-positive donor to HIV-positive recipient (HIV D+/R+) kidney transplantation (KT) is feasible, according to a study published online July 23 in the American Journal of Transplantation.

Increase Found in Suicide-Related Exposure Rates to OTC Analgesics

TUESDAY, July 28, 2020 (HealthDay News) — There has been a recent increase in suicide-related exposure rates to over-the-counter (OTC) analgesics, according to a study published online July 26 in Pharmacoepidemiology & Drug Safety.

FDA Warns Again About Dangers of Methanol-Based Hand Sanitizers

TUESDAY, July 28, 2020 (HealthDay News) — The U.S. Food and Drug Administration is warning consumers not to use alcohol-based hand sanitizers containing methanol, or wood alcohol, which is used in fuel and antifreeze and is toxic if absorbed through the skin or life-threatening if ingested.

Vertebral Fractures Up With Long-Term Delay of Denosumab

TUESDAY, July 28, 2020 (HealthDay News) — Compared with on-time dosing, delay of denosumab by more than 16 weeks is associated with an increased risk for vertebral fractures, according to a study published online July 28 in the Annals of Internal Medicine.

Postmarketing Surveillance Helps Identify Vaccine Safety Issues

TUESDAY, July 28, 2020 (HealthDay News) — A review of all safety-related labeling changes for FDA-approved vaccines during a 20-year period shows vaccines are largely safe, and many of the safety issues are identified through postmarketing surveillance, according to a study published online July 28 in the Annals of Internal Medicine.

NSAID Use Linked to Cardiovascular, Bleeding Events Post-MI

MONDAY, July 27, 2020 (HealthDay News) — For patients with myocardial infarction (MI), nonsteroidal anti-inflammatory drug (NSAID) treatment is associated with a significantly increased risk for cardiovascular and bleeding events, according to a study published in the Aug. 4 issue of the Journal of the American College of Cardiology.

COVID-19 Vaccine Candidate Now in Final Phase Testing

MONDAY, July 27, 2020 (HealthDay News) — A vaccine developed by the U.S. National Institutes of Health and Moderna has entered the final phase of testing, the Associated Press reported Monday.

AP News Article

CDC to Address Inequalities in COVID-19 Reporting

MONDAY, July 27, 2020 (HealthDay News) — The U.S. Centers for Disease Control and Prevention plans to take steps to improve how it collects COVID-19 data for blacks, Hispanics, and Native Americans, the Associated Press reports.

AP News Article

COVID-19 Can Result in Prolonged Illness Even in Milder Cases

MONDAY, July 27, 2020 (HealthDay News) — Even among persons with milder outpatient illness, COVID-19 can result in prolonged illness, according to research published in the July 24 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Large Proportion of COVID-19 Studies Have Low-Level Evidence

MONDAY, July 27, 2020 (HealthDay News) — A large proportion of studies on COVID-19 have a low level of evidence, according to a research letter published online July 27 in JAMA Internal Medicine.

Impact on Glucocorticoids in COVID-19 Varies With CRP Levels

MONDAY, July 27, 2020 (HealthDay News) — The impact of glucocorticoid treatment on patients with COVID-19 varies according to C-reactive protein (CRP) levels, according to a study published online July 22 in the Journal of Hospital Medicine.

Thorough Risk Assessment Essential Prior to Noncardiac Surgery

MONDAY, July 27, 2020 (HealthDay News) — Comprehensive preoperative assessment of cardiovascular risk with history and physical examination is essential prior to noncardiac surgery, according to a review published in the July 21 issue of the Journal of the American Medical Association.

Risk Factors Provide Targets for Preventing Alzheimer Disease

MONDAY, July 27, 2020 (HealthDay News) — Ten risk factors should be targeted to prevent Alzheimer disease, according to a review published online July 20 in the Journal of Neurology, Neurosurgery & Psychiatry.

Obesity Diagnoses Up Among Hospitalized Patients in the U.S.

MONDAY, July 27, 2020 (HealthDay News) — There was an increase in obesity diagnoses in hospitalized patients and bariatric surgeries among those diagnosed with obesity from 2011 to 2014, according to a study published online July 5 in Clinical Obesity.

ASTRO Issues First Guideline on Radiation Therapy for Cervical Cancer

FRIDAY, July 24, 2020 (HealthDay News) — There is strong evidence supporting the use of radiation therapy (RT) for nonmetastatic cervical cancer, according to a clinical practice guideline from the American Society for Radiation Oncology (ASTRO) published in the July/August issue of Practical Radiation Oncology.

FDA: Doctors Should Discuss Opioid OD Antidote With Patients

FRIDAY, July 24, 2020 (HealthDay News) — Doctors should tell patients and caregivers about the overdose antidote naloxone when they prescribe opioid painkillers such as Percocet and OxyContin and medicines to treat opioid addiction, including buprenorphine, methadone, and naltrexone, the U.S. Food and Drug Administration said Thursday.

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 20 to 24, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Midnasal Swab Done by Patient at Home Detects SARS-CoV-2

FRIDAY, July 24, 2020 (HealthDay News) — For detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in symptomatic patients, unsupervised home midnasal swab collection is comparable to clinician-collected nasopharyngeal swab collection, according to a research letter published online July 22 in JAMA Network Open.

Isolation, Quarantine Impossible in >20 Percent of U.S. Homes

FRIDAY, July 24, 2020 (HealthDay News) — More than 20 percent of U.S. homes lack sufficient space or plumbing facilities to comply with recommendations to isolate or quarantine to prevent COVID-19 transmission, according to a research letter published online July 21 in the Annals of Internal Medicine.

CDC Guidance Issued for Testing, Management of HCP Exposed to Hep C

FRIDAY, July 24, 2020 (HealthDay News) — In a U.S. Centers for Disease Control and Prevention guidance report, published in the July 24 issue of Morbidity and Mortality Weekly Report, recommendations are presented for testing and clinical management of health care personnel (HCP) exposed to the hepatitis C virus (HCV).

Mental Health Deteriorated During COVID-19 Lockdown

FRIDAY, July 24, 2020 (HealthDay News) — Mental health deteriorated in the United Kingdom by the end of April 2020 compared with pre-COVID-19 pandemic trends, according to a study published online July 21 in The Lancet Psychiatry.

Chimpanzee Adenovirus-Vectored Vaccine Promising for COVID-19

FRIDAY, July 24, 2020 (HealthDay News) — A chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein has acceptable safety and induces antibody and T-cell immune responses, according to a study published online July 20 in The Lancet.

Long-Term Risk for Severe Kidney Disease High in Those With T2DM

FRIDAY, June 24, 2020 (HealthDay News) — The long-term risk for end-stage kidney disease (ESKD) in type 2 diabetes is high and disproportionately affects those with younger onset of diabetes, according to a study published online June 15 in Diabetes Care.

Worse Multisensory Function May Accelerate Cognitive Aging

FRIDAY, July 24, 2020 (HealthDay News) — Worsening multisensory function is associated with accelerated cognitive aging, according to a study published online July 12 in Alzheimer’s & Dementia.

Financial Health of Hospitals ‘Dire’ Due to COVID-19

THURSDAY, July 23, 2020 (HealthDay News) — COVID-19 continues to cause financial peril for U.S. hospitals, according to a report released by the American Hospital Association (AHA).

New Guidelines Released for Recovering COVID-19 Patients to Leave Isolation

THURSDAY, July 23, 2020 (HealthDay News) — Many recovering COVID-19 patients in the United States will now be able to leave isolation without further testing to show they are virus-free, the U.S. Centers for Disease Control and Prevention said Wednesday.

