Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for January 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Glecaprevir-Pibrentasvir Effective Treatment for HCV Genotypes 1, 3
WEDNESDAY, Jan. 31, 2018 (HealthDay News) — Once-daily treatment with glecaprevir-pibrentasvir appears safe and effective for the treatment of hepatitis C virus (HCV) genotype 1 or 3, according to a study published in the Jan. 25 issue of the New England Journal of Medicine.
Survival Trends for Cancer Generally Increasing Worldwide
WEDNESDAY, Jan. 31, 2018 (HealthDay News) — Worldwide, survival trends for cancer are generally increasing, although there is considerable global variation in survival rates, according to a study published online Jan. 30 in The Lancet.
Increased Risk of Appendicitis One Week After Colonoscopy
TUESDAY, Jan. 30, 2018 (HealthDay News) — The risk of appendicitis is increased in the week following colonoscopy, according to a research letter published in the January issue of JAMA Surgery.
Surgeon Case Experience Impacts Peds Cholecystectomy Morbidity
TUESDAY, Jan. 30, 2018 (HealthDay News) — High-volume general surgeons have lower morbidity rates than low-volume pediatric surgeons for laparoscopic cholecystectomy in pediatric patients, independent of pediatric volume, according to a study published online Jan. 17 in JAMA Surgery.
Regulators Trying to Reduce Physician Burden Linked to EHR
MONDAY, Jan. 29, 2018 (HealthDay News) — The Office of the National Coordinator for Health Information Technology (ONC) is trying to address some of the issues relating to physician electronic health record (EHR) burden, partly with the appointment of Don Rucker, M.D., who is skilled in informatics and board-certified in emergency and internal medicine, according to an article published in Medical Economics.
Pre-Op Physical Therapy May Cut Pulmonary Complications
MONDAY, Jan. 29, 2018 (HealthDay News) — A 30-minute preoperative physical therapy session focused on breathing exercises is associated with a reduced incidence of postoperative pulmonary complications (PPCs) among patients undergoing upper abdominal surgery, according to a study published online Jan. 24 in The BMJ.
Health Care Spending Up, Mainly Due to Rising Prices
MONDAY, Jan. 29, 2018 (HealthDay News) — Americans under age 65 years who were insured through their employer spent more than ever before on health care in 2016, with faster spending growth in 2016 than in recent years, according to the Health Care Cost Institute (HCCI)’s annual Health Care Cost and Utilization Report.
FDA Approves Lutathera for Some Gastro and Pancreatic Cancers
FRIDAY, Jan. 26, 2018 (HealthDay News) — Lutathera (lutetium Lu 177 dotatate) is the first radioactive drug to be approved by the U.S. Food and Drug Administration to treat somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs), the agency said Friday in a news release.
Odds of Post-Op Mortality Increase As Weekend Approaches
FRIDAY, Jan. 26, 2018 (HealthDay News) — Following elective surgery, the odds of mortality rise in a graded manner as the day of the week of surgery approaches the weekend, according to research published in the February issue of Medical Care.
Care for Key Surgical Issues Up With ACA Medicaid Expansion
THURSDAY, Jan. 25, 2018 (HealthDay News) — For patients with five common surgical conditions, the Affordable Care Act (ACA)’s Medicaid expansion was associated with increased probability of early presentation and of receiving optimal management, according to a study published online Jan. 24 in JAMA Surgery.
Hyperandrogenism May Affect Gut Microbiome in PCOS
WEDNESDAY, Jan. 24, 2018 (HealthDay News) — Hyperandrogenism may play a role in changing the gut microbiome in women with polycystic ovary syndrome (PCOS), according to a study published online Jan. 23 in the Journal of Clinical Endocrinology & Metabolism.
Probiotics Tied to Lower Preterm Delivery, Preeclampsia Risk
WEDNESDAY, Jan. 24, 2018 (HealthDay News) — Probiotic milk consumption during pregnancy may be tied to a reduced incidence of preeclampsia and preterm delivery, according to a study published online Jan. 23 in BMJ Open.
Periodontitis in Older Adults Tied to Higher Total Cancer Risk
TUESDAY, Jan. 23, 2018 (HealthDay News) — Individuals with periodontitis have an increased total cancer risk, according to a study published online Jan. 12 in the Journal of the National Cancer Institute.
Drinking in Early Adulthood Tied to Later Risk for Liver Disease
TUESDAY, Jan. 23, 2018 (HealthDay News) — Alcohol consumption in young men is associated with an increased risk of severe liver disease later in life, according to a study published online Jan. 22 in the Journal of Hepatology.
Out-of-Pocket Expenditures Down With ACA Implementation
TUESDAY, Jan. 23, 2018 (HealthDay News) — Implementation of the Affordable Care Act (ACA) was associated with reduced out-of-pocket spending, although increases were noted in mean premium spending, according to a study published online Jan. 22 in JAMA Internal Medicine.
