Here are what the editors at HealthDay consider to be the most important developments in Pathology for January 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
FDA Warns of Lead Poisoning Risk From Cosmetic Clay
FRIDAY, Jan. 29, 2016 (HealthDay News) — A beauty clay sold at major retail outlets may put users at risk for lead poisoning, the U.S. Food and Drug Administration warned Friday.
High Level of Tenofovir Resistance for Those With HIV
FRIDAY, Jan. 29, 2016 (HealthDay News) — HIV resistance to the antiretroviral drug tenofovir (Viread) is common, according to a study published online Jan. 28 in The Lancet Infectious Diseases.
Soy Foods May Blunt Reproductive Harm From BPA
FRIDAY, Jan. 29, 2016 (HealthDay News) — Soy intake may modify the association between bisphenol A (BPA) and fertility in women undergoing assisted reproduction, according to research published online Jan. 27 in the Journal of Clinical Endocrinology & Metabolism.
Severe Reaction to Pneumococcal Vaccines in Patients With CAPS
FRIDAY, Jan. 29, 2016 (HealthDay News) — Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the February issue of Arthritis & Rheumatology.
Pre-Op MRI Improves Accuracy for Predicting Extent of DCIS
FRIDAY, Jan. 29, 2016 (HealthDay News) — Preoperative magnetic resonance imaging (MRI) can add to mammography in predicting the extent of ductal carcinoma in situ (DCIS), according to a study published online Jan. 25 in the Journal of Medical Imaging and Radiation Oncology.
Earlier Age at Menarche Linked to Increased Risk of GDM
FRIDAY, Jan. 29, 2016 (HealthDay News) — Earlier age at menarche is associated with increased risk of gestational diabetes mellitus (GDM), according to a study published online Jan. 26 in Diabetes Care.
AMA Highlights Top Four Issues to Promote in State Legislation
THURSDAY, Jan. 28, 2016 (HealthDay News) — The top four issues that will be promoted in state legislation in 2016 were discussed at the 2016 American Medical Association (AMA) State Legislative Strategy Conference, according to a report published by the AMA.
HIV Can Replicate in Lymphoid Tissue Despite ART Success
THURSDAY, Jan. 28, 2016 (HealthDay News) — Even when blood tests of HIV patients on antiretroviral drugs show no sign of the virus, it can still be replicating in lymphoid tissue, according to research published online Jan. 27 in Nature.
New Approach Described for Type 1 Diabetes
THURSDAY, Jan. 28, 2016 (HealthDay News) — Alginate derivatives have been generated that can overcome the challenge of foreign body response in the use of implanted medical devices, and these materials show promise in diabetes, according to two studies published online Jan. 25 in Nature Biotechnology and Nature Medicine.
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Rosacea Linked to Increased Risk of Glioma
THURSDAY, Jan. 28, 2016 (HealthDay News) — Rosacea is associated with a significantly increased risk of developing glioma, according to research published online Jan. 27 in JAMA Dermatology.
Tysabri Impacts Seroconversion in John Cunningham Virus
THURSDAY, Jan. 28, 2016 (HealthDay News) — For patients with John Cunningham virus (JCV), natalizumab (Tysabri) treatment affects seroconversion and JCV index values, according to a study published online Jan. 27 in Neurology: Neuroimmunology & Neuroinflammation.
Clipping Nodes Improves Pathologic Evaluation
THURSDAY, Jan. 28, 2016 (HealthDay News) — Clipping nodes with biopsy-confirmed metastatic disease improves pathologic evaluation among patients with breast cancer, according to a study published online Jan. 25 in the Journal of Clinical Oncology.
~1% of Physicians Account for One-Third of Malpractice Claims
WEDNESDAY, Jan. 27, 2016 (HealthDay News) — A small number of physicians account for a considerable proportion of all paid malpractice claims, according to a study published in the Jan. 28 issue of the New England Journal of Medicine.
