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Risk for Emergently Treated Hypocalcemia With Denosumab Rises With CKD Stage

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Risk increased with worsening CKD stage with denosumab versus bisphosphonates; highest risk seen for dialysis-dependent CKD, CKD-mineral and bone disorder

ACR: Inebilizumab Reduces Risk for Flares in IgG4-Related Disease

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Flare-free, treatment-free complete remission and flare-free, glucocorticoid-free complete remission improved with inebilizumab

Oral Infigratinib Seems Safe for Children With Achondroplasia

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At dose of 125 mg/kg body weight, oral infigratinib results in increased annualized height velocity and z score

Beta Blockers May Cause Depressive Symptoms

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Findings seen in patients following myocardial infarction

ChemoRT Then Immunochemotherapy Then Surgery Promising in Unresectable Esophageal Cancer

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One-year progression-free survival, overall survival was 79.4, 89.6 percent; significantly longer survival seen in patients who achieved resectability

Tirzepatide Yields Sustained Weight Reduction in Obesity, Prediabetes

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Three years of tirzepatide also reduced risk for progression to type 2 diabetes compared with placebo

Bleeding Risk Increased With NSAID Use for VTE Patients Receiving Anticoagulants

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More than twofold increased bleeding rate seen with NSAID use for patients treated with oral anticoagulants for VTE

Global Coverage With Measles Vaccine Declined During COVID-19

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From 2022 to 2023, there was a 20 percent increase in estimated measles cases worldwide, from 8,645,000 to 10,341,000

Metformin Use Tied to Lower Rate of Asthma Attacks

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Further reductions seen with the use of glucagon-like peptide-1 receptor agonists

Gabapentinoid Use Tied to Higher Risk for Hip Fractures

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Associations especially strong in patients who are frail or have chronic kidney disease