The New York Times Article

High Prevalence of Americans Have Conditions Linked to Severe COVID-19

THURSDAY, July 23, 2020 (HealthDay News) — The median prevalence of any underlying medical condition that increases the risk for severe COVID-19-associated illness is 47.2 percent among residents in all 50 states and the District of Columbia, according to research published in the July 24 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Three in Four Americans Favor Face Coverings: Survey

THURSDAY, July 23, 2020 (HealthDay News) — Face coverings should be worn by people when they leave home, three-quarters of Americans say in a new poll.

AP News Article

Diets High in Protein, Plant Protein Tied to Lower Mortality

THURSDAY, July 23, 2020 (HealthDay News) — Plant protein intake is associated with a lower risk for all-cause and cardiovascular disease mortality, according to a review published online July 22 in The BMJ.

Ad5-Vectored COVID-19 Vaccine Immunogenic in Healthy Adults

THURSDAY, July 23, 2020 (HealthDay News) — The nonreplicating adenovirus type-5 (Ad5)-vectored COVID-19 vaccine appears safe and induces immune responses at a dose of 5×10¹⁰ viral particles, according to a study published online July 20 in The Lancet.

Most Individuals in U.S. Have Not Been Infected With SARS-CoV-2

THURSDAY, July 23, 2020 (HealthDay News) — During March to early May 2020, most individuals in the United States had not been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), although the estimated number of infections seems to have been much higher than the number of reported cases, according to a study published online July 21 in JAMA Internal Medicine.

Data Reviewed for Levonorgestrel IUD Use in Youth With Disability

THURSDAY, July 23, 2020 (HealthDay News) — Data from a retrospective chart review suggest that levonorgestrel (LNG) intrauterine devices (IUDs) may be a useful option for menstrual management and contraception in adolescents and young adults with physical, intellectual, and developmental disabilities, according to a study published online July 23 in Pediatrics.

Few Dementia Caregivers Receive Firearm Safety Counseling

THURSDAY, July 23, 2020 (HealthDay News) — Few caregivers of adults with Alzheimer disease and related dementias (ADRD) receive professional counseling about firearm safety, according to a study published online July 15 in JAMA Network Open.

Too Much, Too Little Sleep May Up Mortality in Patients With T2DM

THURSDAY, July 23, 2020 (HealthDay News) — In people with type 2 diabetes, sleeping more or less than seven hours/day is associated with an increased risk for all-cause and condition-specific mortality, according to a study published online July 16 in Diabetologia.

Varenicline Strongly Recommended for Smoking Cessation

THURSDAY, July 23, 2020 (HealthDay News) — Varenicline is strongly recommended over the patch for adult smokers hoping to quit, according to an American Thoracic Society practice guideline published online in the July 15 issue of the American Journal of Respiratory and Critical Care Medicine.

Predictors of Amyloid-β Deposits Identified in Oldest Old

WEDNESDAY, July 22, 2020 (HealthDay News) — Predictors of amyloid-β (Aβ) deposition have been identified in the oldest old, according to a study published online July 22 in Neurology.

Routine Hepatitis C Testing at FQHCs Would Be Cost-Effective

WEDNESDAY, July 22, 2020 (HealthDay News) — Routine hepatitis C virus (HCV) testing at federally qualified health centers (FQHCs) would be cost-effective and could improve outcomes for people with HCV infections, according to a study published online June 27 in The American Journal of Medicine.

U.S. Reaches Deal for Nearly 600 Million Doses of COVID-19 Vaccine

WEDNESDAY, July 22, 2020 (HealthDay News) — A nearly $2 billion contract with pharmaceutical company Pfizer and a German biotechnology firm will provide the United States with up to 600 million doses of a COVID-19 vaccine being developed by the companies, the U.S. government says.

The New York Times Article

Salmonella Outbreak in 15 States Being Investigated by CDC

WEDNESDAY, July 22, 2020 (HealthDay News) — A Salmonella outbreak that has sickened 125 people in 15 states is being investigated by the U.S. Centers for Disease Control and Prevention.

Inpatient Imaging Volumes Down During COVID-19 Pandemic

WEDNESDAY, July 22, 2020 (HealthDay News) — During the COVID-19 pandemic, there has been a decrease in inpatient imaging volumes, according to a study published online June 18 in the Journal of the American College of Radiology.

Elective Services in Pulmonary, Sleep Medicine to Resume During COVID-19

WEDNESDAY, July 22, 2020 (HealthDay News) — In a guidance document issued by an American Thoracic Society-led international task force, published online July 14 in the Annals of the American Thoracic Society, recommendations are presented for the resumption of elective in-person clinical services in pulmonary and sleep medicine.

CDC: Former Smokers Have Higher Levels of Fair, Poor Health

WEDNESDAY, July 22, 2020 (HealthDay News) — Smoking cessation is beneficial, but even after cessation, former smokers have worse health measures, according to a study published online July 22 in National Health Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

Epidemiology of Herpes Simplex Virus in Europe Transitioning

WEDNESDAY, July 22, 2020 (HealthDay News) — The epidemiology of herpes simplex virus (HSV)-1 is transitioning away from oral acquisition in childhood with an increasing proportion of HSV-1 detection in genital herpes, according to a study published online July 16 in BMJ Global Health.

Some With Opioid Use Disorder Rejected From Post-Acute Care

WEDNESDAY, July 22, 2020 (HealthDay News) — Individuals hospitalized with opioid use disorder (OUD) frequently experience explicit discrimination when being rejected from post-acute care, according to a study published online July 15 in the Journal of Addiction Medicine.

U.K. Study Looks at Stepping Down Meds in Stable Asthma

TUESDAY, July 21, 2020 (HealthDay News) — Asthma patients are increasingly prescribed higher levels of treatment, and few patients step down medications, according to a study published online July 21 in PLOS Medicine.

Levels of Chronic Kidney Disease Stabilizing in the United States

TUESDAY, July 21, 2020 (HealthDay News) — The prevalence of chronic kidney disease (CKD) in the United States has stabilized in recent years, according to a study published online July 16 in JAMA Network Open.

11.8 Percent of Household Contacts of Index Patients Have COVID-19

TUESDAY, July 21, 2020 (HealthDay News) — Overall, 11.8 percent of household contacts of index COVID-19 patients in South Korea have COVID-19 compared with 1.9 percent of nonhousehold contacts, according to a study published online July 16 in Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention.

Rise in Avoidable Cancer Deaths Expected Due to COVID-19

TUESDAY, July 21, 2020 (HealthDay News) — An increase in the number of avoidable cancer deaths is expected in England as a result of diagnostic delays due to the COVID-19 pandemic, according to a study published online July 20 in The Lancet Oncology.

More Online Advance Directives Completed During COVID-19

TUESDAY, July 21, 2020 (HealthDay News) — There has been an increase in completion of advance directives (ADs) during the COVID-19 pandemic, according to a research letter published online July 20 in JAMA Network Open.

Even Mild Obesity Tied to Significantly Worse COVID-19 Outcomes

TUESDAY, July 21, 2020 (HealthDay News) — Obesity is a strong, independent risk factor for poor outcomes among COVID-19 patients, according to a study published July 1 in the European Journal of Endocrinology.