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Guidance Issued for Infants With Suspected Zika Infection
WEDNESDAY, Jan. 27, 2016 (HealthDay News) — Interim guidelines have been developed for the evaluation and testing of infants born to mothers who traveled to or resided in an area with Zika virus transmission during pregnancy. The guidelines were published in the Jan. 26 early-release issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.
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Specific Trichoscopic Findings Linked to Tinea Capitis
WEDNESDAY, Jan. 27, 2016 (HealthDay News) — Specific trichoscopic findings are associated with tinea capitis (TC), according to a research letter published online Jan. 22 in the British Journal of Dermatology.
Too Few Nurses Compliant With Standard Precautions
WEDNESDAY, Jan. 27, 2016 (HealthDay News) — Fewer than 20 percent of nurses report compliance with all nine Standard Precautions (SP), although adherence is the most effective means of preventing bloodborne pathogen transmission, according to a study published in the Jan. 1 issue of the American Journal of Infection Control.
Clinical Significance of Varying Degrees of Neutropenia Explored
WEDNESDAY, Jan. 27, 2016 (HealthDay News) — Neutropenia is associated with viral infections and hematological malignancies in a dose-dependent manner, according to a study published online Jan. 21 in the Journal of Internal Medicine.
Extended Elevated Recurrence Rates for ER-Positive Breast CA
WEDNESDAY, Jan. 27, 2016 (HealthDay News) — Breast cancer patients with estrogen receptor (ER)-positive disease have elevated annualized hazards of recurrence during extended follow-up, according to a study published online Jan. 18 in the Journal of Clinical Oncology.
Possibility for Health Care Legislation Changes in 2016
TUESDAY, Jan. 26, 2016 (HealthDay News) — Given the current political climate and issues of bipartisan concern, 2016 could see certain changes to health care legislation, according to a report published in Medical Economics.
Consistent CRC Detection Seen for Fecal Immunochemical Tests
TUESDAY, Jan. 26, 2016 (HealthDay News) — Fecal immunochemical tests (FITs) can consistently detect colorectal cancer when used on an annual basis, and they are effective even in the second, third, and fourth years of screening, according to a study published online Jan. 26 in the Annals of Internal Medicine.
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Prednisolone Therapy Induces Procoagulant State
TUESDAY, Jan. 26, 2016 (HealthDay News) — For healthy subjects, 10 days of prednisolone therapy induces a procoagulant state, according to a study published online Jan. 21 in the Journal of Thrombosis and Haemostasis.
ACP Presents High-Value Care Advice for Hematuria
TUESDAY, Jan. 26, 2016 (HealthDay News) — In a clinical guideline published online Jan. 26 in the Annals of Internal Medicine, recommendations relating to evaluation of hematuria are presented for clinicians.
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About 1 in 7 Colorectal Cancer Patients Younger Than 50
MONDAY, Jan. 25, 2016 (HealthDay News) — Nearly one in seven colorectal cancer patients are under 50, and younger patients are more likely to have advanced-stage cancer, according to a report published online Jan. 25 in Cancer.
Hypoglycemia, Atherosclerosis Progression Link Explored
MONDAY, Jan. 25, 2016 (HealthDay News) — In the Veterans Affairs Diabetes Trial, hypoglycemia was associated with coronary artery calcium (CAC) progression only in the standard therapy group (versus intensive therapy), according to research published online Jan. 19 in Diabetes Care.
Estrogen Metabolism May Have an Impact on Stroke Recovery
MONDAY, Jan. 25, 2016 (HealthDay News) — 2-methoxyestradiol (2-ME), an endogenous metabolite of estradiol, inhibits proliferation, pro-inflammatory responses, and phagocytosis in microglia, according to a study published online Jan. 5 in the American Journal of Physiology-Endocrinology and Metabolism.
Research Suggests Broader Role for HPV in HNSCC Etiology
MONDAY, Jan. 25, 2016 (HealthDay News) — Human papillomavirus (HPV)-16 detection is tied to incidence of oropharyngeal squamous cell carcinoma (SCC); and other HPVs, including γ11- and γ12-HPV species and β1-HPV-5 type, are also associated with head and neck squamous cell carcinoma (HNSCC), according to a study published online Jan. 21 in JAMA Oncology.
