Home OBGYN and Women's Health January 2019 Briefing – OBGYN & Women’s Health

January 2019 Briefing – OBGYN & Women’s Health

Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women’s Health for January 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Long-Term Incidence of A-Fib Increased in Women With Breast Cancer

THURSDAY, Jan. 31, 2019 (HealthDay News) — Women with breast cancer have an increased long-term incidence of atrial fibrillation (AF), according to a study published online Jan. 28 in Heart Rhythm.

Rising Temps May Up Burden of Congenital Heart Disease in U.S.

THURSDAY, Jan. 31, 2019 (HealthDay News) — Projected increases in maternal heat exposure may result in increased congenital heart defect (CHD) burden, according to a study published online Jan. 30 in the Journal of the American Heart Association.

AHA: Nearly Half of U.S. Adults Have Cardiovascular Disease

THURSDAY, Jan. 31, 2019 (HealthDay News) — The prevalence of cardiovascular disease (CVD) is 48.0 percent in adults in the United States based on 2013 to 2016 data, according to a report published online Jan. 31 in Circulation.

Small Increase in HbA1c Seen With Switch to Human Insulin in T2DM

THURSDAY, Jan. 31, 2019 (HealthDay News) — Switching from analogue to human insulin is associated with a small increase in hemoglobin A1c (HbA1c) levels, according to a study published in the Jan. 29 issue of the Journal of the American Medical Association.

Management of MS in Pregnancy Reviewed in U.K. Guideline

THURSDAY, Jan. 31, 2019 (HealthDay News) — It is important to discuss family planning and pregnancy proactively in women of childbearing age who have multiple sclerosis (MS), according to a review published online Jan. 5 in Practical Neurology.

More High-Value Care Associated With Receipt of Primary Care

THURSDAY, Jan. 31, 2019 (HealthDay News) — Receipt of primary care is associated with significantly more high-value care, slightly more low-value care, and a better health care experience, according to a study published online Jan. 28 in JAMA Internal Medicine.

FDA Receives an ‘F’ in Tobacco Prevention Report Card

WEDNESDAY, Jan. 30, 2019 (HealthDay News) — The U.S. Food and Drug Administration was given an “F” in a new American Lung Association report card evaluating tobacco prevention programs.

CNN Article
State of Tobacco Control

Undisturbed Maternal Sleep Tied to Higher Risk for Late Stillbirth

WEDNESDAY, Jan. 30, 2019 (HealthDay News) — Long periods of undisturbed sleep during pregnancy are associated with late stillbirth, according to a study published online Jan. 18 in Birth.

New Guidelines Introduced for Inflammatory Bowel Disease in Pregnancy

TUESDAY, Jan. 29, 2019 (HealthDay News) — The American Gastroenterological Association (AGA) report, Inflammatory Bowel Disease (IBD) in Pregnancy Clinical Care Pathway, was published online Jan. 15 in Gastroenterology.

Few Patients With Type 1 Diabetes Meeting HbA1c Goals

TUESDAY, Jan. 29, 2019 (HealthDay News) — Only one in five children and adults with type 1 diabetes (T1D) in the United States achieve American Diabetes Association (ADA) goals for glycated hemoglobin (HbA1c), according to a study published online Jan. 18 in Diabetes Technology & Therapeutics.

Evidence Lacking for Benefit of Surgery for Vertebral Fractures

MONDAY, Jan. 28, 2019 (HealthDay News) — Surgical procedures do not appear to provide significant benefit for patients with vertebral fractures (VF), according to a second American Society for Bone and Mineral Research Task Force report published in the January issue of the Journal of Bone and Mineral Research.

Adverse Birth Outcomes Up With Medically Assisted Reproduction

MONDAY, Jan. 28, 2019 (HealthDay News) — Children born by medically assisted reproduction have an increased risk for adverse birth outcomes; however, the increased risk appears to be attributable to other factors, according to a study published online Jan. 14 in The Lancet.

Report IDs Areas Lacking Good Practice in Health Tech Assessment

FRIDAY, Jan. 25, 2019 (HealthDay News) — In a report published in the January issue of Value in Health, an ISPOR–The Professional Society for Health Economics and Outcomes Research working group indicates the lack of good practices in three areas of health technology assessment (HTA).