Periodontal Disease, Tooth Loss Linked to Esophageal, Gastric Cancer

TUESDAY, July 21, 2020 (HealthDay News) — Periodontal disease and tooth loss, indicative of oral microbial dysbiosis, are associated with esophageal and gastric adenocarcinoma, according to a research letter published online July 20 in Gut.

Blood Test Can Detect Cancer Before Conventional Diagnosis

TUESDAY, July 21, 2020 (HealthDay News) — A noninvasive blood test based on circulating tumor DNA methylation can detect cancer four years before conventional diagnosis, according to a study published online July 21 in Nature Communications.

Blood Type Not Linked to Progression to Severe COVID-19

TUESDAY, July 21, 2020 (HealthDay News) — For COVID-19 patients, blood type is not associated with the risk for progression to severe disease, according to a study published online July 12 in the Annals of Hematology.

Prenatal Cannabis Exposure Tied to Childhood Sleep Problems

TUESDAY, July 21, 2020 (HealthDay News) — Prenatal cannabis exposure is associated with child sleep outcomes, according to a study published online June 28 in Sleep Health.

Review: In-ICU Mortality for COVID-19 Down to 41.6 Percent

TUESDAY, July 21, 2020 (HealthDay News) — The in-intensive care unit (ICU) mortality from COVID-19 is lower than initially thought, with a combined mortality of 41.6 percent based on 24 studies, according to a review published online June 30 in Anaesthesia.

Demographic, Clinical, Hospital Factors Tied to COVID-19 Death

MONDAY, July 20, 2020 (HealthDay News) — For COVID-19 patients in the intensive care unit (ICU), demographic, clinical, and hospital-level risk factors are associated with death, according to a study published online July 15 in JAMA Internal Medicine.

FDA Issues Warning Letters Regarding Illegal Sales of Vape Products

MONDAY, July 20, 2020 (HealthDay News) — Ten companies have been ordered to remove their flavored disposable e-cigarettes and e-liquid products from the market, the U.S. Food and Drug Administration says.

Pooled Sampling Approved for COVID-19 Test

MONDAY, July 20, 2020 (HealthDay News) — An emergency use authorization (EUA) has been issued for the Quest Diagnostics Quest SARS-CoV-2 real-time reverse transcription polymerase chain reaction test for use with pooled samples containing up to four individual swab specimens collected under observation, the U.S. Food and Drug Administration said Saturday.

Reducing Testing Delay Crucial for Slowing COVID-19 Transmission

MONDAY, July 20, 2020 (HealthDay News) — Minimizing testing delay has the largest impact on reducing onward transmission of COVID-19, according to a study published online July 16 in The Lancet Public Health.

Exercise Helps Prevent High BP Even in Areas of High Air Pollution

MONDAY, July 20, 2020 (HealthDay News) — Regular physical activity (PA) still provides benefit against hypertension even in areas of high air pollution, according to a study published online July 20 in Circulation.

28-Day Mortality in COVID-19 Lower With Dexamethasone

MONDAY, July 20, 2020 (HealthDay News) — Dexamethasone lowers 28-day mortality in patients hospitalized with COVID-19 who are receiving invasive mechanical ventilation or oxygenation alone, according to a study published online July 17 in the New England Journal of Medicine.

Reminder + FIT Test Cost-Effective for Promoting CRC Screening

MONDAY, July 20, 2020 (HealthDay News) — Sending a mailed reminder to promote colorectal cancer (CRC) screening with an included fecal immunochemical testing (FIT) kit is cost-saving for each additional Medicaid enrollee screened compared with just sending a reminder, according to a study published online July 20 in Cancer.

Poll: Most Older Adults Routinely Experience Ageism

MONDAY, July 20, 2020 (HealthDay News) — The majority of older U.S. adults commonly experience ageism in their daily lives, according to a report published online July 13 based on the results of the University of Michigan National Poll on Healthy Aging.

Psychiatric Disorders, Loneliness Common During the Pandemic

MONDAY, July 20, 2020 (HealthDay News) — There are high prevalence rates of general psychiatric disorders and loneliness in the general U.K. population during the COVID-19 pandemic, according to a study published online June 30 in Psychiatry Research.

Ban on Menthol Cigarettes Might Cut Smoking Rates in the U.S.

MONDAY, July 20, 2020 (HealthDay News) — Extending the U.S. cigarette flavor ban to include menthol products could promote smoking cessation and reduce initiation, according to a review published online July 9 in BMC Public Health.

Lymphoma Survivors at Risk for Developing Chronic Kidney Disease

MONDAY, July 20, 2020 (HealthDay News) — Lymphoma survivors are at substantial long-term risk for chronic kidney disease (CKD) development, according to a study published online July 11 in Leukemia & Lymphoma.

Family Medicine Resident Graduates Remain in the Field

THURSDAY, July 16, 2020 (HealthDay News) — Family medicine (FM) residency graduates continue to practice in the field after residency, according to a study published in the July/August issue of the Annals of Family Medicine.

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 13 to 17, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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CDC Will Again Post COVID-19 Hospitalization Data

FRIDAY, July 17, 2020 (HealthDay News) — In a quick policy reversal, the Trump administration on Thursday told the U.S. Centers for Disease Control and Prevention to once again post data about COVID-19 hospitalizations on its website.

CNN Article

Call for ‘Challenge Trials’ to Hasten COVID-19 Vaccine Development

FRIDAY, July 17, 2020 (HealthDay News) — The U.S. government should make immediate preparations for clinical trials in which volunteers are exposed to the new coronavirus to speed development of a vaccine, more than 100 top scientists say in a letter to the U.S. National Institutes of Health.

CNN Article

Lack of Public Education for Using Face Masks Leads to Noncompliance, Experts Warn

FRIDAY, July 17, 2020 (HealthDay News) — A nationwide, coordinated effort is needed to successfully implement widespread wearing of face masks to help slow the spread of COVID-19, according to Robert Brook, M.D., professor of medicine at UCLA and distinguished chair in the health care services program at the RAND Corporation, and May Chu, Ph.D., clinical professor of epidemiology with the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus. They recently spoke with HD Live! about the impending consequences of nonmasking and possible strategies to improve compliance.

Masking of Health Care Workers Cuts SARS-CoV-2 Positivity

FRIDAY, July 17, 2020 (HealthDay News) — Universal masking of health care workers (HCWs) is associated with a reduction in the rate of SARS-CoV-2 positivity, according to a study published online July 14 in the Journal of the American Medical Association.

Variety of Symptoms Reported for COVID-19 Patients

FRIDAY, July 17, 2020 (HealthDay News) — Nearly all symptomatic COVID-19 patients experience fever, cough, or shortness of breath, and a wide variety of other symptoms are reported, according to research published July 17 in the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Social Determinants of Health Linked to Incident Stroke Risk

FRIDAY, July 17, 2020 (HealthDay News) — For adults younger than 75 years, increases in the number of social determinants of health (SDOH) are associated with an increased risk for incident stroke, according to a study published online July 16 in Stroke.

Prediabetes Linked to Increased Risk for Mortality, CVD

FRIDAY, July 17, 2020 (HealthDay News) — Prediabetes is associated with an increased risk for all-cause mortality and cardiovascular disease among the general population and individuals with atherosclerotic cardiovascular disease, according to a meta-analysis published online July 15 in The BMJ.

Exposure to Wildfire Smoke Ups Deaths of Hemodialysis Patients

FRIDAY, July 17, 2020 (HealthDay News) — For patients receiving in-center hemodialysis, exposure to fine particulate matter (PM_2.5) from wildfire is associated with all-cause mortality, according to a study published online July 16 in the Journal of the American Society of Nephrology.

