75.03 percent of children undergoing oral food challenge achieved tolerance to some kind of fish
MONDAY, Oct. 30, 2017 (HealthDay News) — Fish is an important trigger of food protein-induced enterocolitis syndrome (FPIES), according to a study published online Oct. 20 in Allergy.
Sonsoles Infante, M.D., from Hospital Infantil Universitario Gregorio Marañón in Spain, and colleagues assessed the evolution and follow-up of FPIES related to fish over a 20-year period. Data were included for 80 children diagnosed with FPIES by fish, with diagnosis based on Sicherer’s criteria.
The researchers found that the most frequently involved fish were hake, megrim, and sole (87.5, 31.25, and 23.75 percent). Of the patients, 56.25, 28.75, and 15 percent, respectively, reacted to one unique fish, two different fish, and three or more different fish. The number of reactions before diagnosis was four on average. The main symptoms at the debut were vomiting and vomiting with diarrhea (97.5 and 30 percent, respectively), which occurred in a mean time of 126.3 minutes after ingestion of the culprit fish. One hundred seventy-three oral food challenges were performed in 60 of the patients. Overall, 75.03 percent achieved tolerance to some kind of fish: 41.7 percent overcame their FPIES and 33.33 percent tolerated another type of fish. Twenty-five percent of patients challenged did not tolerate any fish during the oral food challenge.
“In our population fish is, by far, the solid food most implicated in FPIES,” the authors write.
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