Only Severe Preeclampsia Linked to Antiβ2GP1 Immunoglobulin G
MONDAY, Jan. 25, 2016 (HealthDay News) — Severe preeclampsia (S-PEecl), but not non-severe preeclampsia (NS-PEecl), is associated with antiβ2GP1 immunoglobulin (Ig)G, according to a study published online Jan. 18 in the Journal of Thrombosis and Haemostasis.
ACOG Supports CDC’s Zika Virus Travel Precautions
FRIDAY, Jan. 22, 2016 (HealthDay News) — The American College of Obstetricians and Gynecologists (ACOG) has issued a statement and practice advisory in support of new guidelines aimed at shielding pregnant women from the mosquito-borne Zika virus.
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CDC: Increasing Rate of Gastroschisis Seen in U.S.
FRIDAY, Jan. 22, 2016 (HealthDay News) — The birth defect gastroschisis among U.S. infants has increased over the past 18 years, according to research published in the Jan. 22 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.
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Many Seniors Getting Unneeded Mammography, PSA Screens
FRIDAY, Jan. 22, 2016 (HealthDay News) — Many older Americans are unnecessarily screened for breast and prostate cancer, according to a research letter published online Jan. 21 in JAMA Oncology.
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Pediatric Nasopharyngeal CA Has Different Patient Demographic
FRIDAY, Jan. 22, 2016 (HealthDay News) — Pediatric patients with nasopharyngeal carcinoma (NPC) are more often black and present with stage IV disease, but they have lower mortality than adult patients, according to a study published online Jan. 14 in JAMA Otolaryngology-Head & Neck Surgery.
Curcumin Cuts Acetaminophen-Induced Hepatotoxicity in Mice
FRIDAY, Jan. 22, 2016 (HealthDay News) — Curcumin can attenuate acetaminophen-induced mitochondrial alterations in the livers of mice, according to an experimental study published online Jan. 15 in the Journal of Pharmacy and Pharmacology.
Inhibition of mTOR Restores Corticosteroid Sensitivity in COPD
FRIDAY, Jan. 22, 2016 (HealthDay News) — Inhibition of mammalian target of rapamycin (mTOR) by rapamycin restores corticosteroid sensitivity in patients with chronic obstructive pulmonary disease (COPD), according to a study published in the Jan. 15 issue of the American Journal of Respiratory and Critical Care Medicine.
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Blood Test May Help Predict Acute Myeloid Leukemia Return
THURSDAY, Jan. 21, 2016 (HealthDay News) — A simple blood test may be an inexpensive, easy, and effective way to predict risk of recurrence of a common form of acute myeloid leukemia (AML), characterized by a mutation in the NPM1 gene, according to research published in the Jan. 21 issue of the New England Journal of Medicine.
Blood Test May Help Guide Appropriateness of Antibiotic Rx
THURSDAY, Jan. 21, 2016 (HealthDay News) — Researchers say they’re closer to developing a blood test that distinguishes between viral and bacterial respiratory infections. The findings are published in the Jan. 20 issue of Science Translational Medicine.
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Opt-Out Testing in the ER May Boost HIV Testing Rates
THURSDAY, Jan. 21, 2016 (HealthDay News) — “Opt-out” testing could significantly increase the number of patients who agree to be tested for HIV, according to research published online Jan. 19 in The BMJ.
Pregnancy Ups Metastasis, Recurrence, Death in Melanoma
THURSDAY, Jan. 21, 2016 (HealthDay News) — Women diagnosed with melanoma during or just after pregnancy are at greater risk from the cancer than other women, according to a study published online Jan. 20 in the Journal of the American Academy of Dermatology.
CDX2-Negative Colon Cancer May Need More Tx Post Surgery
THURSDAY, Jan. 21, 2016 (HealthDay News) — Colon tumors that don’t produce the protein CDX2 are more likely to recur following surgical removal in patients with stage II colon cancer, according to study findings published in the Jan. 21 issue of the New England Journal of Medicine.
