Home Pathology December 2015 Briefing – Pathology

December 2015 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for December 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

AMA: Burnout Is Top Issue for Physicians in 2015

WEDNESDAY, Dec. 30, 2015 (HealthDay News) — Physician burnout is the top issue for physicians in 2015, according to a report published by the American Medical Association (AMA).

Alcohol Binge Damage May Be Worse Than Previously Thought

WEDNESDAY, Dec. 30, 2015 (HealthDay News) — Chronic drinking combined with binge drinking may be more destructive than previously thought, according to an animal study published online Nov. 20 in Biomolecules.

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Antimicrobial Stewardship Improves Outcomes for MRSA

WEDNESDAY, Dec. 30, 2015 (HealthDay News) — For patients receiving antimicrobial injections targeting methicillin-resistant Staphylococcus aureus (MRSA), implementation of an antimicrobial stewardship program that includes daily review of prescriptions is associated with improved clinical outcomes, according to a study published online Dec. 18 in the Journal of Clinical Pharmacy and Therapeutics.

Secretory IgA Secretion Rate Linked to Risk of Cancer Death

WEDNESDAY, Dec. 30, 2015 (HealthDay News) — Higher secretion rates of secretory immunoglobulin A (sIgA) are associated with decreased risk of cancer death, specifically non-lung cancer, according to a study published online Dec. 23 in PLOS ONE.

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Third-Trimester Screen Detects Late Alloimmunization

WEDNESDAY, Dec. 30, 2015 (HealthDay News) — Third-trimester screening for alloimmunization in Rhesus c (Rhc)-negative women improves detection and treatment of hemolytic disease of the fetus and newborn (HDFN), according to a study published online Dec. 11 in BJOG: An International Journal of Obstetrics and Gynaecology.

Study Strengthens Evidence for Mycoplasma genitalium As STI

TUESDAY, Dec. 29, 2015 (HealthDay News) — Mycoplasma genitalium (MG) is prevalent in more than 1 percent of the sexually-experienced British population, with no infections detected in those reporting no previous sexual experience, according to a study published online Nov. 3 in the International Journal of Epidemiology.

Early First Cancer in BRCA1/2 Ups Risk in Opposite Breast

TUESDAY, Dec. 29, 2015 (HealthDay News) — BRCA1/2 mutation carriers have increased risk of contralateral breast cancer (CBC), with age at first diagnosis a significant predictor of CBC risk, according to a study published online Dec. 23 in the Journal of Clinical Oncology.

Impact of 2012 USPSTF Guideline Against PSA Screening Explored

TUESDAY, Dec. 29, 2015 (HealthDay News) — Patients undergoing prostate needle biopsies after the 2012 U.S. Preventive Services Task Force (USPSTF) recommendation against prostate-specific antigen-based screening for prostate cancer for men of any age are more likely to be diagnosed with high-risk disease, according to research published in the January issue of The Journal of Urology.

Higher Hospital Prices in U.S. ‘Monopoly Markets’

MONDAY, Dec. 28, 2015 (HealthDay News) — Prices at hospitals in monopoly markets are 15 percent higher than those at hospitals in areas with at least four providers, according to research published recently at the Health Care Pricing Project website.

Modifiable Factors Affect Racial Differences in Lung Cancer

MONDAY, Dec. 28, 2015 (HealthDay News) — Racial/ethnic variation is evident in lung cancer incidence and mortality among postmenopausal women, but other factors may have an influence, according to a study published online Dec. 23 in the Journal of Clinical Oncology.

Infusion of HIV-Neutralizing Antibody Decreases Viremia

FRIDAY, Dec. 23, 2015 (HealthDay News) — A single infusion of the potent human monoclonal antibody (mAb) targeting the HIV-1 CD4 binding site, VRC01, decreases plasma viremia, according to a study published in the Dec. 23 issue of Science Translational Medicine.

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Experimental Mood Induction Impacts IL-18 Levels

WEDNESDAY, Dec. 23, 2015 (HealthDay News) — Experimental mood induction changes interleukin (IL)-18 levels and is associated with changes in central opioid neurotransmission, according to a study published recently in Molecular Psychiatry.

