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Ingrezza (valbenazine)

FDA Approves First Drug for Treatment of Tardive Dyskinesia

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Ingrezza (valbenazine) capsules approved for treatment of adults with tardive dyskinesia
Having a mental health disorder doesn't translate into a higher risk of Alzheimer's disease later in life

Past Psychiatric Disorders Do Not Raise Risk of Alzheimer’s Disease

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But more recent psychiatric symptoms may be part of the disease
Higher serum fasting insulin and insulin resistance predict poorer verbal fluency and a steeper decline in future verbal fluency

Insulin Resistance Predicts Later Cognitive Decline

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Higher serum fasting insulin predicts future decline in verbal fluency
Mindfulness practice during chemotherapy can reduce the blunting of neuroendocrine profiles typically observed in cancer patients

Mindfulness Practice Reduces Cortisol Blunting During Chemo

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Findings in colorectal cancer patients using mindfulness practice at start of chemo sessions
Elderly veterans with post-traumatic stress disorder with dementia have increased odds of being prescribed second-generation antipsychotics compared with those with PTSD alone

SGA Prescribing Higher for Veterans With PTSD/Dementia

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Prescribing of SGAs to veterans with PTSD down, but consistently increased odds for concurrent dementia
Fewer than 1

991 Used Oregon’s Physician-Aided Dying Law 1998 to 2015

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Most patients were white, older, and college-educated
Implementation of the Medicare Access and CHIP Reauthorization Act has made fundamental changes to the government's approach to physician payment

MACRA Changes Government Approach to Doctor Payment

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New approach pays providers based on quality, value, and results delivered, but questions remain
Risk adjustment and reinsurance transfer programs seem to have been effective for increasing revenues at the expense of claims costs

Risk Adjustment, Reinsurance Transfer Offer Financial Benefit

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Revenues exceeded claims costs after implementation of these programs
Cognitively-average elderly adults have greater annual whole-brain cortical volume loss than adults age 80 years and older with episodic memory ability at least as good as that of average middle-age adults (SuperAgers)

‘SuperAgers’ Have Less Whole-Brain Cortical Volume Loss

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Cognitively-average elderly have significantly greater annual percent change compared with SuperAgers
One-fifth of patients who sought a second opinion recently at a single academic medical center had received a different diagnosis from their primary care providers

Second Opinion Yields Different Diagnosis for 1 in 5 Patients

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In study, 21 percent of cases received final diagnoses that were distinctly different than referral diagnoses