Swallowable Device Can Test for DNA Markers of Barrett’s
TUESDAY, Jan. 23, 2018 (HealthDay News) — A swallowable balloon device has been developed to obtain samples from the lower esophagus — samples which then undergo assay of combined CCNA1 and VIM DNA methylation to detect Barrett’s esophagus metaplasia, according to a study published online Jan. 17 in Science Translational Medicine.
Blood Test Found to Detect Eight Common Cancer Types
FRIDAY, Jan. 19, 2018 (HealthDay News) — A multi-analyte blood test, CancerSEEK, can detect eight common cancer types, with high sensitivity and specificity, according to a study published online Jan. 18 in Science.
Alcohol Induced DNA Repair Genes Prognostic in Gastric Cancer
THURSDAY, Jan. 18, 2018 (HealthDay News) — For patients with gastric cancer (GC), myeloperoxidase (MPO), transcription factor IIB-related factor 1 (BRF1), and breast cancer susceptibility genes 1 and 2 (BRCA1/2) induced by alcohol have prognostic value, according to a study published in the February issue of The American Journal of Pathology.
Proinflammatory Diet Linked to Increased Colorectal Cancer Risk
THURSDAY, Jan. 18, 2018 (HealthDay News) — Proinflammatory diets are associated with increased colorectal cancer risk for men and women, according to a study published online Jan. 18 in JAMA Oncology.
Increased Risk of Complications With Bariatric Surgery
THURSDAY, Jan. 18, 2018 (HealthDay News) — Bariatric surgery is associated with lower risks of obesity-related comorbidities but a clinically important increased risk for complications compared with medical treatment, according to a study published in the Jan. 16 issue of the Journal of the American Medical Association, a theme issue on obesity.
Professionals Disagree About Asking Patients About Sexuality
THURSDAY, Jan. 18, 2018 (HealthDay News) — National Health Service (NHS) England recently recommended that professionals ask all patients their sexual orientation at every opportunity, although opinions are divided on whether this is appropriate, according to an article published online Jan. 17 in The BMJ.
Significant Ultrasound Practice Needed to Diagnose Appendicitis
THURSDAY, Jan. 18, 2018 (HealthDay News) — There is a learning curve among novice emergency medicine residents in using emergency ultrasonography to diagnose acute appendicitis, according to a study published online Jan. 5 in the Journal of Clinical Ultrasound.
Lap Sleeve Gastrectomy, RYGB Equally Effective in Weight Loss
WEDNESDAY, Jan. 17, 2018 (HealthDay News) — For patients with morbid obesity, there is no statistically significant difference in terms of weight loss at five years after laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass, according to two studies published in the Jan. 16 issue of the Journal of the American Medical Association, a theme issue on obesity.
Abstract/Full Text – Peterli (subscription or payment may be required)
Abstract/Full Text – Salminen (subscription or payment may be required)
Editorial (subscription or payment may be required)
Psoriasis Remission Described After Hepatitis C Virus Treatment
WEDNESDAY, Jan. 17, 2018 (HealthDay News) — A case of remission of psoriasis after treatment of chronic hepatitis C virus (HCV) has been described in a research letter published online Jan. 16 in the Annals of Internal Medicine.
Reduced All-Cause Mortality for Obese Patients After Bariatric Sx
TUESDAY, Jan. 16, 2018 (HealthDay News) — Obese patients who undergo bariatric surgery have reduced all-cause mortality; and obese adults with type 2 diabetes who undergo gastric bypass have improved outcomes compared with lifestyle and intensive medical management alone, according to two studies published in the Jan. 16 issue of the Journal of the American Medical Association, a theme issue on obesity.
Abstract/Full Text – Reges (subscription or payment may be required)
Abstract/Full Text – Ikramuddin (subscription or payment may be required)
Editorial (subscription or payment may be required)
Ceramide-Infused Skin Barrier Cuts Stoma-Related Costs
FRIDAY, Jan. 12, 2018 (HealthDay News) — Use of a ceramide-infused ostomy skin barrier is associated with reduced stoma-related cost of care, according to a study published in the January/February issue of the Journal of Wound, Ostomy and Continence Nursing.
AMA Online Tools Address Systems-Level Physician Burnout
THURSDAY, Jan. 11, 2018 (HealthDay News) — Tools and resources have been developed to help address physician burnout at the systems level, which may affect more than half of doctors, according to a report published by the American Medical Association (AMA).
Prenatal PPI, H2 Blocker Use Linked to Asthma Risk in Child
THURSDAY, Jan. 11, 2018 (HealthDay News) — Prenatal, maternal, acid-suppressive drug use is associated with an increased risk of childhood asthma, according to a review published online Jan. 11 in Pediatrics.
Hepatic Fat Accumulation May Have Causal Role in Liver Disease
THURSDAY, Jan. 11, 2018 (HealthDay News) — Hepatic fat accumulation may play a causal role in chronic liver disease, according to a study published online Dec. 27 in the Journal of Internal Medicine.