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FDA Lifts Ban on Blood Donations by Men Who Have Sex With Men

TUESDAY, Dec. 22, 2015 (HealthDay News) — Men who have sex with men who have abstained from sex for one year will now be allowed to donate blood in the United States. The new policy, announced Monday by the U.S. Food and Drug Administration, reverses a three-decades-old ban on donations from this group of men that traces back to the start of the AIDS epidemic.

Meta-Analysis Confirms miR-21 Expression, Laryngeal CA Link

TUESDAY, Dec. 22, 2015 (HealthDay News) — Expression of miR-21 is associated with laryngeal carcinoma, with high expression related to increased laryngeal cancer risk, according to a meta-analysis published online Dec. 12 in the Journal of Evidence-Based Medicine.

Specific, Consistent ICD-10 Coding Key to Timely Payments

TUESDAY, Dec. 22, 2015 (HealthDay News) — In order to prevent denials, it is important to code correctly within the International Classification of Diseases, Tenth Revision (ICD-10), with specificity matching documentation, according to an article published in Medical Economics.

Neural Effects of Psychotherapy in Personality Disorder ID’d

TUESDAY, Dec. 22, 2015 (HealthDay News) — Transference-focused psychotherapy (TFP) is associated with alterations in frontolimbic circuitry in borderline personality disorder (BPD), according to a study published online recently in Psychiatry and Clinical Neurosciences.

Periodontal Disease Linked to Increased Breast Cancer Risk

MONDAY, Dec. 21, 2015 (HealthDay News) — Periodontal disease is associated with increased risk of breast cancer among postmenopausal women, according to research published online Dec. 21 in Cancer, Epidemiology, Biomarkers & Prevention.

Affordable Care Act Has Improved Access to Care, Affordability

MONDAY, Dec. 21, 2015 (HealthDay News) — Implementation of the Affordable Care Act has improved access to care and affordability of care for many adults, according to a study published in the December issue of Health Affairs.

Increase in Alcohol Tax Linked to Reduction in Gonorrhea Rates

MONDAY, Dec. 21, 2015 (HealthDay News) — Introduction of an increase in alcohol beverage sales tax is associated with a reduction in gonorrhea rates, according to research published online Dec. 9 in the American Journal of Preventive Medicine.

Intra-Pancreatic Triacylglycerol Drops With Weight Loss in T2DM

MONDAY, Dec. 21, 2015 (HealthDay News) — The weight loss-associated decrease in intra-pancreatic triacylglycerol which occurs after gastric bypass is specific to type 2 diabetes mellitus (T2DM), according to a study published online Dec. 1 in Diabetes Care.

Acral Pigmented Lesions More Common on Darker Skin

FRIDAY, Dec. 18, 2015 (HealthDay News) — People with darker skin are about one-third more likely to have acral pigmented lesions on their palms and soles, according to a study published online Dec. 14 in the Journal of the American Academy of Dermatology.

Over Half of U.S. States Ill Prepared for Disease Outbreaks

FRIDAY, Dec. 18, 2015 (HealthDay News) — More than half of U.S. states are poorly prepared to respond to infectious disease outbreaks, according to a new report released Dec. 17 by the Trust for America’s Health (TFAH) and the Robert Wood Johnson Foundation.

Age at NSCLC Diagnosis Tied to Odds of Targetable Phenotype

FRIDAY, Dec. 18, 2015 (HealthDay News) — For patients with non-small-cell lung cancer (NSCLC), younger age at diagnosis is associated with increased frequency of a targetable phenotype, according to a study published online Dec. 17 in JAMA Oncology.

Ultrasound Findings in Invasive Breast CA Link to Histopathology

FRIDAY, Dec. 18, 2015 (HealthDay News) — Histopathologic patterns and biomarkers for invasive breast cancer correlate with differences in findings on sonographic (US) imaging, according to a study published in the January issue of the Journal of Clinical Ultrasound.

Longer Follow-Up Needed to Evaluate Ovarian CA Screening

THURSDAY, Dec. 17, 2015 (HealthDay News) — The efficacy of ovarian cancer screening is unclear, with no significant reduction in mortality in primary analysis, according to a study published online Dec. 17 in The Lancet.

Antineoplastic Agent Obscures Diagnosis of Fungal Meningitis

THURSDAY, Dec. 17, 2015 (HealthDay News) — A case of cryptococcal meningitis with false-negative cerebrospinal fluid (CSF) culture results following receipt of capecitabine has been described in a case report published in the December issue of the Journal of Clinical Pharmacy and Therapeutics.

