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FDA Approves New Antibiotic for Uncomplicated Urinary Tract Infections

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Approval of Pivya is for female adults with UTIs caused by susceptible isolates of E. coli, P. mirabilis, and S. saprophyticus

Multisite QI Collaborative Increases Appropriate Pediatric Antibiotic Use

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Increase seen in median adherence to empirical, definitive, and duration of antibiotic therapy during intervention period

Cabozantinib Promising for Metastatic Pheochromocytomas, Paragangliomas

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Overall response rate was 25.0 percent in phase 2 study involving 17 patients

Impaired Fecundity Rate in Women Unchanged From 2011 to 2019

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However, infertility among married women ages 15 to 44 years rose

New Prostate Cancer Urine Test Has High Diagnostic Accuracy

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Higher AUROC seen for 18-gene MPS2 model compared with current guideline-endorsed biomarkers

Hospital Mortality Lower for Patients Treated by Female Physicians

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Benefit of receiving treatment from female physicians larger for female than male patients

Computer Prompts Could Reduce Empiric Antibiotic Use for UTI

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17.4 percent reduction seen in empiric extended-spectrum days of therapy, with no increase in safety outcomes

Transient Increase Seen in Contraceptive Use After Dobbs Decision

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Temporary increase seen in month after Dobbs, followed by decrease in contraceptive services, apart from vasectomy

HYPORT Noninferior for GU, GI Toxicity in Prostate Cancer

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24-month differences in genitourinary and gastrointestinal change scores were noninferior for HYPORT versus COPORT

Single Invitation for PSA Screening Cuts Prostate Cancer Deaths

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Small, but significant reduction seen in prostate cancer deaths, but no reduction seen in all-cause mortality