Psoriasis Is Independent Risk Factor for Comorbidity in Children
THURSDAY, Jan. 11, 2018 (HealthDay News) — Children with psoriasis have an increased risk of comorbidities compared to children without psoriasis, independent of obesity, according to a study published online Jan. 10 in JAMA Dermatology.
Economic Impact of Physicians Quantified for 2015
WEDNESDAY, Jan. 10, 2018 (HealthDay News) — Physicians have a large economic impact across the nation, creating an aggregate of $2.3 trillion of economic activity and supporting employment of nearly 12.6 million Americans, according to a report published by the American Medical Association.
Long-Term Night Shift Work Linked to Cancer Risk in Women
TUESDAY, Jan. 9, 2018 (HealthDay News) — There is a positive association between long-term night shift work and the risk of several common cancers for women, with evidence of a dose-response correlation, according to a study published online Jan. 8 in Cancer Epidemiology, Biomarkers & Prevention.
Kidney Injury Common After Non-Kidney Transplants in Children
MONDAY, Jan. 8, 2018 (HealthDay News) — In children who receive a non-kidney solid organ transplant, acute kidney injury (AKI) is common in the first year after surgery and is associated with an increased risk of chronic kidney disease (CKD), according to a study published online Dec. 29 in the American Journal of Transplantation.
Abdominal Obstetric Binder Helpful for Cecal Intubation
MONDAY, Jan. 8, 2018 (HealthDay News) — Use of an abdominal obstetric binder (AOB) is associated with a faster and more effective colonoscope insertion during outpatient colonoscopy, according to a study published online Jan. 2 in the Journal of Gastroenterology and Hepatology.
Pharmacies Can Up Access to Direct-Acting Antivirals for Hep C
MONDAY, Jan. 8, 2018 (HealthDay News) — Provider collaboration with local specialty pharmacies (LSPs) is associated with reduced delays in therapy and lower rates of direct-acting antiviral (DAA) denial for patients with hepatitis C, according to a study published in the January/February issue of the Journal of the American Pharmacists Association.
Physicians Frequently Continue to Work While Ill
FRIDAY, Jan. 5, 2018 (HealthDay News) — Many physicians continue working and caring for patients while they are sick, according to an article published in Medical Economics.
Cancer Death Rate Continuing to Decline in United States
FRIDAY, Jan. 5, 2018 (HealthDay News) — In both men and women in the United States, the cancer death rate declined by about 1.5 percent annually from 2006 to 2015, according to a study published online Jan. 4 in CA: A Cancer Journal for Clinicians.
For Hospitals, No Benefit for Early Adoption of Financial Incentives
FRIDAY, Jan. 5, 2018 (HealthDay News) — Hospitals that volunteered to be under financial incentives for more than a decade as part of the Premier Hospital Quality Incentive Demonstration (early adopters) do not have better process scores or lower mortality than hospitals where these incentives were implemented later under the Hospital Value-Based Purchasing program (late adopters), according to a study published online Jan. 4 in The BMJ.
Half of Gastric Cancer Patients Diagnosed From ER Visit
THURSDAY, Jan. 4, 2018 (HealthDay News) — Half of patients with gastric cancer (GC) are diagnosed as a result of an emergency department visit, which is independently associated with increased mortality, according to a study published recently in the American Journal of Surgery.
Certain Stresses, Burnout Causing Some Women to Leave Medicine
THURSDAY, Jan. 4, 2018 (HealthDay News) — Though equal numbers of men and women are now entering medical schools, the majority of physicians are still male, and female physicians face several unique stressors, according to a report published online in Medical Economics.
Low Rates of Major Complications After Bariatric Surgery
THURSDAY, Jan. 4, 2018 (HealthDay News) — The rates of three major complications at less than 30 days after bariatric surgery are low and vary among surgical procedures, according to research published online Dec. 20 in Obesity Reviews.
Predictors of Infliximab Response in Ulcerative Colitis Identified
WEDNESDAY, Jan. 3, 2018 (HealthDay News) — For patients with acute severe ulcerative colitis (ASUC), the baseline Mayo Endoscopic Score and the C-reactive protein (CRP)/albumin ratio predict treatment response to infliximab, according to research published online Dec. 21 in the Journal of Gastroenterology and Hepatology.
Higher Risk of Musculoskeletal Disorders in Some Physicians
WEDNESDAY, Jan. 3, 2018 (HealthDay News) — The prevalence of work-related musculoskeletal disorders (MSDs) appears to be high for at-risk physicians, according to a review published online Dec. 27 in JAMA Surgery.
Same-Day, Low-Dose Bowel Prep Feasible for Colonoscopy
TUESDAY, Jan. 2, 2018 (HealthDay News) — A same-day, low-dose, 1-liter polyethylene glycol-based (1L-PEG) bowel preparation can achieve similar bowel cleansing to split-dose 4L-PEG bowel preparation in select high-risk patients before colonoscopy, according to a study published online Dec. 21 in the Journal of Digestive Diseases.
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