Roughly Half of U.S. Hospitals Require Staff Flu Vaccination

WEDNESDAY, Dec. 16, 2015 (HealthDay News) — The majority of U.S. hospitals don’t require health care providers to get a seasonal flu vaccine, according to a study published online Nov. 27 in Infection Control and Hospital Epidemiology.

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Industry Outpacing NIH in Funding Research

WEDNESDAY, Dec. 16, 2015 (HealthDay News) — There’s been a sharp rise in the number of industry-funded clinical trials and a significant decline in those financed by the U.S. government in recent years, according to findings published in the Dec. 15 issue of the Journal of the American Medical Association.

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Risk of CV Events Up After Shingles Diagnosis in Seniors

WEDNESDAY, Dec. 16, 2015 (HealthDay News) — Stroke risk appears to more than double in the first week following a shingles diagnosis, with myocardial infarction (MI) risk also climbing, though not by quite as much, according to research published online Dec. 15 in PLOS Medicine.

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HSCT Not Linked to Sustained Remission in Refractory Crohn’s

WEDNESDAY, Dec. 16, 2015 (HealthDay News) — For adult patients with refractory Crohn’s disease with impaired quality of life, autologous hematopoietic stem cell transplantation (HSCT) is not associated with sustained disease remission at one year, according to a study published in the Dec. 15 issue of the Journal of the American Medical Association.

Nasal, Pharyngeal EPX Levels Linked to Sputum Eosinophilia

WEDNESDAY, Dec. 16, 2015 (HealthDay News) — For individual patients with poorly-controlled asthma, nasal and pharyngeal eosinophil peroxidase (EPX) levels are strongly associated with the eosinophil percentage of induced sputum, according to a study published online Dec. 8 in Allergy.

c-Jun N-terminal Kinase Essential for HSV Reactivation

WEDNESDAY, Dec. 16, 2015 (HealthDay News) — Activation of c-Jun N-terminal kinase (JNK) is essential for herpes simplex virus (HSV) gene expression during virus reactivation from latent neuronal infection, according to a study published in the Dec. 9 issue of Cell Host & Microbe.

Dose-Linked Pulmonary Complications After FFP Infusion

TUESDAY, Dec. 15, 2015 (HealthDay News) — About 20 percent of patients administered fresh frozen plasma (FFP) to reverse warfarin anticoagulation develop pulmonary complications, with highest risk seen with more than three units of FFP, according to a study published online Dec. 8 in the Journal of Thrombosis and Haemostasis.

Uptake of ‘Western Lifestyle’ Tied to Rising Cancer Rates

TUESDAY, Dec. 15, 2015 (HealthDay News) — Better screening and lifestyle changes have helped to reduce the prevalence of common cancers in many high-income countries, but low- and middle-income countries are seeing those rates rise as they adopt unhealthy Western habits, according to a report published online Dec. 14 in Cancer Epidemiology, Biomarkers & Prevention.

USPSTF: Screen All Teens, Adults at Risk for Syphilis

TUESDAY, Dec. 15, 2015 (HealthDay News) — All adults and teens at increased risk for syphilis should be screened for the sexually transmitted disease, a U.S. Preventive Services Task Force (USPSTF) draft recommendation says. The recommendation complements a 2009 task force recommendation that all pregnant women be screened for syphilis.

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Platelet Counts Rise With Viral Response to Hep C Therapy

TUESDAY, Dec. 15, 2015 (HealthDay News) — Platelet counts rise among patients with chronic hepatitis C virus (HCV) infection who experience a sustained virological response (SVR) to antiviral therapy, according to research published online Dec. 8 in the Journal of Gastroenterology and Hepatology.

Salty Food Intake Tied to Acne Development

TUESDAY, Dec. 15, 2015 (HealthDay News) — Consuming salty foods may be a significant factor contributing to the development of acne, according to a study published online Dec. 9 in the Journal of Cosmetic Dermatology.

Early Chemo Less Likely to Help Black Breast Cancer Patients

MONDAY, Dec. 14, 2015 (HealthDay News) — Neoadjuvant chemotherapy is less likely to benefit black women with breast cancer than those in other racial and ethnic groups, according to a study published online Nov. 23 in the Journal of Clinical Oncology.