Many Teens Not Up to Date on HPV Vaccination

FRIDAY, Jan. 25, 2019 (HealthDay News) — Many adolescents do not complete human papillomavirus (HPV) vaccination before turning 13 or 15 years old, according to a report published online Jan. 17 in the Journal of Infectious Diseases.

Fried Chicken, Fish Linked to All-Cause, Cardiovascular Death

THURSDAY, Jan. 24, 2019 (HealthDay News) — Among postmenopausal women, fried food consumption, especially fried chicken and fish/shellfish, is associated with an increased risk for all-cause and cardiovascular mortality, according to a study published online Jan. 23 in The BMJ.

Initiative Tied to Decreased Racial Inequity in Breastfeeding

THURSDAY, Jan. 24, 2019 (HealthDay News) — A hospital-based initiative in Southern states is associated with increases in breastfeeding rates among African-American infants, according to a study published online Jan. 18 in Pediatrics.

Time to Breast Cancer Surgery Delayed for Non-Hispanic Blacks

THURSDAY, Jan. 24, 2019 (HealthDay News) — The time to surgery (TTS) after a breast cancer diagnosis is delayed for non-Hispanic black (NHB) versus non-Hispanic white (NHW) women, according to a study published online Jan. 23 in JAMA Surgery.

Endometrial Scratching Does Not Increase Live Birth Rate in IVF

WEDNESDAY, Jan. 23, 2019 (HealthDay News) — For women undergoing in vitro fertilization (IVF), endometrial scratching by pipelle biopsy between day 3 of the cycle preceding the embryo-transfer cycle and day 3 of the embryo-transfer cycle, does not result in a higher rate of live birth, according to a study published in the Jan. 24 issue of the New England Journal of Medicine.

Herd Protection Seen With 4-Valent HPV Vaccination

WEDNESDAY, Jan. 23, 2019 (HealthDay News) — From 2006 to 2017, there was a decrease in 4-valent vaccine-type human papillomavirus (HPV) detection among vaccinated and unvaccinated women, according to a study published online Jan. 22 in Pediatrics.

Marketing of Opioids Linked to Increased OD Mortality

WEDNESDAY, Jan. 23, 2019 (HealthDay News) — Marketing of opioids to physicians is associated with increased mortality from opioid overdoses, according to a study published online Jan. 18 in JAMA Network Open.

Medical Cannabis Decisions Being Made by Users, Not Doctors

TUESDAY, Jan. 22, 2019 (HealthDay News) — Many patients use medical cannabis without their mainstream health care provider’s knowledge, and further, they self-adjust their pharmaceutical use in response to cannabis use, according to a study published online Jan. 8 in the Journal of Psychoactive Drugs.

CDC: Slight Hike in Prevalence of Gastroschisis Since 2006-2010

TUESDAY, Jan. 22, 2019 (HealthDay News) — Over time, the prevalence of gastroschisis has increased, with more babies born with gastroschisis in areas with high and medium versus low opioid prescription rates, according to research published in the Jan. 18 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

CDC: Opioid Prescribing Higher in Rural Versus Urban Areas

TUESDAY, Jan. 22, 2019 (HealthDay News) — The percentage of individuals prescribed an opioid is higher in rural than urban areas, according to research published in the Jan. 18 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Messages for Increasing Parental Confidence in HPV Vaccine ID’d

TUESDAY, Jan. 22, 2019 (HealthDay News) — Providing information on the benefits of vaccination, including cancer prevention, and avoiding expressing urgency to vaccinate can increase parent confidence in human papillomavirus (HPV) vaccination, according to a study published online Jan. 22 in Pediatrics.

Review Gives Guidance to Support Teens With Gender Dysphoria

TUESDAY, Jan. 22, 2019 (HealthDay News) — Primary care providers are well positioned to provide critical support and personalized care for youth with gender dysphoria and their caregivers or families, according to a review published online Jan. 21 in CMAJ, the journal of the Canadian Medical Association.