Flu Vaccine Cuts Cardiovascular Mortality in Adults With Diabetes

FRIDAY, July 17, 2020 (HealthDay News) — Influenza vaccination may improve outcomes in patients with diabetes, according to a study published online July 9 in Diabetes Care.

Lopinavir/Ritonavir COVID-19 Treatment Linked to Bradycardia

FRIDAY, July 17, 2020 (HealthDay News) — Lopinavir/ritonavir (LPV/RTV) treatment of COVID-19 is associated with an increased risk for bradycardia, according to a study published online July 9 in Circulation: Arrhythmia and Electrophysiology.

Severe Vasomotor Symptoms at Menopause Linked to CVD Risk

FRIDAY, July 17, 2020 (HealthDay News) — Among women with menopausal vasomotor symptoms (VMS), severity rather than frequency of hot flushes and night sweats is associated with an increased risk for cardiovascular disease (CVD), according to a study published online June 23 in the American Journal of Obstetrics & Gynecology.

LGBT-Friendly Primary Care Improves STD Screening Rates

FRIDAY, July 17, 2020 (HealthDay News) — A quality improvement initiative that enhances lesbian, gay, bisexual, and transgender (LGBT) affirming care also improves screening rates for sexually transmitted diseases, according to a study published in the July/August issue of the Annals of Family Medicine.

Higher SARS-CoV-2 Viral Load Tied to Shorter Symptom Duration

THURSDAY, July 16, 2020 (HealthDay News) — Viral load (VL) of severe acute respiratory syndrome coronavirus 2 is lower in hospitalized patients, and higher VL is associated with a shorter duration of symptoms and hospital stay, according to a study published online July 2 in The American Journal of Pathology.

U.S. Must Spend $75 Billion to Improve COVID-19 Testing, Report Says

THURSDAY, July 16, 2020 (HealthDay News) — The United States faces “an impending disaster” from the coronavirus pandemic and should spend $75 billion to improve its diagnostic testing system for COVID-19, a Rockefeller Foundation report says.

SARS-CoV-2 mRNA-1273 Induces Immune Response

THURSDAY, July 16, 2020 (HealthDay News) — The candidate vaccine mRNA-1273, which encodes the stabilized prefusion severe acute respiratory syndrome coronavirus 2 spike protein, induces immune responses in healthy participants, according to a phase 1 study published online July 14 in the New England Journal of Medicine.

Premature Mortality Dropped With Adoption of Food Guidelines

THURSDAY, July 16, 2020 (HealthDay News) — Adoption of national food-based dietary guidelines (FBDGs) is associated with about a 15 percent reduction in premature mortality, according to a study published online July 15 in The BMJ.

Physical Distancing Interventions Cut Incidence of COVID-19

THURSDAY, July 16, 2020 (HealthDay News) — Physical distancing interventions are associated with a reduced incidence of COVID-19 globally, according to a study published online July 15 in The BMJ.

Ticagrelor-Aspirin Beneficial for Mild-to-Moderate Stroke, TIA

THURSDAY, July 16, 2020 (HealthDay News) — Ticagrelor-aspirin is associated with a reduced risk for the composite of stroke or death within 30 days of mild-to-moderate acute noncardioembolic ischemic stroke or transient ischemic attack (TIA), according to a study published in the July 16 issue of the New England Journal of Medicine.

Nonsmoking Young Adults Less Vulnerable to Severe COVID-19

THURSDAY, July 16, 2020 (HealthDay News) — Nonsmoking young adults have lower medical vulnerability to severe COVID-19 illness, according to a study published online July 13 in the Journal of Adolescent Health.

Impact of COVID-19 Estimated on HIV, TB, Malaria Services

THURSDAY, July 16, 2020 (HealthDay News) — Disruption to services for HIV, tuberculosis, and malaria due to COVID-19 could lead to considerable loss of life in low- and middle-income countries, according to a study published online July 13 in The Lancet Global Health.

CV Risk Factors Linked to Faster Cognitive Decline in Midlife

THURSDAY, July 16, 2020 (HealthDay News) — Cardiovascular risk factors (CVRFs) are associated with accelerated cognitive decline in midlife, according to a study published online July 15 in Neurology.

n3-PUFAs May Protect the Brain From Effects of Air Pollution

WEDNESDAY, July 15, 2020 (HealthDay News) — Long-chain omega 3 polyunsaturated fatty acids (LCn3PUFAs) attenuate the inverse association between fine particular matter (PM_2.5) exposure and white matter volumes, according to a study published online July 15 in Neurology.

Roflumilast Cream Promising for Chronic Plaque Psoriasis

WEDNESDAY, July 15, 2020 (HealthDay News) — Roflumilast cream is superior to placebo vehicle cream for reducing psoriasis severity, according to a study published in the July 16 issue of the New England Journal of Medicine.

CDC Will No Longer Receive Hospitals’ COVID-19 Data

WEDNESDAY, July 15, 2020 (HealthDay News) — U.S. hospitals have been told by the Trump administration to send all COVID-19 information to a central database in Washington, D.C., instead of to the U.S. Centers for Disease Control and Prevention.

The New York Times Article

COVID-19 Vaccine Initiative May Favor Rich Countries

WEDNESDAY, July 15, 2020 (HealthDay News) — A global COVID-19 vaccine initiative has been formed with the objective of ensuring fair distribution of vaccines worldwide, but it may benefit rich countries more than poor nations.

AP News Article

Medication Use Linked to Weight Gain in Postmenopausal Women

WEDNESDAY, July 15, 2020 (HealthDay News) — For postmenopausal women, antidepressants, beta-blockers, and insulin are associated with weight gain over three years, according to a study published online July 15 in Menopause.

Global Population Anticipated to Peak in 2064

WEDNESDAY, July 15, 2020 (HealthDay News) — The global population is anticipated to peak in 2064 and then decline to year 2100, according to a study published online July 14 in The Lancet.

Most U.S. COVID-19-Related Deaths Occur in Medical Facility

WEDNESDAY, July 15, 2020 (HealthDay News) — Most COVID-19-related deaths in the United States occur in a medical facility, according to a study published online July 9 in the Journal of the American Geriatrics Society.

Lymphocytopenia May Predict Greater Severity in COVID-19

WEDNESDAY, July 15, 2020 (HealthDay News) — Lymphocytopenia may be predictive of disease severity in patients with COVID-19, according to a study published online July 10 in the International Journal of Laboratory Hematology.

Delirium Episode Tied to Long-Term Cognitive Decline

WEDNESDAY, July 15, 2020 (HealthDay News) — An episode of delirium is significantly associated with long-term cognitive decline in both surgical and nonsurgical patients, according to a meta-analysis published online July 13 in JAMA Neurology.

Cortisol Profile Linked to Fasting Glucose in Patients With Diabetes

WEDNESDAY, July 15, 2020 (HealthDay News) — For individuals with diabetes, changes in cortisol are positively associated with changes in fasting glucose (FG), according to a study published online July 13 in Psychoneuroendocrinology.

Cardiac CT Can Derive Thoracic Bone Mineral Density, Fracture Risk

WEDNESDAY, July 15, 2020 (HealthDay News) — Cardiac computed tomography (CT) can identify individuals with low bone mineral density (BMD) and increased fracture risk, according to a study published online July 14 in Radiology.