New Model of Inpatient Care Can Improve Outcomes

MONDAY, Dec. 14, 2015 (HealthDay News) — Implementation of a new model of care can improve outcomes of care in medical and surgical units, according to a study published in the December issue of the Journal of Hospital Medicine.

CYP2C19 Polymorphisms Impacts Citalopram Metabolism

MONDAY, Dec. 14, 2015 (HealthDay News) — For patients with major depressive disorder, certain CYP2C19 polymorphisms contribute to citalopram (CIT) metabolism, according to research published in the December issue of the Journal of Clinical Pharmacy and Therapeutics.

Hepatitis E Virus Rare Among HIV-Infected Population

MONDAY, Dec. 14, 2015 (HealthDay News) — The prevalence of hepatitis E virus (HEV) is low in HIV-infected (HIV+) women and men, according to a study published online Dec. 8 in Hepatology.

MITF p.E318K Prevalence Similar, Regardless of CDKN2A

FRIDAY, Dec. 11, 2015 (HealthDay News) — The prevalence of MITF p.E318K is similar in patients with melanoma, irrespective of the presence of CDKN2A mutations, according to a study published online Dec. 10 in JAMA Dermatology.

Seven Behaviors Suggested to Improve ‘Art of Medicine’

FRIDAY, Dec. 11, 2015 (HealthDay News) — Seven behaviors should be implemented to improve the art of medicine, which can help improve relationships with patients, according to an article published in Family Practice Management.

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Noninvasive Scan Promising Alternative to Biopsy in Skin CA

THURSDAY, Dec. 10, 2015 (HealthDay News) — A team from Germany now reports that a new audio-visual imaging technique looks as effective as surgery for identifying melanoma metastasis. The findings were published in the Dec. 9 issue of Science Translational Medicine.

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Excessive Testing May Be Compromising T2DM Care

THURSDAY, Dec. 10, 2015 (HealthDay News) — Many Americans with type 2 diabetes may be getting unnecessary tests — and, in some cases, needless changes in medication, according to a study published online Dec. 8 in The BMJ.

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Cell-Free Circulating mtDNA Identifies Parkinson’s Disease

THURSDAY, Dec. 10, 2015 (HealthDay News) — Cell-free circulating mitochondrial DNA (ccf-mtDNA) from cerebrospinal fluid (CSF) is reduced in patients with Parkinson’s disease (PD), according to research published in the December issue of the Annals of Neurology.

Percentage of Graduates Entering GME Stable Over Past Decade

WEDNESDAY, Dec. 9, 2015 (HealthDay News) — Despite an increase in the number of U.S. medical school graduates, over the past decade the percentage entering graduate medical education (GME) training has remained stable, according to a research letter published in the Dec. 8 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Depression Not Uncommon Among Resident Physicians

WEDNESDAY, Dec. 9, 2015 (HealthDay News) — More than one in four doctors-in-training may be depressed, which could put their patients at risk, according to a study published in the Dec. 8 issue of the Journal of the American Medical Association, a theme issue on medical education.

Med Ed Can Be Improved for High-Value, Cost-Conscious Care

TUESDAY, Dec. 8, 2015 (HealthDay News) — The combination of effective transmission of knowledge, facilitation of reflective practice, and a supportive environment can educate physicians to deliver high-value, cost-conscious care, according to a review published in the Dec. 8 issue of the Journal of the American Medical Association, a theme issue on medical education.

FDA Approves Kanuma for Lysosomal Acid Lipase Deficiency

TUESDAY, Dec. 8, 2015 (HealthDay News) — Kanuma (sebelipase alfa) has been approved by the U.S. Food and Drug Administration as the first treatment for LAL deficiency (Wolman disease or cholesteryl ester storage disease).

CDC: Fewer Americans Struggling With Medical Bills

TUESDAY, Dec. 8, 2015 (HealthDay News) — Fewer American families are struggling to pay medical bills, according to a report from the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics (NCHS).

Recurrent Aphthous Stomatitis Linked to Oxidative Stress

TUESDAY, Dec. 8, 2015 (HealthDay News) — Recurrent aphthous stomatitis is associated with increased total oxidative status and oxidative stress index values, according to a study published online Dec. 1 in the International Journal of Dermatology.