Repeat Tubal Procedures Up After Hysteroscopic Sterilization

TUESDAY, Jan. 22, 2019 (HealthDay News) — Hysteroscopic sterilization is associated with an increased risk for additional tubal intervention within seven years compared with laparoscopic sterilization, according to a study published online Jan. 8 in Obstetrics & Gynecology.

Mindfulness, Stress Linked to Menopausal Symptoms

FRIDAY, Jan. 18, 2019 (HealthDay News) — Higher mindfulness and lower stress are independently associated with lower menopausal symptom scores among midlife women, according to a study published online Jan. 17 in Climacteric.

Trained Alert Dogs Can Detect Impending T1DM-Related Events

FRIDAY, Jan. 18, 2019 (HealthDay News) — Trained alert dogs can help patients with type 1 diabetes regulate their blood glucose levels, according to a study published online Jan. 15 in PLOS ONE.

Mandated Neonatal Abstinence Reporting Helps Quantify Cases

FRIDAY, Jan. 18, 2019 (HealthDay News) — Mandated neonatal abstinence syndrome (NAS) surveillance and reporting allows state health departments to quantify incidence and informs programs and services, according to research published in the Jan. 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

FDA Down to 5 Weeks of Funding to Review New Drug Applications

THURSDAY, Jan. 17, 2019 (HealthDay News) — Due to the federal government shutdown, the U.S. Food and Drug Administration has only about five weeks of funding left to review new drug applications, according to Commissioner Scott Gottlieb, M.D.

CNN News Article

Achieving Healthy Diet From Sustainable Food Feasible

THURSDAY, Jan. 17, 2019 (HealthDay News) — Achieving a healthy diet from sustainable food systems is feasible but will require considerable shifts toward healthy dietary patterns, according to a report from the EAT-Lancet Commission published online Jan. 16 by The Lancet.

EAT-Lancet Commission (subscription or payment may be required)
Editorial (subscription or payment may be required)

Prevalence of Knee OA Lower With Menopausal Hormone Therapy

THURSDAY, Jan. 17, 2019 (HealthDay News) — For postmenopausal women, the prevalence of knee osteoarthritis is lower with menopausal hormone therapy (MHT) use, according to a study published online Dec. 21 in Menopause.

Breast Cancer Patients Do Not Overreact to Genetic Testing

THURSDAY, Jan. 17, 2019 (HealthDay News) — Among breast cancer patients, more extensive genetic testing is not associated with increased cancer worry, according to a study recently published in JCO Precision Oncology.

Low-Income Women Lack Menstrual Hygiene Supplies

WEDNESDAY, Jan. 16, 2019 (HealthDay News) — Many low-income women cannot afford menstrual hygiene supplies, according to a study published online Jan. 8 in Obstetrics & Gynecology.

Adoption of Advanced Health IT Capabilities Inconsistent

WEDNESDAY, Jan. 16, 2019 (HealthDay News) — Adoption of advanced health information technology (HIT) capabilities is inconsistent across health care systems, with electronic health record (EHR) standardization being the strongest predictor of advanced capabilities, according to a study published in the January issue of the American Journal of Managed Care.

Intermittent Fasts Plus Energy Restriction Best for Weight Loss

WEDNESDAY, Jan. 16, 2019 (HealthDay News) — Intermittent fasting with restricted energy intake may provide better outcomes than daily continuous diet restriction for health and weight loss in obese women, according to a study published in the January issue of Obesity.

Replacing Sitting Time With Activity Lowers Mortality Risk

WEDNESDAY, Jan. 16, 2019 (HealthDay News) — Replacing prolonged sedentary bouts with physical activity reduces mortality risk, but no benefit is seen for replacement with short sedentary bouts, according to a study recently published in the American Journal of Epidemiology.

Review Shares Best Practices for Evaluating Penicillin Allergy

WEDNESDAY, Jan. 16, 2019 (HealthDay News) — A new review, published in the Jan. 15 issue of the Journal of the American Medical Association, addresses best practices for the evaluation and management of reported penicillin allergies.

Components of Ideal Cardio Health Cut Diabetes Risk

WEDNESDAY, Jan. 16, 2019 (HealthDay News) — For individuals with normal fasting glucose but not those with impaired fasting glucose (IFG), a higher number of ideal cardiovascular health (CVH) components correlates with a lower risk for diabetes, according to a study published online Jan. 15 in Diabetologia.

