Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for July 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Burnout Symptoms May Up Racial Bias Among Resident Physicians
WEDNESDAY, July 31, 2019 (HealthDay News) — Symptoms of burnout seem to be associated with greater explicit and implicit racial bias among resident physicians, according to a study published online July 26 in JAMA Network Open.
Risk for Allergy Development Increased After Gastric Acid Inhibitor Use
WEDNESDAY, July 31, 2019 (HealthDay News) — Patients receiving gastric acid inhibitors have an increase in prescriptions of anti-allergic drugs, according to a study published online July 30 in Nature Communications.
$70 Million Settlement Reached in Generic Drug Delay Case
TUESDAY, July 30, 2019 (HealthDay News) — Three drug companies will pay a total of nearly $70 million to California to settle charges of delaying the sale of generic drugs to keep brand-name drug prices high, the state’s attorney general said Monday.
AP News Article
National Norms Developed for Assessing Medical School Empathy
TUESDAY, July 30, 2019 (HealthDay News) — National norms have been developed for assessing empathy among men and women at different levels of medical school education, according to a study published in the August issue of the Journal of the American Osteopathic Association.
Substantial Costs Attributable to Hospital-Acquired C. Difficile
MONDAY, July 29, 2019 (HealthDay News) — Hospital-acquired Clostridioides difficile infection (HA-CDI) is associated with substantial attributable costs, according to a study published online July 25 in Infection Control & Hospital Epidemiology.
FDA: Blood Clot, Death Risk Up With Higher Dose of Tofacitinib
FRIDAY, July 26, 2019 (HealthDay News) — New warnings about an increased risk of thrombosis and of death among ulcerative colitis patients taking the 10 mg twice daily dose of the drug tofacitinib (Xeljanz, Xeljanz XR) have been issued by the U.S. Food and Drug Administration.
Bariatric Surgery Up in Patients With End-Stage Kidney Disease
THURSDAY, July 25, 2019 (HealthDay News) — For patients with end-stage kidney disease (ESKD), there has been an increase in bariatric surgery, with proportional use of laparoscopic sleeve gastrectomy increasing, according to a study published online July 25 in the Clinical Journal of the American Society of Nephrology.
Higher Fasting Plasma Glucose May Up Pancreatic Cancer Risk
THURSDAY, July 25, 2019 (HealthDay News) — The incidence rate of pancreatic cancer increases with rising fasting blood glucose levels, even within the normal range, according to a study published online July 24 in the Journal of Clinical Endocrinology & Metabolism.
Periop Diabetic Ketoacidosis Seen in Patients on SGLT2 Inhibitors
WEDNESDAY, July 24, 2019 (HealthDay News) — Sodium-glucose cotransporter-2 inhibitor (SGLT2i)-associated diabetic ketoacidosis (DKA) may occur after surgery even in patients with normal or near-normal blood glucose levels, according to a review published in the July issue of the British Journal of Anaesthesia.
Senate Bill Would Reduce Drug Costs for Seniors
TUESDAY, July 23, 2019 (HealthDay News) — A bill to reduce prescription drug costs for millions of Medicare recipients and lower federal and state health costs has been introduced by two U.S. senators.
AP News Article
T2DM Increases Gastric Cancer Risk After H. Pylori Eradication
TUESDAY, July 23, 2019 (HealthDay News) — Type 2 diabetes mellitus increases the risk for gastric cancer after treatment for Helicobacter pylori infection, according to a study published online July 11 in Diabetes Care.
Proportion of CRC Diagnoses Increased in Adults Younger Than 50
MONDAY, July 22, 2019 (HealthDay News) — From 2004 to 2015, there was an increase in the proportion of persons diagnosed with colorectal cancer (CRC) at an age younger than 50 years in the United States, according to a study published online July 22 in Cancer.
Rates of Anal Cancer Precursors High in Women Living With HIV
MONDAY, July 22, 2019 (HealthDay News) — The prevalence of anal high-grade squamous intraepithelial lesions (HSILs), which precede anal cancer, is high among women living with HIV (WLHIV) in the United States, according to a study published online July 11 in Clinical Infectious Diseases.
Novel Test Accurately Identifies Precancerous Pancreatic Cysts
THURSDAY, July 18, 2019 (HealthDay News) — A comprehensive test is more accurate than conventional clinical and imaging criteria for identifying precancerous pancreatic cysts, according to a study published online July 17 in Science Translational Medicine.
About One in 20 Patients Exposed to Preventable Harm
THURSDAY, July 18, 2019 (HealthDay News) — The pooled prevalence of preventable patient harm is 6 percent across a range of medical settings globally, according to a review published online July 17 in The BMJ.
Continuous Anticoagulants + Cold Snare Polypectomy Noninferior
WEDNESDAY, July 17, 2019 (HealthDay News) — For patients with subcentimeter colorectal polyps receiving oral anticoagulants, continuous administration of anticoagulants (CA) with cold snare polypectomy (CSP) is noninferior to periprocedural heparin bridging (HB) with hot snare polypectomy (HSP) for polypectomy-related major bleeding, according to a study published online July 16 in the Annals of Internal Medicine.