Poor Sleep Patterns May Up Risk for Attacks in Adults With Asthma

WEDNESDAY, July 15, 2020 (HealthDay News) — Too little sleep or too much sleep is tied to more asthma attacks in adults, according to a study recently published in the Annals of Allergy, Asthma & Immunology.

Symptom-Based Testing Not Adequate for Detecting COVID-19

TUESDAY, July 14, 2020 (HealthDay News) — Using symptom-based testing alone is not adequate for identifying COVID-19 cases in long-term care facilities, according to a research letter published online July 14 in JAMA Internal Medicine.

No COVID-19 Deaths Reported in NYC for First Time in Months

TUESDAY, July 14, 2020 (HealthDay News) — New York City — once the COVID-19 epicenter in the United States — has marked a major achievement.

AP News Article

Squirrel With Bubonic Plague Found in Colorado Town

TUESDAY, July 14, 2020 (HealthDay News) — After a squirrel tested positive for the bubonic plague in the town of Morrison in Colorado, health officials are warning that the disease can be contracted by household pets and people.

Layoffs Cost 5.4 Million Americans Their Health Insurance

TUESDAY, July 14, 2020 (HealthDay News) — About 5.4 million Americans lost their health insurance after being laid off between February and May due to the COVID-19 pandemic, a new study shows.

The New York Times Article

Shelter-in-Place Orders Cut Growth Rates of COVID-19 Deaths

TUESDAY, July 14, 2020 (HealthDay News) — Shelter-in-place orders (SIPOs) reduced the daily growth rates of COVID-19 deaths and hospitalizations, according to a report published online July 9 in Health Affairs.

Childhood Maltreatment Tied to Later Cardiovascular Disease

TUESDAY, July 14, 2020 (HealthDay News) — All types of childhood maltreatment are associated with a higher risk for cardiovascular disease (CVD) in both men and women, according to a study published online July 13 in Heart.

Not All Food Sources of Fructose-Containing Sugars Raise Risk for MetS

TUESDAY, July 14, 2020 (HealthDay News) — The adverse association of sugar-sweetened beverages and incident metabolic syndrome (MetS) does not extend to other major food sources of fructose-containing sugars, and yogurt, fruit, 100 percent fruit juice, and mixed fruit juice all have a protective association with MetS, according to a review published online July 9 in JAMA Network Open.

Pap/HPV Cotesting Better for Cervical Cancer Screening in Over 30s

TUESDAY, July 14, 2020 (HealthDay News) — Liquid-based cytology (LBC) and human papillomavirus (HPV) cotesting enhances screening for cervical cancer (CxCa) and precancer among women aged 30 years and older, according to a study published online July 8 in the American Journal of Clinical Pathology.

Outcomes Worse for COVID-19-Linked Ischemic Strokes

TUESDAY, July 14, 2020 (HealthDay News) — COVID-19-associated ischemic strokes are more severe than non-COVID-19 ischemic strokes, with worse functional outcome and increased mortality, according to a study published online July 9 in Stroke.

Hyperglycemia Linked to Higher Mortality in COVID-19 Patients

TUESDAY, July 14, 2020 (HealthDay News) — For COVID-19 patients without a previous diagnosis of diabetes, fasting blood glucose (FBG) ≥7.0 mmol/L is an independent predictor of 28-day mortality, according to a study published online July 10 in Diabetologia.

Commercially Viable Mobile Lung Screening Program Feasible

TUESDAY, July 14, 2020 (HealthDay News) — Developing a commercially viable and financially sound mobile program for lung screening is feasible, according to a study published online July 14 in the Annals of Thoracic Surgery.

Rise Seen in U.S. COVID-19 Deaths

MONDAY, July 13, 2020 (HealthDay News) — Led by states in the South and West, COVID-19 deaths in the United States have started a long-anticipated increase, data show.

AP News Article

Some Hospitals in COVID-19 Hotspots Running Short of Remdesivir

MONDAY, July 13, 2020 (HealthDay News) — Some U.S. hospitals in COVID-19 hotspots are running short of the antiviral drug remdesivir — the only drug authorized by the U.S. Food and Drug Administration to treat the disease — while hospitals in other regions have stocks of the drug that are going unused.

CNN Article

Slow Test Results Hampering U.S. Fight Against COVID-19

MONDAY, July 13, 2020 (HealthDay News) — Test results for the new coronavirus are taking so long that they are doing little to help stop the spread of the virus in the United States, experts say.

Washington Post Article

Plant Protein Intake Linked to Drop in Overall, CVD Mortality

MONDAY, July 13, 2020 (HealthDay News) — Higher plant protein intake is associated with reductions in the risks for overall and cardiovascular disease mortality in men and women, according to a study published online July 13 in JAMA Internal Medicine.

Predicted Albumin-Creatinine Ratio Useful for CKD Screening

MONDAY, July 13, 2020 (HealthDay News) — Predicted albumin-creatinine ratio (ACR) calculated from urine protein-creatinine ratio (PCR) or urine dipstick protein may be useful for chronic kidney disease (CKD) screening, staging, and prognosis, according to research published online July 14 in the Annals of Internal Medicine.

COVID-19 Case Rates, Deaths Considerably Higher in Prisons

MONDAY, July 13, 2020 (HealthDay News) — COVID-19 case rates are substantially higher in prisons than in the U.S. population and are escalating rapidly, according to a research letter published online July 8 in the Journal of the American Medical Association.

COVID-19-Related Symptoms Persist After Recovery

MONDAY, July 13, 2020 (HealthDay News) — Most patients who have recovered from COVID-19 report persistence of at least one symptom, according to a research letter published online July 9 in the Journal of the American Medical Association.

Arthritis Patients Needing to Shelter in Place Require More Support

MONDAY, July 13, 2020 (HealthDay News) — The Norfolk Arthritis Register has released an interim report on the impact of COVID-19 restrictions on people living with inflammatory arthritis who were advised to shelter at home due to increased vulnerability to COVID-19 because of medications.

Baloxavir Protects Household Contacts From Influenza

MONDAY, July 13, 2020 (HealthDay News) — Baloxavir demonstrates postexposure prophylactic efficacy for preventing influenza in household contacts of index patients, according to a study published online July 8 in the New England Journal of Medicine.

Risk for Heart Failure Increased for Women Taking β-Blockers

MONDAY, July 13, 2020 (HealthDay News) — Women taking β-blockers for hypertension have an increased risk for developing heart failure when they present to the hospital with acute coronary syndrome, according to a study published online July 10 in Hypertension.

Policy Guides Medical Marijuana Use at Pediatric Hospital

MONDAY, July 13, 2020 (HealthDay News) — Development of institutional policy and clinical support services is beneficial for pediatric hospitals interested in use of medical marijuana (MMJ), according to a special article published online July 13 in Pediatrics.

Black Individuals at Increased Risk for SARS-CoV-2 Infection

MONDAY, July 13, 2020 (HealthDay News) — Black individuals are at increased risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hospitalization, according to a letter to the editor published online July 9 in the Annals of the American Thoracic Society.

Maternal Allergy, Asthma Traits Up Child Risk in Early Years

MONDAY, July 13, 2020 (HealthDay News) — In early life, maternal history of allergies and asthma confers a stronger effect on a child’s risk for developing the same traits compared with the father’s history, according to a study published online July 7 in Clinical & Experimental Allergy.