USPSTF Recommends Risk-Reducing Meds for Breast Cancer

TUESDAY, Jan. 15, 2019 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends risk-reducing medications for women at high risk for breast cancer who are at low risk for adverse events, but medications are not recommended for routine use. These recommendations form the basis of a draft recommendation statement published online Jan. 15 by the task force.

Draft Recommendation Statement
Draft Evidence Review
Comment on Recommendation

American College of Physicians Releases 7th Edition of Ethics Manual

TUESDAY, Jan. 15, 2019 (HealthDay News) — Ethical principles are discussed in an updated Ethics Manual, issued by the American College of Physicians (ACP) and published as a supplement to the Jan. 15 issue of the Annals of Internal Medicine.

American College of Physicians Ethics Manual
Editorial (subscription or payment may be required)

Comorbidities Adversely Linked to Cancer Trial Participation

TUESDAY, Jan. 15, 2019 (HealthDay News) — For cancer patients, the presence of comorbidities is adversely linked to trial discussions, trial offers, and trial participation, according to a study published online Jan. 10 in JAMA Oncology.

Study Explores Influence of Genetics, Environment in Disease

TUESDAY, Jan. 15, 2019 (HealthDay News) — The influence of heritability and environmental factors has been identified for a large number of phenotypes, according to a study published online Jan. 14 in Nature Genetics.

Opioids Now More Deadly for Americans Than Traffic Accidents

TUESDAY, Jan. 15, 2019 (HealthDay News) — For the first time in history, Americans’ risk for dying from an opioid overdose is higher than their risk for dying in a car accident, the National Safety Council reported Monday.

Delayed Contraception Leads to Early Unwanted Pregnancy

TUESDAY, Jan. 15, 2019 (HealthDay News) — Delayed contraceptive initiation is associated with unwanted pregnancy within three months of sexual debut, according to a study published online Jan. 15 in Pediatrics.

Breast Cancer Incidence Up With Persistent Vasomotor Symptoms

MONDAY, Jan. 14, 2019 (HealthDay News) — Postmenopausal women with persistent vasomotor symptoms (VMS) have an increased incidence of breast cancer, according to a study published online Dec. 28 in Menopause.

Postpartum New-Onset Mental Illness Risk Up With IBD

MONDAY, Jan. 14, 2019 (HealthDay News) — Women with inflammatory bowel disease (IBD) have an increased risk for new-onset psychiatric diagnosis in the postpartum period, according to a study published online Jan. 10 in Gut.

Menopausal Hormone Tx Use Down Post-WHI Recommendations

MONDAY, Jan. 14, 2019 (HealthDay News) — The Women’s Health Initiative (WHI) recommendations for menopausal hormone therapy (MHT) use issued in 2002 have been widely adopted, according to a study published online Dec. 21 in Menopause.

CDC: Flu Cases Hit 7 Million in the United States

FRIDAY, Jan. 11, 2019 (HealthDay News) — The flu season is picking up steam, with about 7 million Americans having been struck by a strain of the flu virus, health officials said Friday.

Drug Overdose Death Rate Increasing Among Middle-Aged Women

FRIDAY, Jan. 11, 2019 (HealthDay News) — From 1999 to 2017, the drug overdose death rate increased 260 percent among women aged 30 to 64 years, according to research published in the Jan. 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

High Fiber Intake Tied to Lower Risk for Noncommunicable Disease

FRIDAY, Jan. 11, 2019 (HealthDay News) — High intake of fiber is associated with a reduced risk for several noncommunicable diseases (NCDs), according to research published online Jan. 10 in the The Lancet.

Use of Diabetes Monitoring Tests in Primary Care Suboptimal

FRIDAY, Jan. 11, 2019 (HealthDay News) — Many primary care patients are not given tests recommended for monitoring diabetes, according to a study published in the December issue of Family Medicine and Community Health.

Adverse Birth Outcomes Up for Women With H1N1 Flu in ICU

FRIDAY, Jan. 11, 2019 (HealthDay News) — Pregnant women with 2009 H1N1 influenza admitted to an intensive care unit (ICU) have an increased risk for adverse birth outcomes, according to a study published online Jan. 9 in Birth Defects Research.