Mutations in TUBB8 Linked to Form of Female Infertility
THURSDAY, Jan. 21, 2016 (HealthDay News) — For a small number of women with a rare form of infertility, mutations in a particular gene may be the cause, according to a study published in the Jan. 21 issue of the New England Journal of Medicine.
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Depressive Symptoms Linked to Coronary Artery Calcium
THURSDAY, Jan. 21, 2016 (HealthDay News) — Depressive symptoms seem to be associated with coronary artery calcium (CAC) in older men and women, according to a study published in the Feb. 1 issue of The American Journal of Cardiology.
Anesthesia After 40 Not Linked to Mild Cognitive Impairment
WEDNESDAY, Jan. 20, 2016 (HealthDay News) — Receiving general anesthesia for surgery after age 40 doesn’t appear to raise the risk for mild cognitive impairment later in life, according to a study published online Jan. 20 in the Mayo Clinic Proceedings.
Antipsychotic-Exposed Youths Have Increased T2DM Risk
WEDNESDAY, Jan. 20, 2016 (HealthDay News) — Youths treated with antipsychotics have increased cumulative risk and exposure-adjusted incidence of type 2 diabetes mellitus (T2DM), according to research published online Jan. 20 in JAMA Psychiatry.
Fluorescence Visualization-Guided Sx Efficacious in Oral CA
WEDNESDAY, Jan. 20, 2016 (HealthDay News) — For patients with oral cancer, fluorescence visualization (FV)-guided surgery is associated with a reduction in local recurrence, according to a study published online Jan. 14 in JAMA Otolaryngology-Head & Neck Surgery.
Physicians Choose Less Aggressive Care at End of Life
TUESDAY, Jan. 19, 2016 (HealthDay News) — Physicians facing death are less likely to demand aggressive care, according to two research letters published in the Jan. 19 issue of the Journal of the American Medical Association, a theme issue on death, dying, and end of life.
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CDC: HIV Testing Rates Still Low Among Teens, Young Adults
TUESDAY, Jan. 19, 2016 (HealthDay News) — An estimated 50 percent of young Americans infected with HIV don’t know they have it, according to research published online Jan. 19 in Pediatrics.
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CDC: Distribution of Lyme Disease Vectors Has Expanded
TUESDAY, Jan. 19, 2016 (HealthDay News) — Ticks that transmit Lyme disease are now found in nearly half of all counties in the United States, a much broader swath than was seen in the late 1990s, according to research published online Jan. 18 in the Journal of Medical Entomology.
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KRAS, BRAF V600E Mutations Impact Survival in Colon Cancer
MONDAY, Jan. 18, 2016 (HealthDay News) — For patients with stage III colon cancer treated with leucovorin, fluorouracil, and oxaliplatin (FOLFOX), KRAS and BRAF V600E mutations are associated with worse clinical outcome in patients with microsatellite-stable tumors, according to a study published online Jan. 14 in JAMA Oncology.
Earlier AMD Onset With Rare Genetic Variants
MONDAY, Jan. 18, 2016 (HealthDay News) — Patients with age-related macular degeneration (AMD) carrying rare variants have earlier age at symptom onset and a higher prevalence of positive family history than noncarriers, according to a study published online Jan. 14 in JAMA Ophthalmology.
Greater Transparency Being Promoted in Research
MONDAY, Jan. 18, 2016 (HealthDay News) — Greater transparency is being promoted in clinical research, according to a health policy brief published online Jan. 14 in Health Affairs.
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FDA Approves Newly Designed Olympus Endoscope
MONDAY, Jan. 18, 2016 (HealthDay News) — A newly designed Olympus duodenoscope was approved Friday by the U.S. Food and Drug Administration.
Guidelines Presented for Primary Adrenal Insufficiency
MONDAY, Jan. 18, 2016 (HealthDay News) — Recommendations have been developed to address the diagnosis and treatment of primary adrenal insufficiency. The new clinical practical guidelines were published online Jan. 13 in the Journal of Clinical Endocrinology & Metabolism.