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of July 6 to 10, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Gilead Presents Additional Data on Efficacy of Remdesivir for COVID-19

FRIDAY, July 10, 2020 (HealthDay News) — There is more good news on the effectiveness of the antiviral drug remdesivir against COVID-19, according to new clinical trial results from the drug’s maker.

Risk for COVID-19 Increased for Adults Taking PPIs

FRIDAY, July 10, 2020 (HealthDay News) — Adults taking proton pump inhibitors (PPIs) have an increased risk for having a positive COVID-19 test, with evidence of a dose-response relationship, according to a study published online July 7 in preprint format in the American Journal of Gastroenterology.

WHO to Lead Investigation of COVID-19 Pandemic Origins

FRIDAY, July 10, 2020 (HealthDay News) — The World Health Organization will lead an international investigation into the origins of the COVID-19 pandemic in China.

AP News Article
The New York Times Article

Children Seem Not to Be Driving SARS-COV-2 Transmission

FRIDAY, July 10, 2020 (HealthDay News) — Children are mainly infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in familial clusters, suggesting that transmission in schools is likely to be less than expected and that school closures are not necessary, according to a study and accompanying editorial published online July 10 in Pediatrics.

COVID-19 Explored in Kidney Recipients, Hemodialysis Patients

FRIDAY, July 10, 2020 (HealthDay News) — Many outpatient kidney transplant recipients with COVID-19 have symptomatic resolution without requiring hospitalization, and hospitalized COVID-19 patients on hemodialysis have worse outcomes than those without kidney failure, according to two studies recently published in the Clinical Journal of the American Society of Nephrology.

More Than One in Four Seniors Reported Falling in Past Year

FRIDAY, July 10, 2020 (HealthDay News) — In 2018, 27.5 percent of older adults reported falling at least once in the previous year, with 10.2 percent reporting an injury from a fall, according to research published in the July 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Incidence of Takotsubo Cardiomyopathy Up During COVID-19

FRIDAY, July 10, 2020 (HealthDay News) — The incidence of Takotsubo cardiomyopathy has increased during the COVID-19 pandemic, according to a study published online July 9 in JAMA Network Open.

Patterns Changing for Heart Disorder Hospitalizations in Canada

FRIDAY, July 10, 2020 (HealthDay News) — Standardized hospitalization rates declined for coronary artery and vascular disease, heart rhythm disorders, stroke, and heart failure in Canada from 2007 through 2016, according to a study published online July 1 in the Canadian Journal of Cardiology.

Nemolizumab Beats Placebo for Reduction of Pruritus in Eczema

THURSDAY, July 9, 2020 (HealthDay News) — For patients with atopic dermatitis and moderate-to-severe pruritus, nemolizumab results in a greater reduction in pruritus than placebo, according to a study published in the July 9 issue of the New England Journal of Medicine.

COVID-19 Pandemic Exacerbates Mental Health Issues

THURSDAY, July 9, 2020 (HealthDay News) — Just as the physical symptoms of COVID-19 vary among the population, mental health is enduring a variety of effects from the virus as well, according to Don Mordecai, M.D., national mental health and wellness lead at Kaiser Permanente, who recently spoke with HD Live! about the effects of the pandemic on mental health.

Electronic Health Records Fail to Detect Many Medication Errors

THURSDAY, July 9, 2020 (HealthDay News) — There is wide variation in the safety performance of electronic health record (EHR) systems used in U.S. hospitals, according to a study recently published in JAMA Network Open.

Sick Days Up for Some Essential Workers During COVID-19

THURSDAY, July 9, 2020 (HealthDay News) — Increases in health-related workplace absenteeism were seen in April 2020 in personal care and service, health care support, and production occupations, according to research published in the July 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Higher Rates of Pain, Bleeding Found With Essure Birth Control Device

THURSDAY, July 9, 2020 (HealthDay News) — The permanent birth control device Essure is associated with higher rates of chronic lower abdominal or pelvic pain and abnormal uterine bleeding compared with tubal ligation, according to interim results of a postmarket study ordered by the U.S. Food and Drug Administration.

AP News Article

Half of Individuals With MI at Age 50 or Younger Are Smokers

THURSDAY, July 9, 2020 (HealthDay News) — About half of individuals who experience a myocardial infarction at 50 years or younger are smokers, and among these individuals, smoking cessation is associated with a reduced risk for all-cause and cardiovascular mortality, according to a study published online July 8 in JAMA Network Open.

Physically Demanding Jobs May Raise Risk for Knee Osteoarthritis

THURSDAY, July 9, 2020 (HealthDay News) — The odds of knee osteoarthritis (OA) are increased in association with heavy physically demanding occupations and occupational activities, according to a review published online July 7 in Arthritis Care & Research.

CDC Updates Info on COVID-19 Cases at Meat, Poultry Processing Facilities

THURSDAY, July 9, 2020 (HealthDay News) — COVID-19 was confirmed in 16,233 workers in 239 meat and poultry processing facilities in 23 states through May 31, 2020, according to research published in the July 7 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Multifactor Program Does Not Cut Serious Fall Injuries in Elderly

THURSDAY, July 9, 2020 (HealthDay News) — A nurse-administered multifactorial intervention does not result in a significantly lower rate of first adjudicated serious fall injury among older adults at increased risk for fall injuries, according to a study published in the July 9 issue of the New England Journal of Medicine.

Higher Vitamin C, Carotenoid Intake May Lower Risk for T2DM

THURSDAY, July 9, 2020 (HealthDay News) — Higher intakes of vitamin C and carotenoids, as well as total whole grains, are associated with a lower risk for type 2 diabetes, according to two studies published online July 8 in The BMJ.

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2008 to 2018 Saw Increase in Shingles Vaccination in Over 60s

THURSDAY, July 9, 2020 (HealthDay News) — From 2008 to 2018, there was an increase in shingles vaccination among adults aged 60 years and older, with demographic, socioeconomic, and geographic variations in vaccination rates, according to a July data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

11 Dengue Fever Cases Confirmed in Florida Keys

WEDNESDAY, July 8, 2020 (HealthDay News) — Confirmation of an 11th case of dengue fever in the Florida Keys was announced Tuesday by state health officials.

AP News Article

Upadacitinib Beats Methotrexate in Early Rheumatoid Arthritis

WEDNESDAY, July 8, 2020 (HealthDay News) — Upadacitinib monotherapy results in improved outcomes versus methotrexate for patients with predominantly early rheumatoid arthritis, according to a study published online July 8 in Arthritis & Rheumatology.

U.S. Launches Suicide Prevention Campaign

WEDNESDAY, July 8, 2020 (HealthDay News) — A national campaign to prevent suicide has been launched by the U.S. government.

AP News Article

February to March 2020 Saw Surge in Hydroxychloroquine Rx

WEDNESDAY, July 8, 2020 (HealthDay News) — From February to March 2020, there was a considerable increase in the number of patients receiving outpatient prescriptions for hydroxychloroquine, chloroquine, and azithromycin, according to a research letter published online July 6 in JAMA Internal Medicine.

Statin Use May Cut All-Cause, CVD Mortality in Those 75 and Older

WEDNESDAY, July 8, 2020 (HealthDay News) — In U.S. veterans aged 75 years and older, statin use is associated with reduced all-cause and cardiovascular mortality, according to a study published in the July 7 issue of the Journal of the American Medical Association.

Dairy Does Not Protect Against Bone Loss During Menopause Transition

WEDNESDAY, July 8, 2020 (HealthDay News) — Dairy intake is not associated with improvements in bone mineral density or risk for fractures in women transitioning to menopause, according to a study recently published in Menopause.

