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In patients with high-risk relapsed/refractory acute myelogenous leukemia (AML) or untreated AML unfit for intensive chemotherapy

Venetoclax Monotherapy Active in AML With Adverse Features

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Overall response rate 19%; additional 19% have antileukemic activity without meeting IWG criteria
For women undergoing urogynecologic surgery

Polyethylene Glycol 3350 Doesn’t Cut Time to Bowel Movement

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Addition of PEG3350 to docusate sodium cuts use of additional laxatives, increases drug adherence
For patients with Fabry's disease

Tx Response No Different for Migalastat, Placebo in Fabry’s

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Percentage of patients with response at six months doesn't differ with migalastat, placebo treatment
For patients with estrogen receptor-positive metastatic breast cancer

ESR1 Mutations Tied to Worse Survival in Metastatic Breast CA

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ESR1 mutations prevalent in ER-positive metastatic breast cancer and linked to shorter survival
Alitretinoin treatment aids in normalizing expression of barrier genes and proteins in patients with chronic hand eczema

Alitretinoin Cuts Chronic Hand Eczema Severity

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Treatment seems to normalize expression of skin barrier genes, proteins
For patients discharged with acute heart failure (AHF)

CA-125 Strategy Cuts Death, Readmission in Heart Failure

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Effect mainly driven by reduction in rate of rehospitalizations, but not mortality
Intravenous immunoglobulin is increasingly being used for interstitial lung disease

IV Immunoglobulin Use Up in Interstitial Lung Disease

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No studies support use of IVIg in ILD, but increasingly being used off-label for refractory cases
Mitomycin C and 5-flurouracil improve outcomes following Ahmed glaucoma valve implantation

Antifibrotics Up Outcomes After Ahmed Glaucoma Valve Implant

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Adjuvant treatment following AGV implantation improves treatment success, cuts hypertensive phase
A considerable proportion of patients receiving atomoxetine (ATX)

Many Patients Don’t Reach Target Dose of Atomoxetine

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Total days of therapy/year higher for patients who filled at least one 80 mg prescription
At least one San Francisco-area individual died and eight more were treated in the emergency department in late 2015 after taking counterfeit alprazolam (Xanax) tablets that had been cut with fentanyl

Counterfeit Alprazolam Cut With Fentanyl Can Be Fatal

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One person died, eight were sickened when illicit pills circulated in San Francisco