ADT for Prostate CA Tied to Increased Alzheimer’s Risk

TUESDAY, Dec. 8, 2015 (HealthDay News) — Androgen deprivation therapy (ADT) for prostate cancer might dramatically increase a man’s risk of developing Alzheimer’s disease, a large-scale analysis of health data suggests. The study was published online Dec. 7 in the Journal of Clinical Oncology.

U.S. Health Care Spending Increased in 2014

TUESDAY, Dec. 8, 2015 (HealthDay News) — The expansion of insurance coverage and increases in retail prescription drug spending contributed to an increase in total national health care expenditures in 2014, according to a report published online Dec. 2 in Health Affairs.

AAP: Screen All Children for Cholesterol, Depression, HIV

MONDAY, Dec. 7, 2015 (HealthDay News) — All children should be screened for high cholesterol, depression, and HIV, with some tests starting as early as age 9, according to new guidelines from the American Academy of Pediatrics published online Dec. 7 in Pediatrics.

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Etiology of Leukemia in Breast Cancer Survivors Explored

MONDAY, Dec. 7, 2015 (HealthDay News) — Researchers are zeroing in on factors that may increase the risk of leukemia after breast cancer treatment, according to a report published online Dec. 7 in Cancer.

AFP Levels Predict Fibrosis Regression After SVR in Hep C

MONDAY, Dec. 7, 2015 (HealthDay News) — For patients with chronic hepatitis C virus (HCV), lower post-treatment α-fetoprotein (AFP) levels and HCV genotype 2 correlate with liver fibrosis regression after sustained virological response (SVR), according to a study published online Dec. 3 in the Journal of Gastroenterology and Hepatology.

Omega-3 Fatty Acids May Play Role in Bipolar Disorder

MONDAY, Dec. 7, 2015 (HealthDay News) — There may be a link between levels of omega-3 fatty acids and bipolar disorder, according to a small study published in the November issue of Bipolar Disorders.

Guidelines Developed for Perinatal Hematologic Cancers

MONDAY, Dec. 7, 2015 (HealthDay News) — Consensus guidelines have been developed for clinical management of hematologic malignancies during the perinatal period, according to a special article published online Nov. 30 in the Journal of Clinical Oncology.

Statin Treatment Linked to Reduced Risk of Cataracts

MONDAY, Dec. 7, 2015 (HealthDay News) — Statin treatment is associated with reduced risk of incident cataract development, according to a study published in the Dec. 15 issue of The American Journal of Cardiology.

Metformin Linked to Beneficial Changes in Gut Bacteria

FRIDAY, Dec. 4, 2015 (HealthDay News) — Metformin appears to trigger favorable changes in intestinal bacteria, according to a study published online Dec. 2 in Nature.

Low-Risk Prostate CA Patients May Not Be Monitored Properly

FRIDAY, Dec. 4, 2015 (HealthDay News) — Many men with low-risk prostate cancer who choose active surveillance may not be followed as closely as they should be, according to a study published in the Dec. 1 issue of Cancer.

Time to Tx Initiation Impacts Survival in Head, Neck Cancer

FRIDAY, Dec. 4, 2015 (HealthDay News) — For patients with head and neck squamous cell carcinoma, time to treatment initiation (TTI) impacts overall survival, according to a study published online Nov. 30 in the Journal of Clinical Oncology.

Glove-Related Hand Urticaria May Be Rising in Health Care Workers

FRIDAY, Dec. 4, 2015 (HealthDay News) — Health care workers are at high risk of glove-related hand urticaria, an occupational issue that may be increasing, according to a research letter published online Nov. 27 in the British Journal of Dermatology.

AMA: Case Before Supreme Court Threatens Patient Privacy

THURSDAY, Dec. 3, 2015 (HealthDay News) — A case before the Supreme Court is potentially threatening patient confidentiality, according to the American Medical Association (AMA).

Plasma Prekallikrein May Be Vascular Risk Factor in T1DM

THURSDAY, Dec. 3, 2015 (HealthDay News) — Plasma prekallikrein (PK) is associated with vascular disease risk in type 1 diabetes, according to a study published online Nov. 24 in Diabetes.

Anthracyclines More Neurotoxic Than Other Breast CA Regimens

THURSDAY, Dec. 3, 2015 (HealthDay News) — For breast cancer survivors, anthracyclines seem to have greater negative effects on certain cognitive domains and brain network connections than nonanthracycline regimens, according to a study published online Dec. 3 in JAMA Oncology.

