Venetoclax Monotherapy Active in AML With Adverse Features
Overall response rate 19%; additional 19% have antileukemic activity without meeting IWG criteria
Polyethylene Glycol 3350 Doesn’t Cut Time to Bowel Movement
Addition of PEG3350 to docusate sodium cuts use of additional laxatives, increases drug adherence
Tx Response No Different for Migalastat, Placebo in Fabry’s
Percentage of patients with response at six months doesn't differ with migalastat, placebo treatment
ESR1 Mutations Tied to Worse Survival in Metastatic Breast CA
ESR1 mutations prevalent in ER-positive metastatic breast cancer and linked to shorter survival
Alitretinoin Cuts Chronic Hand Eczema Severity
Treatment seems to normalize expression of skin barrier genes, proteins
CA-125 Strategy Cuts Death, Readmission in Heart Failure
Effect mainly driven by reduction in rate of rehospitalizations, but not mortality
IV Immunoglobulin Use Up in Interstitial Lung Disease
No studies support use of IVIg in ILD, but increasingly being used off-label for refractory cases
Antifibrotics Up Outcomes After Ahmed Glaucoma Valve Implant
Adjuvant treatment following AGV implantation improves treatment success, cuts hypertensive phase
Many Patients Don’t Reach Target Dose of Atomoxetine
Total days of therapy/year higher for patients who filled at least one 80 mg prescription
Counterfeit Alprazolam Cut With Fentanyl Can Be Fatal
One person died, eight were sickened when illicit pills circulated in San Francisco