Foreign-Born Students in U.S. Have Higher Case Rate of TB
MONDAY, Jan. 18, 2016 (HealthDay News) — Foreign-born students in the United States have a higher case rate of tuberculosis (TB) than other foreign-born individuals, according to a study published online Jan. 5 in the Annals of the American Thoracic Society.
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Pertussis Outbreak Described in Preschool in Tallahassee
MONDAY, Jan. 18, 2016 (HealthDay News) — A report published online Jan. 13 in the U.S. Centers for Disease Control and Prevention’s Emerging Infectious Diseases highlights a 2013 pertussis outbreak among mainly vaccinated preschool-aged children.
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Mortality Up With Low Bicarb Levels in Healthy Seniors
FRIDAY, Jan. 15, 2016 (HealthDay News) — Seniors who are healthy but have low blood levels of bicarbonate are at higher risk for premature death, according to a study published online Jan. 14 in the Clinical Journal of the American Society of Nephrology.
Nitrate Intake Linked to Primary Open-Angle Glaucoma Risk
FRIDAY, Jan. 15, 2016 (HealthDay News) — Higher dietary nitrate and green leafy vegetable intake is associated with reduced risk of primary open-angle glaucoma (POAG), according to a study published online Jan. 14 in JAMA Ophthalmology.
Prophylactic Antibiotic Choice Impacts Post-Hysterectomy SSI
FRIDAY, Jan. 15, 2016 (HealthDay News) — For women undergoing hysterectomy, prophylactic antibiotic choice impacts the risk of surgical site infection rates, according to a study published in the February issue of Obstetrics & Gynecology.
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Geographic Variation in HPV Oropharyngeal Cancer Prevalence
FRIDAY, Jan. 15, 2016 (HealthDay News) — There is geographic variation in the proportion of head and neck cancers attributable to human papillomavirus (HPV), according to a study published online Jan. 8 in Head & Neck.
Diabetes Mellitus Is Independent Risk Factor for A-Fib
FRIDAY, Jan. 15, 2016 (HealthDay News) — Within a general population from China, diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF), with the correlation persisting after adjustment for cardiovascular risk factors, according to a study published online Jan. 8 in the Journal of Diabetes Investigation.
WHO: West Africa Ebola Outbreak Is Over
THURSDAY, Jan. 14, 2016 (HealthDay News) — The two-year Ebola outbreak in West Africa that claimed more than 11,300 lives is over, the World Health Organization said Thursday.
Scope-Related Infections Higher Than Previously Thought
THURSDAY, Jan. 14, 2016 (HealthDay News) — More patients than previously estimated contracted life-threatening infections from contaminated medical scopes in recent years, according to a U.S. Senate committee report released Wednesday.
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Zika Virus Concerns May Curb Travel for Pregnant Women
THURSDAY, Jan. 14, 2016 (HealthDay News) — Pregnant women in the United States may be warned against traveling to Latin American and Caribbean countries where mosquitoes are spreading a virus that may cause brain damage in newborns.
Lower Risk of Parkinson’s With Higher Urate Concentration
THURSDAY, Jan. 14, 2016 (HealthDay News) — For men, but not women, the risk of developing Parkinson’s disease (PD) is lower with higher plasma urate concentrations, according to a study published online Jan. 13 in Neurology.
Geographic Factors Impact HPV Vaccine Initiation in Teen Girls
THURSDAY, Jan. 14, 2016 (HealthDay News) — Initiation of human papillomavirus (HPV) vaccination is highest among teen girls in poorer communities and in populations that are mainly Hispanic or mixed race, according to a study published online Jan. 14 in Cancer, Epidemiology, Biomarkers & Prevention.
Tickborne Bacteria Identified in Ticks from Texas
THURSDAY, Jan. 14, 2016 (HealthDay News) — About 23 percent of ticks from Texas carry bacterial DNA from at least one of the following: Rickettsia, Borrelia, and Ehrlichia spp., according to a report published online Jan. 13 in the U.S. Centers for Disease Control and Prevention’s Emerging Infectious Diseases.