Prices Still Explain High U.S. Health Care Spending

FRIDAY, Jan. 11, 2019 (HealthDay News) — The difference in health spending between the United States and other countries is still explained by health care prices, according to a study published in the January issue of Health Affairs.

Algorithm Evaluates Cervical Images to ID Precancer, Cancer

THURSDAY, Jan. 10, 2019 (HealthDay News) — A deep learning-based visual evaluation algorithm can detect cervical precancer/cancer with higher accuracy than conventional cytology, according to a study published online Jan. 10 in the Journal of the National Cancer Institute.

CDC: E. Coli Outbreak Linked to Romaine Lettuce Is Over

THURSDAY, Jan. 10, 2019 (HealthDay News) — The Escherichia coli outbreak linked to California-grown romaine lettuce appears to be over, the U.S. Centers for Disease Control and Prevention said Wednesday.

Doctors Question State Lawsuits Over Pelvic Mesh Products

THURSDAY, Jan. 10, 2019 (HealthDay News) — State lawsuits over pelvic mesh products could scare women away from the products or even get them removed from the market, a group of doctors say.

AP News Article

Total Fertility Rates Vary by State

THURSDAY, Jan. 10, 2019 (HealthDay News) — There is considerable state-level variation in total fertility rates for each race and Hispanic-origin group, according to a study published Jan. 10 in National Vital Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

Transdermal HRT Not Linked to Increased Risk for VTE

THURSDAY, Jan. 10, 2019 (HealthDay News) — Oral hormone replacement therapy (HRT) is associated with an increased risk for venous thromboembolism (VTE), while transdermal preparations are not linked to increased risk, according to a study published online Jan. 9 in the BMJ.

Private Equity Acquisition of Physician Practices Discussed

THURSDAY, Jan. 10, 2019 (HealthDay News) — The phenomenon of private equity acquisition of physician practices is discussed in an Ideas and Opinions piece published online Jan. 8 in the Annals of Internal Medicine.

Obesity Linked to Lower Gray Matter Brain Volume

WEDNESDAY, Jan. 9, 2019 (HealthDay News) — Obesity is associated with lower gray matter brain volumes, according to a study published online Jan. 9 in Neurology.

No Increased Fall Risk With HTN Treatment in Older Women

WEDNESDAY, Jan. 9, 2019 (HealthDay News) — Treating high blood pressure (BP) is not associated with an increased fall risk among older women, according to a study published online Jan. 7 in the Journal of the American Geriatrics Society.

Long Work Hours Tied to Poor Glycemic Control in T2DM

WEDNESDAY, Jan. 9, 2019 (HealthDay News) — Long work hours (≥60 hours/week) are associated with poor glycemic control in young Japanese men with type 2 diabetes, according to a study published in the January issue of the Journal of Diabetes Investigation.

Many Female Health Care Workers Live in Poverty

WEDNESDAY, Jan. 9, 2019 (HealthDay News) — Many U.S. female health care workers, particularly women of color, live in poverty and lack health insurance, according to a study published online Dec. 20 in the American Journal of Public Health.

Increase in Brand-Name Drug Cost Mainly Due to Existing Drugs

WEDNESDAY, Jan. 9, 2019 (HealthDay News) — The costs of oral and injectable brand-name drugs increased from 2008 to 2016, with most of the increase due to existing drugs, while new drugs accounted for cost increases in specialty and generic drugs, according to a study published in the January issue of Health Affairs.

Medical Marketing Has Increased in Past 20 Years

TUESDAY, Jan. 8, 2019 (HealthDay News) — From 1997 through 2016, there was an increase in medical marketing, especially direct-to-consumer (DTC) advertising, according to research published in the Jan. 1/8 issue of the Journal of the American Medical Association.

USPSTF Affirms Guidance for Hep B Screening at First Prenatal Visit

TUESDAY, Jan. 8, 2019 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends hepatitis B virus (HBV) infection screening in pregnant women at their first prenatal visit. These findings form the basis of a draft recommendation statement published online Jan. 8 by the task force.

