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A quality improvement intervention does not reduce in-hospital mortality for critically ill patients treated in intensive care units

Quality Improvement Process Doesn’t Cut ICU Mortality

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No reduction in in-hospital mortality for critically ill patients from ICUs in Brazil
Use of the word "breakthrough" in the U.S. Food and Drug Administration's expedited approval process could mislead doctors about the new drugs' actual benefits

Doctors Can Be Misled About FDA ‘Breakthrough’ Drug Designation

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Many believe meds supported by stronger evidence than the law requires to achieve designation
A radical proposal has been suggested for eliminating all Veterans Affairs (VA) medical centers and outpatient facilities in the next 20 years

VA Commission on Care: Eliminate VA Medical Centers

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Eight veterans organizations denounce document in letter to Commission Chairwoman
Sinus surgery is more common among firefighters who responded during the first two days of the World Trade Center disaster than those who had less intense or shorter exposures

World Trade Center Exposure, Eosinophilia Predict Sinus Surgery

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Firefighters exposed to dust right after the attack or for long periods later more likely to need surgery
For patients with heart failure with reduced ejection fraction

Sacubitril-Valsartan May Be Cost-Effective Option in HFrEF

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More costly than enalapril but more effective over a lifetime in heart failure with reduced ejection fraction
The U.S. Preventive Services Task Force recommends against screening for chronic obstructive pulmonary disease in asymptomatic adults. These findings form the basis of a recommendation statement published online April 5 in the Journal of the American Medical Association.

USPSTF Recommends Against COPD Screening in Adults

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Grade D recommendation indicates no benefit for people without respiratory symptoms
Regular doses of vitamin D3 may improve cardiac function in heart failure patients

ACC: Vitamin D Found to Improve Cardiac Function in Heart Failure

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Further studies necessary to determine whether this translates to improvements in outcomes
Ixmyelocel-T

ACC: Ixmyelocel-T Beneficial for Heart Failure With Reduced EF

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Significant reduction in primary efficacy end point with ixmyelocel-T therapy

March 2016 Briefing – Pulmonology

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Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for March 2016. This roundup includes the latest...
Young

Even Light-Use Waterpipe Smoking Harms the Lungs

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Findings include biological and clinical abnormalities versus nonsmokers