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New Blood Test May Improve Tracking of Advanced Melanoma
WEDNESDAY, Jan. 13, 2016 (HealthDay News) — A new blood test might improve doctors’ ability to track the spread of advanced melanoma, according to results of a small, preliminary study published in the January issue of Molecular Oncology.
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Incidence of Radiation-Induced Breast Cancer Examined
WEDNESDAY, Jan. 13, 2016 (HealthDay News) — There is variability in radiation-induced breast cancer incidence and mortality associated with digital mammography screening, according to a study published online Jan. 12 in the Annals of Internal Medicine.
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Stem Cell Sources Used for HSCT Vary by Country, Resources
WEDNESDAY, Jan. 13, 2016 (HealthDay News) — Use of bone marrow as the stem cell source for hematopoietic stem cell transplantation (HSCT) increases with increasing incomes, according to a research letter published in the Jan. 12 issue of the Journal of the American Medical Association.
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PPARγ Antagonist Imatinib Improves Insulin Sensitivity
WEDNESDAY, Jan. 13, 2016 (HealthDay News) — Imatinib (Gleevec) blocks CDK5-mediated peroxisome proliferator-activated receptor γ (PPARγ) phosphorylation as an antagonist ligand, improving insulin sensitivity and promoting browning of white adipose tissue, according to a study published online Jan. 6 in Diabetes.
Allergic Rhinitis Constitutes Considerable Burden
WEDNESDAY, Jan. 13, 2016 (HealthDay News) — Allergic rhinitis (AR) constitutes a considerable burden, with patients at increased risk for asthma and various mental health comorbidities, according to a study published online Jan. 8 in Allergy.
Acute Ozone Exposure Ups Stress Hormone in Humans
WEDNESDAY, Jan. 13, 2016 (HealthDay News) — Acute ozone exposure increases stress hormones and causes alterations in peripheral lipid metabolism in humans, according to research published online Jan. 8 in the American Journal of Respiratory and Critical Care Medicine.
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Frozen Samples Comparable to Fresh in Fecal Transplant
TUESDAY, Jan. 12, 2016 (HealthDay News) — Frozen stool samples work just as well as freshly donated samples when treating Clostridium difficile infection through fecal transplantation, according to findings published in the Jan. 12 issue of the Journal of the American Medical Association.
Nivolumab, Contact Immunotx Treats In-Transit Melanoma
TUESDAY, Jan. 12, 2016 (HealthDay News) — Nivolumab in combination with contact immunotherapy can successfully treat in-transit melanoma, according to two case reports published online Dec. 12 in the Journal of Dermatology.
False-Positive Mammography Results Are Common
TUESDAY, Jan. 12, 2016 (HealthDay News) — For women undergoing digital mammography screening, false-positive results are common, especially among younger women and those with risk factors, according to research published online Jan. 12 in the Annals of Internal Medicine.
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Researchers ID Three New Glaucoma-Related Genes
TUESDAY, Jan. 12, 2016 (HealthDay News) — Three newly identified genes associated with primary open angle glaucoma bring the total number of such genes to 15, according to a study published online Jan. 11 in Nature Genetics.
Even Small Decline in Kidney Function Tied to CVD Risk
TUESDAY, Jan. 12, 2016 (HealthDay News) — Even a slight decline in kidney function can potentially lead to heart damage, according to research published online Jan. 11 in Hypertension.
USPSTF Recommends Biennial Screening Mammography
MONDAY, Jan. 11, 2016 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends biennial screening mammography for women aged 50 to 74 years. These findings form the basis of a final recommendation statement published online Dec. 12 in the Annals of Internal Medicine.
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Excessive Hair Growth Documented After IFN-β Tx
MONDAY, Jan. 11, 2016 (HealthDay News) — Excessive hair growth can occur after local administration of interferon (IFN)-β treatment for malignant melanoma, according to a letter to the editor published online Dec. 12 in the Journal of Dermatology.