Rising Number of People Report Anxiety, Depression During COVID-19

WEDNESDAY, July 8, 2020 (HealthDay News) — New evidence shows that depression and anxiety are increasing as a result of the COVID-19 pandemic, according to the results of a survey released by Mental Health America (MHA).

Interruption of Sitting May Cut Acute Postprandial Response

WEDNESDAY, July 8, 2020 (HealthDay News) — When individuals interrupt prolonged sitting with bouts of light physical activity, postprandial insulin and glucose levels are reduced, according to a study published in the June issue of Medicine & Science in Sports & Exercise.

Suspected Plague Case Reported in China

TUESDAY, July 7, 2020 (HealthDay News) — A suspected bubonic plague case in the Bayannur district of the Inner Mongolia Autonomous Region of China has been reported by local officials.

CBS News Article

COVID-19 Antibody Cocktail Begins Late-Stage Human Trials

TUESDAY, July 7, 2020 (HealthDay News) — Late-stage human trials to assess whether a double antibody cocktail can prevent and treat COVID-19 infection have started, biotechnology company Regeneron said Monday.

CNN Article

Company Gets $1.6 Billion From U.S. Government for COVID-19 Vaccine

TUESDAY, July 7, 2020 (HealthDay News) — Vaccine maker Novavax will receive $1.6 billion from the U.S. government to provide 100 million doses of a COVID-19 vaccine by early 2021, the Maryland-based company said Monday.

The New York Times Article

USPSTF Advises Annual Low-Dose CT Lung Screening for High-Risk Individuals

TUESDAY, July 7, 2020 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends annual low-dose computed tomography (LDCT) screening for people aged 50 to 80 years at high lung cancer risk due to smoking history. These recommendations form the basis of a draft recommendation statement, published online July 7 by the USPSTF.

Draft Evidence Review
Draft Recommendation Statement
Comment on Recommendation Statement

Acute Ischemic Stroke Risk Higher With COVID-19 Than Influenza

TUESDAY, July 7, 2020 (HealthDay News) — Patients with COVID-19 appear to have a heightened risk for acute ischemic stroke compared with patients with influenza, according to a study published online July 2 in JAMA Neurology.

Oral Corticosteroid Bursts Carry Risk for Severe Adverse Events

TUESDAY, July 7, 2020 (HealthDay News) — Prescriptions for oral steroid bursts are associated with a 1.8- to 2.4-fold increased risk for severe adverse events within the first month after initiation of drug therapy, according to a study published online July 7 in the Annals of Internal Medicine.

Early Breast Cancer Screening Benefits Childhood Cancer Survivors

TUESDAY, July 7, 2020 (HealthDay News) — For childhood cancer survivors, early initiation of breast cancer screening with magnetic resonance imaging (MRI) may reduce breast cancer mortality by more than half, according to a study published online July 7 in the Annals of Internal Medicine.

Social Distancing Effective for Mitigating COVID-19 Spread

TUESDAY, July 7, 2020 (HealthDay News) — Social distancing is one of the main measures to combat COVID-19 spread, according to a study published online July 1 in The Lancet Infectious Diseases.

Review: Pre/Probiotics May Be Useful for Depression, Anxiety

TUESDAY, July 7, 2020 (HealthDay News) — Pre/probiotic therapy may be useful for patients with depression and/or anxiety disorders, according to a review published online July 6 in BMJ Nutrition, Prevention & Health.

Genetic Variant Identified for Adult-Onset Hearing Loss

TUESDAY, July 7, 2020 (HealthDay News) — An inherited form of adult-onset hearing loss is relatively common, according to a study published online July 6 in the Journal of Medical Genetics.

Excessive Sugar Tied to Fat Deposits Around Heart, Other Organs

TUESDAY, July 7, 2020 (HealthDay News) — Long-term intake of added sugar and sugar-sweetened beverages is associated with higher pericardial adipose tissue, visceral adipose tissue, and subcutaneous adipose tissue volumes, according to a study published online June 28 in the European Journal of Preventive Cardiology.

Complementary, Alternative Medicine Use Increasing for MS

TUESDAY, July 7, 2020 (HealthDay News) — For people with multiple sclerosis (pwMS), there has been an increase in use of complementary and alternative medicine (CAM), according to a study published in the June issue of Multiple Sclerosis and Related Disorders.

Chilblains in Recent Case Series Not Tied to COVID-19 Infection

TUESDAY, July 7, 2020 (HealthDay News) — In a case series of 31 patients, published online June 25 in JAMA Dermatology, chilblains did not appear to be directly associated with COVID-19.

Black Race Linked to Increased MACE Risk After PCI

MONDAY, July 6, 2020 (HealthDay News) — For patients undergoing percutaneous coronary intervention, black race is associated with an increased risk for major adverse cardiac events (MACE), according to research published online July 6 in JACC: Cardiovascular Interventions.

Scientists Say New Coronavirus Can Linger in Indoor Air

MONDAY, July 6, 2020 (HealthDay News) — The new coronavirus can linger in indoor air and infect people, 239 scientists in 32 countries say in an open letter to the World Health Organization that challenges the WHO’s position on how the virus is spread.

The New York Times Article

FDA Warns About Hand Sanitizers With Methanol

MONDAY, July 6, 2020 (HealthDay News) — A warning about hand sanitizer products that contain methanol (wood alcohol), a substance often used to create fuel and antifreeze, has been issued by the U.S. Food and Drug Administration.

Major Medical Groups Urge Americans to Wear Face Masks

MONDAY, July 6, 2020 (HealthDay News) — Three major medical groups are urging Americans to wear face masks, wash their hands, and practice social distancing as COVID-19 cases continue to surge in the United States.

Fight Against COVID-19 Threatens Progress Against Other Diseases

MONDAY, July 6, 2020 (HealthDay News) — Decades of progress against HIV, tuberculosis, malaria, and other diseases worldwide are threatened by the diversion of resources on the COVID-19 pandemic, the International AIDS Society says in a report to be published this week.

CNN Article

Medicaid Expansion Contributing to Earlier Cancer Diagnosis

MONDAY, July 6, 2020 (HealthDay News) — Among low-income adults, the odds of being diagnosed with metastatic breast, cervical, colorectal, or lung cancers decreased following Medicaid expansion in Ohio, according to a study published online July 6 in Cancer.

Most Women Unaware of Breast Implant-Related Lymphoma

MONDAY, July 6, 2020 (HealthDay News) — Only a minority of American women have heard of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) and understand its association with breast implants, according to a study published in the July issue of Plastic and Reconstructive Surgery.

Decline in REM Sleep Linked to Increased Mortality

MONDAY, July 6, 2020 (HealthDay News) — A reduction in the percentage of rapid eye movement (REM) sleep is associated with increased mortality in middle-aged and older adults, according to a study published online July 6 in JAMA Neurology.

Health Expenditures Considerable for Asthma, COPD in U.S. Workers

MONDAY, July 6, 2020 (HealthDay News) — The annualized total medical expenditures for asthma and chronic obstructive pulmonary disease (COPD) are $7 billion and $5 billion among U.S. workers, respectively, according to research published in the July 3 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

CRC Risk Down With ACEi, Angiotensin Receptor Blocker Use

MONDAY, July 6, 2020 (HealthDay News) — The use of angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers is associated with a lower risk for colorectal cancer that develops within three years after index colonoscopy, according to a study published online July 6 in Hypertension.

