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Targeted therapies that do not contain erlotinib can be beneficial for patients with KRAS-mutated advanced non-small-cell lung cancer

Targeted Therapies Beneficial in KRAS-Mutated NSCLC

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Improved progression-free survival for patients treated with therapy not containing erlotinib
Among adults with septic shock

Vasopressin Doesn’t Cut Kidney Failure-Free Days in Septic Shock

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No improvement in kidney failure-free days versus norepinephrine in adults with septic shock
Government spending on compounded drugs has skyrocketed

Spending on Compounded Drugs Skyrocketing

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Number of Medicare beneficiaries getting compounded drugs up 281 percent since 2006
The number of private health insurance claims for Americans addicted to opioids and heroin rose 3

Opioid-Related Insurance Claims Rise 3,000 Percent

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Present crisis disproportionately affecting white, middle-class people in non-urban settings
Opioid users may be misusing and abusing gabapentin

Some Opioid Users May Be Taking Gabapentin Without an Rx

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Findings reveal need for more robust testing
Liraglutide (Victoza) doesn't appear to improve heart function in patients with advanced heart failure

Liraglutide Not Beneficial in Advanced Heart Failure

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No difference in heart function, disease stability or in rates of mortality, rehospitalization
For men with low-risk prostate cancer

Predictors ID’d for Switching to Active Tx in Prostate Cancer

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Ethnicity influences patient decision to pursue active treatment and serial biopsies in active surveillance
For patients with a history of lower gastrointestinal bleeding

Bleeding Risk Up With Aspirin After Lower GI Bleeding

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But continued aspirin use is associated with reduced risk of serious cardiovascular events and death
Biosimilar and reference tumor necrosis factor-α inhibitors appear to be appropriately interchangeable

Biosimilar and Reference TNF-α Inhibitors Comparable

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Pharmacokinetic parameters of both versions within the prespecified equivalence margin
Different approaches to the treatment of opioid-use disorders are addressed in an article published in the July 28 issue of the New England Journal of Medicine.

Physician Reviews Approaches to Treating Opioid-Use Disorders

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Medically-supervised withdrawal is not usually sufficient to induce long-term recovery