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Measure of Outpatient Colonoscopy Quality Developed
MONDAY, Jan. 11, 2016 (HealthDay News) — A risk-adjusted measure of outpatient colonoscopy quality can help inform patient choices and assist in quality-improvement efforts, according to research published in the January issue of Gastroenterology.
Prevalence of Folate Deficiency 14.1 Percent in Multiple Myeloma
MONDAY, Jan. 11, 2016 (HealthDay News) — The prevalence of folate deficiency is 14.1 percent among patients with multiple myeloma (MM), according to a letter to the editor published online Dec. 19 in the International Journal of Laboratory Hematology.
Breast Implants Linked to Chronic Pulmonary Silicone Embolism
MONDAY, Jan. 11, 2016 (HealthDay News) — Chronic pulmonary silicone embolism related to saline breast implants has been detailed in a letter to the editor published in the January issue of the Annals of the American Thoracic Society.
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Reduction in Proximal, Distal Leg Muscle Strength in T2DM
MONDAY, Jan. 11, 2016 (HealthDay News) — For patients with type 2 diabetes mellitus (T2DM), proximal and distal leg muscle strength is reduced, and proximal but not distal muscle volume is also reduced, according to a study published online Jan. 6 in Diabetes Care.
Cardiomyopathy Etiology Impacts Catheter Ablation Outcomes
FRIDAY, Jan. 8, 2016 (HealthDay News) — For patients with atrial fibrillation (AF) and left ventricular systolic dysfunction, cardiomyopathy etiology impacts long term outcomes of catheter ablation, according to a study published online Dec. 28 in the Journal of Cardiovascular Electrophysiology.
Truncating Variant Prevalence Up in Peripartum Cardiomyopathy
FRIDAY, Jan. 8, 2016 (HealthDay News) — Women with peripartum cardiomyopathy have a prevalence of truncating variants similar to that seen in patients with dilated cardiomyopathy, according to a study published online Jan. 6 in the New England Journal of Medicine.
CDC: TB Potentially Passed From Zoo Elephants to People
FRIDAY, Jan. 8, 2016 (HealthDay News) — Transmission of tuberculosis from infected captive elephants to humans may be possible with long-term, close contact with the animals, according to research published in the Jan. 8 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.
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U.S. Cancer Mortality Rates Down 23 Percent Since 1991
THURSDAY, Jan. 7, 2016 (HealthDay News) — Since peaking in 1991, cancer mortality rates in the United States have dropped by 23 percent, according to findings included in Cancer Statistics, 2016, the American Cancer Society’s latest annual report on cancer incidence, mortality, and survival. The report was published online Jan. 7 in CA: A Cancer Journal for Clinicians.
Trio of Papers Reveal Lessons Learned From Ebola Epidemic
THURSDAY, Jan. 7, 2016 (HealthDay News) — A trio of papers published in the Jan. 7 issue of the New England Journal of Medicine reveal some of what has been learned about the Ebola virus.
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Blood Test May Help Rule Out Preeclampsia in Short Term
THURSDAY, Jan. 7, 2016 (HealthDay News) — A sFlt-1:PlGF ratio of 38 or lower appears to help rule out preeclampsia in women in whom the syndrome is suspected clinically, according to a study published in the Jan. 7 issue of the New England Journal of Medicine.
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Antibody Tx Reduces Graft-vs-Host Post Stem Cell Transplant
THURSDAY, Jan. 7, 2016 (HealthDay News) — Antibody therapy before stem cell transplant may benefit patients with acute leukemia, according to research published in the Jan. 7 issue of the New England Journal of Medicine.
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Dietary Glutamic Acid Linked to Lower Risk of Colorectal Cancer
THURSDAY, Jan. 7, 2016 (HealthDay News) — Dietary glutamic acid intake is associated with reduced risk of developing colorectal cancer (CRC), according to a study published online Dec. 30 in Cancer.