False-Positive Mammogram May Hint at Breast Cancer Risk Later

THURSDAY, Dec. 3, 2015 (HealthDay News) — Women who receive a false-positive result on a mammogram may be at increased risk of developing breast cancer later, according to research published online Dec. 2 in Cancer Epidemiology, Biomarkers & Prevention.

Evidence Doesn’t Support Monthly Labs With Isotretinoin

THURSDAY, Dec. 3, 2015 (HealthDay News) — Less frequent laboratory monitoring may be safe for patients receiving isotretinoin for acne as changes in mean values of several laboratory tests do not meet a priori criteria for high-risk, according to research published online Dec. 2 in JAMA Dermatology.

Carpal Tunnel Syndrome Up With Overweight, Obesity

THURSDAY, Dec. 3, 2015 (HealthDay News) — Overweight and obesity are associated with increased risk of carpal tunnel syndrome (CTS) and carpal tunnel release, according to a meta-analysis published in the December issue of Obesity Reviews.

Survival Up for Patients With Stage IV Breast Cancer

WEDNESDAY, Dec. 2, 2015 (HealthDay News) — American women diagnosed with advanced, stage IV breast cancer have a better chance of survival, and are surviving longer, compared to two decades ago, according to a study published online Dec. 2 in JAMA Surgery.

Levels of Ebola Virus in Blood Could Help Predict Mortality

WEDNESDAY, Dec. 2, 2015 (HealthDay News) — The levels of Ebola virus in a patient’s blood can strongly predict the mortality risk, according to a study published online Dec. 1 in PLOS Medicine.

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Burnout Rates on the Rise for Physicians

WEDNESDAY, Dec. 2, 2015 (HealthDay News) — Burnout is a growing problem among American doctors, according to research published in the December issue of the Mayo Clinic Proceedings.

Asthma Risk Up Slightly for Planned C-Section Children

WEDNESDAY, Dec. 2, 2015 (HealthDay News) — Children born by planned cesarean delivery appear to have slightly higher odds of developing asthma than those born through vaginal delivery, researchers report in the Dec. 1 issue of the Journal of the American Medical Association.

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Burden, Costs of Gastrointestinal, Liver Disease Estimated in U.S.

WEDNESDAY, Dec. 2, 2015 (HealthDay News) — In the United States, the burden and associated costs of gastrointestinal (GI), liver, and pancreatic diseases are substantial, according to a report published in the December issue of Gastroenterology.

USPSTF: Insufficient Evidence for Visual Skin Cancer Screening

WEDNESDAY, Dec. 2, 2015 (HealthDay News) — The U.S. Preventive Services Task Force has found that there is currently insufficient evidence to weigh the benefits and harms of visual skin cancer screening in adults. These findings form the basis of a draft recommendation statement published online Nov. 30 by the USPSTF.

Draft Evidence Review
Draft Recommendation Statement
Comment on Recommendation

CDC: Cholesterol Levels Improving But More Work Needed

TUESDAY, Dec. 1, 2015 (HealthDay News) — About one in every eight American adults continue to have high levels of total cholesterol, while even more have low levels of high-density lipoprotein (HDL) cholesterol, according to a December data brief published by the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics.

Endurance Exercise Accelerates Pathology With Gene Mutation

TUESDAY, Dec. 1, 2015 (HealthDay News) — Endurance exercise seems to accelerate arrhythmogenic ventricular cardiomyopathy (AVC) pathogenesis in transgenic mice with the desmoplakin R2834H mutation (Tg-DSPR2834H), according to an experimental study published online Nov. 6 in the American Journal of Physiology: Heart and Circulatory Physiology.

Factors ID’d for Fine Needle Aspiration Diagnostic Accuracy

TUESDAY, Dec. 1, 2015 (HealthDay News) — Factors that can independently predict fine needle aspiration (FNA) diagnosis for follicular variant papillary thyroid carcinoma (FVPTC) as suspicious malignancy or malignant have been identified, according to research published online Nov. 18 in Head & Neck.

Chikungunya Virus Deemed Significant Cause of CNS Disease

TUESDAY, Dec. 1, 2015 (HealthDay News) — A 2005 to 2006 chikungunya outbreak on Reunion Island, east of Madagascar in the Indian Ocean, affected more than 300,000 people, with a higher-than-expected rate of encephalitis, researchers report online Nov. 25 in Neurology.

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