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HIV-positive transplant recipients and their physicians should be aware of potential interactions between fixed dose combination products used for HIV treatment and immunosuppressant metabolism

Interactions for HIV Drug Combos, Immunosuppressants

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Drug interaction-induced calcineurin inhibitor nephrotoxicity described in renal transplant recipient
Health care professionals should use caution when prescribing the oral antifungal drug fluconazole (Diflucan) during pregnancy because it may raise the risk of miscarriage

FDA: Fluconazole Linked to Increased Miscarriage Risk

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Agency recommends alternatives to fluconazole for mothers-to-be until its review is complete
Certain nutritional supplements may improve the effectiveness of antidepressants

Certain Nutraceuticals May Augment Antidepressant Effects

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Data support adjunctive use of SAMe, methylfolate, omega-3, and vitamin D
Long-term use of statins does not appear to reduce the risk of colorectal cancer

New Research Questions Link Between Statin Use and CRC Risk

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It may be cholesterol levels that are associated with reduced chance of colorectal cancer
An update on Americans' health finds that racial and ethnic disparities persist

U.S. Health Report Card Finds Racial, Ethnic Disparities Persist

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But infant mortality rates, numbers of uninsured are improving, government analysis reveals
The addition of tiotropium to long-acting β2-agonists (LABA) and/or inhaled corticosteroids (ICS) does not reduce chronic obstructive pulmonary disease exacerbations compared to LABA/ICS alone

Triple Therapy No Benefit for COPD Exacerbations

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Findings based long-acting β2-agonists, inhaled corticosteroids + tiotropium
Use of saxagliptin or sitagliptin is not associated with increased risk of hospitalized heart failure compared with other antihyperglycemic agents

Saxagliptin, Sitagliptin Don’t Up Hospitalized Heart Failure

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No increased risk for new users of saxagliptin, sitagliptin versus other antihyperglycemic agents
For children and young adults with high-risk B-acute lymphoblastic leukemia

High-Dose Methotrexate Beneficial in Youth With B-ALL

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Superior to Capizzi methotrexate for high-risk B-acute lymphoblastic leukemia
Infants fed rice-based foods may have significantly higher inorganic arsenic concentrations in their urine than those who never eat rice

Higher Arsenic Levels Detected in Infants Fed Rice-Based Cereals

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Levels in infants who frequently ate baby rice cereal more than three times that of non-rice eaters
Pharmacists can do an effective job helping chronically ill patients manage their blood pressure

Pharmacists Can Manage Some Chronic Conditions Effectively

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New legislation would establish pharmacists as health care providers