African-American Men Produce Less Prostate-Specific Antigen
THURSDAY, Jan. 7, 2016 (HealthDay News) — Among men with Gleason score 3+3=6 prostate cancer, African-Americans produce less prostate-specific antigen than Caucasians, according to a study published in the February issue of The Journal of Urology.
Role of Pathogenic Variants in Arrhythmia Genes Unclear
WEDNESDAY, Jan. 6, 2016 (HealthDay News) — Potentially pathogenic genetic variants in arrhythmia susceptibility genes are not associated with an abnormal phenotype, according to a study published in the Jan. 5 issue of the Journal of the American Medical Association.
Early-Life Exercise May Promote Lifelong Brain Function
WEDNESDAY, Jan. 6, 2016 (HealthDay News) — Early-life exercise-induced alterations in gut microbiota may promote brain function and emotional well-being, according to a study published online Dec. 9 in Immunology & Cell Biology.
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Novel Antigen Implicated in Immediate Hypersensitivity to Beer
WEDNESDAY, Jan. 6, 2016 (HealthDay News) — A novel antigen, which belongs to the protein Z family, may be involved in immediate hypersensitivity to beer, according to a case report published online Dec. 12 in the Journal of Dermatology.
Inherited Mutations in 18 Percent With Ovarian Cancer
WEDNESDAY, Jan. 6, 2016 (HealthDay News) — Pathogenic germline mutations are common in women with ovarian, fallopian tube, and peritoneal carcinoma (OC), according to a study published online Dec. 30 in JAMA Oncology.
Pesticide in Milk Years Ago May Be Linked to Signs of Parkinson’s
TUESDAY, Jan. 5, 2016 (HealthDay News) — Men who drank milk that may have been tainted with a pesticide when they were young might be more likely to develop signs of Parkinson’s disease, according to a study published online Dec. 9 in Neurology.
Researchers Calculate Family Risk Estimates for Cancer
TUESDAY, Jan. 5, 2016 (HealthDay News) — Having an identical twin diagnosed with cancer increases the other twin’s risk of developing not just that type but any form of cancer, according to research published in the Jan. 5 issue of the Journal of the American Medical Association.
Signs of CTE in Brain of Deceased 25-Year-Old Football Player
TUESDAY, Jan. 5, 2016 (HealthDay News) — A case report published online Jan. 4 in JAMA Neurology highlights a neuropsychological test profile conducted on a patient with chronic traumatic encephalopathy (CTE).
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Axillary pCR Linked to Improved Breast Cancer Survival
TUESDAY, Jan. 5, 2016 (HealthDay News) — For women with breast cancer treated with primary systemic chemotherapy (PST), achieving axillary pathologic complete response (pCR) is associated with improved survival, according to a study published online Dec. 30 in JAMA Oncology.
Support for First-Line Erlotinib in NSCLC With EGFR Mutations
MONDAY, Jan. 4, 2016 (HealthDay News) — For patients with non-small-cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) mutations, erlotinib is active, and treatment beyond progression is feasible and may delay salvage therapy in selected patients, according to a study published online Dec. 30 in JAMA Oncology.
Diagnostic Factors May Help Patients Avoid Prostate Biopsy
MONDAY, Jan. 4, 2016 (HealthDay News) — Initial diagnostic characteristics may be able to identify men initiating active surveillance who could avoid confirmatory biopsy, according to a study published in the January issue of The Journal of Urology.
β-Genus Human Papillomavirus Poses Skin Cancer Risk
MONDAY, Jan. 4, 2016 (HealthDay News) — β-genus human papillomavirus (β-HPV) is a risk factor for cutaneous squamous cell carcinoma (cSCC) in otherwise healthy individuals, according to a review published online Dec. 30 in JAMA Dermatology.
CDC: Heart Failure Mortality Up 2012 Through 2014
MONDAY, Jan. 4, 2016 (HealthDay News) — The age-adjusted mortality rates from heart failure decreased from 2000 to 2012 but increased from 2012 through 2014, according to a December data brief published by the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics.
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