Draft Recommendation Statement
Draft Evidence Review
Comment on Recommendation

Cervical Cancer Screening Rates ‘Unacceptably Low’

TUESDAY, Jan. 8, 2019 (HealthDay News) — Less than two-thirds of eligible 30- to 65-year-old women are up to date with cervical cancer screening, and Pap completion rates have decreased over time, according to a study published online Jan. 7 in the Journal of Women’s Health.

Women With CVD Have Worse Self-Reported Outcomes

TUESDAY, Jan. 8, 2019 (HealthDay News) — Compared with men, women with atherosclerotic cardiovascular disease (ASCVD) are more likely to report poorer patient experience, lower health-related quality of life, and poorer perception of their health, according to a study recently published online in the Journal of the American Heart Association.

Cancer Death Rate in U.S. Decreased Continuously From 1991 to 2016

TUESDAY, Jan. 8, 2019 (HealthDay News) — The overall cancer death rate decreased continuously by 27 percent from 1991 to 2016, according to a report published online Jan. 8 in CA: A Cancer Journal for Clinicians.

ACA Coverage Gains Could Erode Without Individual Mandate

TUESDAY, Jan. 8, 2019 (HealthDay News) — Eliminating the Affordable Care Act’s individual mandate penalty is unlikely to destabilize the individual market in California but could roll back coverage gains, according to a study published in the January issue of Health Affairs.

Screening Donated Blood for Zika Not Cost-Effective

MONDAY, Jan. 7, 2019 (HealthDay News) — Screening donated blood for Zika virus is cost-effective only in the high mosquito season in Puerto Rico, according to a study published online Jan. 8 in the Annals of Internal Medicine.

Gabapentin Improves Sexual Function in Provoked Vulvodynia

MONDAY, Jan. 7, 2019 (HealthDay News) — For women with provoked vulvodynia, gabapentin improves sexual function compared with placebo, although overall sexual function is still lower than for pain-free controls, according to a study published in the January issue of the American Journal of Obstetrics and Gynecology.

Childhood Hodgkin Lymphoma Survivors at Risk for Later Cancers

MONDAY, Jan. 7, 2019 (HealthDay News) — Survivors of childhood Hodgkin lymphoma (HL) remain at increased risk for developing subsequent malignant neoplasms (SMNs), according to research published online Dec. 17 in Cancer.

Prenatal Valproate Exposure Linked to Increased ADHD Risk

FRIDAY, Jan. 4, 2019 (HealthDay News) — Use of the antiepileptic drug (AED) valproate during pregnancy is associated with an increased risk for attention-deficit/hyperactivity disorder (ADHD) among offspring, according to a study published online Jan. 4 in JAMA Network Open.

Health Benefits of Nonsugar Sweeteners Uncertain

FRIDAY, Jan. 4, 2019 (HealthDay News) — There is no compelling evidence to indicate health benefits of nonsugar sweetener (NSS) use on a range of health outcomes, according to a review published online Jan. 2 in The BMJ.

Risk for MCI Up With Progressive Cerebral Small Vessel Disease

FRIDAY, Jan. 4, 2019 (HealthDay News) — Patients with hypertension with progression of periventricular white matter hyperintensities have an increased risk for incident mild cognitive impairment, according to a study published online Jan. 4 in Hypertension.

Psychoeducational Intervention of Little Benefit in Breast Cancer

FRIDAY, Jan. 4, 2019 (HealthDay News) — A psychoeducational intervention does not improve anxiety or body image but is still considered important among women with breast cancer, according to a study recently published in Reviews on Recent Clinical Trials.

Breast Cancer Disparities Mostly Explained by Facility Factors

THURSDAY, Jan. 3, 2019 (HealthDay News) — Delays in diagnosis and use of under-resourced health centers account for most racial and ethnic disparities in breast cancer diagnosis, according to a study published online Jan. 2 in Cancer Epidemiology, Biomarkers & Prevention.

Partner-Delivered HIV Self-Testing Can Up Linkage to Care

WEDNESDAY, Jan, 2, 2019 (HealthDay News) — Partner-delivered HIV self-testing (HIVST) with financial incentives or reminders can increase the odds of male partners being linked to care or prevention, according to a study published online Jan. 2 in PLOS Medicine.

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