Outcomes Similar for COVID-19 in Patients With, Without HIV

MONDAY, July 6, 2020 (HealthDay News) — Persons with HIV (PWH) hospitalized with COVID-19 have similar outcomes to demographically matched patients without HIV, according to a study published online June 28 in Clinical Infectious Diseases.

Most Using Online COVID-19 Tool Report Mild, Moderate Symptoms

MONDAY, July 6, 2020 (HealthDay News) — The majority of individuals using an online COVID-19 self-assessment tool report mild or moderate symptoms possibly associated with COVID-19, according to research published online June 15 in the Journal of General Internal Medicine.

Thousands of Heat-Related Deaths Occur Each Year in the U.S.

THURSDAY, July 2, 2020 (HealthDay News) — Between 1997 and 2006, 0.44 percent of U.S. deaths were attributable to heat, according to a study published in the June issue of Environmental Epidemiology.

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 29 to July 3, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Some Say Allow Family Access to Dying Patients With COVID-19

THURSDAY, July 2, 2020 (HealthDay News) — Allowing adult family member presence at the bedside of dying patients during COVID-19 is feasible, and could have multiple benefits, according to an editorial published online June 8 in Intensive Care Medicine.

Point-Prevalence Surveys in SNFs Help Cut COVID-19 Transmission

THURSDAY, July 2, 2020 (HealthDay News) — Conducting point-prevalence surveys in skilled nursing facilities (SNFs) can inform cohorting and infection prevention and control (IPC) activities to reduce transmission, according to research published in the July 1 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Mortality Higher From AKI Versus Kidney Failure From Other Causes

THURSDAY, July 2, 2020 (HealthDay News) — Kidney failure resulting from acute kidney injury (AKI) leads to a higher risk of death in the first six months compared to kidney failure from diabetes or other causes, according to a study published online June 17 in the Clinical Journal of the American Society of Nephrology.

HDHPs Up Disparities in Access to Care Among Cancer Survivors

THURSDAY, July 2, 2020 (HealthDay News) — For cancer survivors, high-deductible health plans (HDHPs) are associated with cost-related barriers to care, and these barriers are greater for black cancer survivors, according to a study published online June 24 in JAMA Network Open.

Evidence Poor for Accuracy of Serological Tests for COVID-19

THURSDAY, July 2, 2020 (HealthDay News) — Existing evidence on the diagnostic accuracy of serological tests for COVID-19 is characterized by high risks of bias and heterogeneity, according to a review and meta-analysis published online July 1 in The BMJ.

Treatment Up for U.S. Adults Who Screen Positive for Depression

THURSDAY, July 2, 2020 (HealthDay News) — From 2007 to 2016, there was an increase in the proportion of adults who screened positive for depression receiving any treatment, according to a research letter published online July 1 in JAMA Psychiatry.

Mortality Risk Down With Meeting Recommended Exercise Levels

THURSDAY, July 2, 2020 (HealthDay News) — The risk of all-cause and cause-specific mortality is reduced for adults who engage in leisure time aerobic and muscle strengthening activities at levels recommended by the 2018 physical activity guidelines, according to a study published online July 1 in The BMJ.

Low Physical Function May Up Bone Loss After Hip Fracture

THURSDAY, July 2, 2020 (HealthDay News) — Older patients with low physical function and lower lean body mass (LBM) may be at risk for greater decline in tibia bone properties during the first year after hip fracture, according to a study published online June 9 in BMC Musculoskeletal Disorders.

Roughly 2 Million Americans Buy Prescriptions From Outside the Country

THURSDAY, July 2, 2020 (HealthDay News) — An estimated 1.5 percent of American adults purchase prescription medication from outside of the United States to save money, according to a study published online June 24 in JAMA Network Open.

U.S. Grab of Only COVID-19 Treatment Outrages Health Experts

WEDNESDAY, July 1, 2020 (HealthDay News) — The United States’ deal with Gilead Sciences to scoop up nearly all of the world’s supply of the only drug licensed to treat COVID-19 has outraged health experts.

AP News Article

Promising Results for Experimental COVID-19 Vaccine in Early Testing

WEDNESDAY, July 1, 2020 (HealthDay News) — An experimental COVID-19 vaccine yielded promising results in early testing, according to Pfizer and its German partner BioNTech.

AP News Article

COVID-19-Related Death Count Likely Higher Than Official Tallies

WEDNESDAY, July 1, 2020 (HealthDay News) — Official COVID-19 death tallies underestimate the full increase in deaths associated with the pandemic in many states, according to a study published online July 1 in JAMA Internal Medicine.

Early Childhood Sleep Problems Tied to Later Mental Health Issues

WEDNESDAY, July 1, 2020 (HealthDay News) — Some behavioral sleep problems in early childhood are associated with the onset of mental health symptoms during early adolescence, according to a study published online July 1 in JAMA Psychiatry.

2005 to 2016 Saw Increase in Skeletal Muscle Relaxant Use

WEDNESDAY, July 1, 2020 (HealthDay News) — From 2005 to 2016, skeletal muscle relaxant (SMR) use increased in the United States, according to a study published online June 24 in JAMA Network Open.

Model Estimates Herd Immunity Threshold for COVID-19

WEDNESDAY, July 1, 2020 (HealthDay News) — A mathematical model shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease-induced herd immunity level may be lower than the classical model assuming homogenous immunization, according to a report published online June 23 in Science.

Social Vulnerability Linked to COVID-19 Diagnosis, Death

WEDNESDAY, July 1, 2020 (HealthDay News) — Social vulnerability is associated with increased risk of COVID-19 diagnosis and death, according to research published online June 23 in the Journal of General Internal Medicine.

Some Kidney Disease-Related Terms Cause Patient Distress

WEDNESDAY, July 1, 2020 (HealthDay News) — The obscurity and imprecision of terms related to chronic kidney disease (CKD) can be distressing for patients, according to a study published online June 25 in the Clinical Journal of the American Society of Nephrology.

Genetic Tests May Differ in Their Interpretation of Certain Variants

WEDNESDAY, July 1, 2020 (HealthDay News) — Different genetic test interpretations have been identified for genetic variants, and some of these can impact patient management, according to a research letter published online June 30 in the Annals of Internal Medicine.

Increased Body Weight, Obesity Linked to Dementia Incidence

WEDNESDAY, July 1, 2020 (HealthDay News) — Having increased body weight or abdominal obesity is associated with increased incidence of dementia, according to a study published online June 23 in the International Journal of Epidemiology.

Elastomeric Mask Program Saves Money

WEDNESDAY, July 1, 2020 (HealthDay News) — Establishing an elastomeric mask program is feasible and less expensive than programs focused on reusing and disinfecting disposable N95 masks, according to a report published online June 11 in the Journal of the American College of Surgeons.

Artificial Intelligence Provides Benefit for Cervical Cancer Screening

WEDNESDAY, July 1, 2020 (HealthDay News) — For women undergoing human papillomavirus (HPV)-based cervical cancer screening, automated evaluation of p16/Ki-67 dual-stained (DS) slides reduces the number of colposcopies compared with current standards, according to a study published online June 25 in the Journal of the National Cancer Institute.

Multiple Healthy Eating Patterns May Be Able to Lower CVD Risk

WEDNESDAY, July 1, 2020 (HealthDay News) — Greater adherence to healthy eating patterns is consistently associated with lower risk of cardiovascular disease (CVD), according to a study published online June 15 in JAMA Internal Medicine.

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