Correlation with cardiovascular death, all-cause mortality remained significant after adjustment
MONDAY, Aug. 8, 2016 (HealthDay News) — Periodontitis is associated with increased incidence of cardiovascular disease (CVD) and all-cause mortality, according to a study published in the Aug. 15 issue of The American Journal of Cardiology.
Gorm Mørk Hansen, M.D., from the University of Copenhagen in Denmark, and colleagues identified a nationwide cohort of 17,691 patients who received a hospital diagnosis of periodontitis and matched them with 83,003 controls using Danish national registers. The authors examined the incidence rate ratios of myocardial infarction, ischemic stroke, cardiovascular death, major adverse cardiovascular events, and all-cause mortality.
The researchers found that patients with periodontitis were at higher risk of all examined end points. After adjustment for increased baseline comorbidity, the results remained significant, with adjusted incidence rate ratios of 2.02 and 2.70 for cardiovascular death and all-cause mortality, respectively. A high burden of comorbidity was seen for patients with a hospital diagnosis of periodontitis, and they also had increased risk of CVD and all-cause mortality.
“In conclusion, our results support that periodontitis may be an independent risk factor for CVD,” the authors write.
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