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Two decision instruments have high sensitivity for identifying blunt trauma patients with clinically significant thoracic injuries

Two Decision Instruments ID Major Injuries in Blunt Trauma

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Decision instruments have high sensitivity for identifying clinically significant thoracic injuries
The U.S. Food and Drug Administration has approved Opdivo (nivolumab) to treat patients with advanced non-small-cell lung cancer whose disease progressed despite platinum-based chemotherapy.

FDA Approves Expanded Use of Opdivo in Advanced Lung Cancer

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Demonstrates survival benefit in both squamous and non-squamous non-small-cell lung cancer
Most patients undergoing surgery for lung or colorectal cancer believe that the surgery is likely to be curative

Most Cancer Patients Believe Surgery Will Be Curative

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Findings even among patients with stage IV lung, colorectal cancer
Overweight and mildly obese women with heart failure may live significantly longer than similarly heavy men with the progressive disease

Being Overweight Helps Women With Heart Failure, but Not Men

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Women with a BMI between 25 and 29.9 kg/m² have the greatest survival advantage
Early noninvasive ventilation does not reduce mortality compared with oxygen therapy alone for immunocompromised patients admitted to the intensive care unit with hypoxemic acute respiratory failure. These findings were published online Oct. 7 in the Journal of the American Medical Association to coincide with the annual meeting of the European Society of Intensive Care Medicine

Early Noninvasive Ventilation Doesn’t Cut Mortality in ICU

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No reduction in mortality versus oxygen therapy alone for immunocompromised patients
The Global Lung Initiative-defined normal spirometry includes adjusted mean values in the normal range for multiple phenotypes

‘GOLD’ Criteria May Misdiagnosis Normal Phenotypes

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Among adults with GLI-defined normal spirometry
The Guidelines International Network has developed principles for disclosure and management of conflicts of interest during the clinical practice guideline development process

Guidelines Developed for Managing Conflicts of Interest

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Core principles developed for managing COIs during the clinical practice guideline development process
In patients with heart failure with preserved ejection fraction

Nitrites Aid Heart Failure With Preserved Ejection Fraction

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Sodium nitrite reduces hemodynamic derangements of cardiac failure that occur with exercise
For intensive care unit (ICU) patients with fever due to probable infection

Acetaminophen Given Early Doesn’t Cut ICU Days

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No impact on number of ICU-free days in patients with fever due to probable infection
Modification of the traditional Subjective-Objective-Assessment-Plan presentation to consider value can help medical students learn to practice high-value

Modified SOAP Ups Student Awareness of Health Care Costs

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Modification of traditional SOAP presentation to include discussion of value helps medical students