Those with interstitial cystitis show worse symptom severity, bladder function
By Lori Solomon HealthDay Reporter
FRIDAY, Jan. 3, 2025 (HealthDay News) — Interstitial cystitis and bladder pain syndrome (IC/BPS) vary in clinical manifestation, according to a study published online Oct. 18 in the International Journal of Urology.
Aya Niimi, M.D., Ph.D., from the University of Tokyo, and colleagues used patient registry data to describe clinical manifestations of patients with IC and BPS. The analysis included data from 529 patients seen at 14 university hospitals.
According to the researchers, 66.5 percent of the cases were classified as IC and 33.5 percent as BPS. IC patients were significantly older, were more likely female, and had more prevalent comorbidities, including autoimmune diseases. IC patients had significantly worse symptom severity, quality-of-life impairment, and bladder function. Urinary frequency on the frequency-volume chart was 18.8 times and 15.0 times higher for IC and BPS patients, respectively, and maximum voided volume was 160.9 and 214.1 mL, respectively. Bladder capacity under anesthesia was 293.8 and 472.6 mL, respectively. Pain in IC patients was significantly predicted by maximum voided volume and the number of Hunner lesions.
“This large-scale study highlighted different characteristics of IC and BPS, providing useful information to understand the etiology and management of IC/BPS,” the authors write.
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