Colonoscopy Rates Increased in Those Aged 45 to 54 Years
TUESDAY, July 16, 2019 (HealthDay News) — From 2000 to 2015, colonoscopy rates increased among those aged 45 to 54 years, while colorectal cancer incidence increased among those aged 40 to 54 years, according to a study published online July 11 in the Journal of Medical Screening.
Superior Outcomes Seen for Living Donor Liver Transplant
TUESDAY, July 16, 2019 (HealthDay News) — Living donor liver transplant (LDLT) offers superior outcomes and less resource utilization over deceased donor liver transplant (DDLT), according to research published online July 10 in the Annals of Surgery.
Etanercept Tx for Autoimmune Disease May Up Risk for IBD
MONDAY, July 15, 2019 (HealthDay News) — Patients with autoimmune diseases have an increased risk for being diagnosed with Crohn disease (CD) or ulcerative colitis (UC) while under treatment with etanercept, according to a study published online July 2 in Alimentary Pharmacology and Therapeutics.
State-Level Variation Noted in Economic Burden of Cancer
FRIDAY, July 12, 2019 (HealthDay News) — There is considerable state-level variation in the economic burden of cancer, according to a study published online July 3 in JAMA Oncology.
Serious Misdiagnosis-Related Harms Mostly Due to ‘Big Three’
FRIDAY, July 12, 2019 (HealthDay News) — Vascular events, infections, and cancers account for about three-quarters of serious misdiagnosis-related harms, according to a study published online July 11 in Diagnosis.
Capping Work Hours in Residency Does Not Impact Outcomes Later
THURSDAY, July 11, 2019 (HealthDay News) — Exposure of U.S. physicians to work-hour reforms during residency training is not associated with post-training differences in patient mortality, readmissions, or costs of care, according to a study published online July 11 in The BMJ.
Medicare Drug Rebate Plan Withdrawn by Trump Administration
THURSDAY, July 11, 2019 (HealthDay News) — A plan to let Medicare patients receive rebates that drug companies currently pay to insurers and middlemen has been withdrawn by the Trump administration.
AP News Article
Negative Cognitive Bias May Be Key to Depression in Active IBD
THURSDAY, July 11, 2019 (HealthDay News) — Biases in emotional processing may contribute to depression in individuals with inflammatory bowel disease (IBD) who have active disease, according to a study published online July 2 in Neurogastroenterology & Motility.
Health Care Professionals Exhibit Gender Bias
THURSDAY, July 11, 2019 (HealthDay News) — Survey results show that health care professionals have implicit and explicit gender bias, according to a study published online July 5 in JAMA Network Open.
High Sodium, High Fiber Both Increase Bloated Feeling
WEDNESDAY, July 10, 2019 (HealthDay News) — Both high-sodium and high-fiber diets increase patient reports of bloating, according to a study published in the July issue of the American Journal of Gastroenterology.
Rule Requiring Drug Prices in TV Ads Blocked by Judge
TUESDAY, July 9, 2019 (HealthDay News) — A Trump administration rule to force pharmaceutical companies to disclose the list prices of their drugs in television ads was blocked Monday by a federal judge.
The New York Times Article
EHR System-Generated In-Basket Messages Linked to Burnout
TUESDAY, July 9, 2019 (HealthDay News) — Receipt of more than the average number of electronic health record (EHR) system-generated in-basket messages is associated with an increased probability of physician burnout, according to a study published in the July 1 issue of Health Affairs.
History of Liver Disease Does Not Impact Efficacy of Edoxaban
TUESDAY, July 9, 2019 (HealthDay News) — For patients with atrial fibrillation (AF), the efficacy and safety of edoxaban versus warfarin is not altered with a history of liver disease, according to a study published in the July 16 issue of the Journal of the American College of Cardiology.
Environment May Be Main Factor in Norway’s Obesity Epidemic
TUESDAY, July 9, 2019 (HealthDay News) — Environment most likely remains the main contributor to the obesity epidemic in Norway, given that body mass index (BMI) has increased for both genetically predisposed and nonpredisposed people since the 1960s, according to a study published online July 3 in The BMJ.
Early Warning Signs May Predate Eating Disorder Onset
MONDAY, July 8, 2019 (HealthDay News) — Early warning signs may help providers identify eating disorders earlier, according to a study published online July 1 in the British Journal of Psychiatry.
Considerable Number of Patients Receive Surprise Hospital Charges
TUESDAY, July 2, 2019 (HealthDay News) — Eighteen percent of all emergency department visits and 16 percent of in-network hospital stays have at least one out-of-network charge, according to a report published June 20 by the Kaiser Family Foundation.
Guidance Issued for Management of Fontan Circulation
TUESDAY, July 2, 2019 (HealthDay News) — A scientific statement with recommendations for follow-up care in patients with Fontan circulation surviving into adulthood was published online July 1 in Circulation.
Metformin May Cut Mortality Risk in Post-Pancreatitis Diabetes
MONDAY, July 1, 2019 (HealthDay News) — Metformin use may promote a survival benefit in individuals with post-pancreatitis diabetes mellitus (PPDM), but not pancreatic cancer-related diabetes (PCRD), according to a study published online June 21 in Diabetes Care.
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