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Considerable Uncertainty Exists Regarding Effects of Puberty Blockers

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Two systematic reviews revealed very low-certainty evidence on outcomes for people with gender dysphoria

Incidence, Prevalence of Peripartum Mental Illness Increased for Mothers With MS

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Mothers with MS have higher incidence of any mental illness and of all mental illnesses except suicide

ADHD Incidence Increased Among Adults From 2020 to 2023

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While incidence has remained flat for adolescents since 2018, there has been an uptick for adults since 2020

Medical Use of Cannabis Tied to Higher Prevalence of Cannabis Use Disorder

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Findings seen for younger adults across cannabis use disorder severity levels

Personalized Cognitive Training Via Serious Video Game Aids ADHD Symptoms

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Benefits seen for material organization, working memory, and inhibition

FDA Approves Spravato Nasal Spray for Treatment-Resistant Depression

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Drug is the first and only approved monotherapy for refractory major depressive disorder

Clinical Practice Guidelines Updated for Management of Stroke Rehab

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47 recommendations developed in areas relevant to primary care, including transition to community, motor therapy, mental health

Certain Drug Types Associated With Risk for Dementia

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Antimicrobials, vaccines, anti-inflammatories linked to reduced risk for Alzheimer disease and dementia; antipsychotics and diabetes drugs tied to higher risk

GLP-1 Receptor Agonists Tied to Risks and Benefits Beyond Weight Loss

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Reduced risks seen for neurocognitive, coagulation, cardiometabolic disorders; increased risks seen for GI, arthritic disorders

1999 to 2021 Saw Rise in Methamphetamine-Related Mortality

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This trend may be driven by increases in heroin and synthetic opioids coinvolvement