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Depression Risk Lower With GLP-1 Receptor Agonists Versus DPP-4 Inhibitors in Seniors

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Modestly lower risk for depression seen compared with DPP-4i use, but not compared with SGLT-2i use

Epidural Steroid Injections Reviewed for Radicular Pain, Spinal Stenosis

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Some evidence seen for ESIs reducing pain and disability in cervical and lumbar radiculopathies and possibly in lumbar spinal stenosis

Acalabrutinib-Venetoclax Prolongs Survival in Previously Untreated Leukemia

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Progression-free survival significantly lower with fixed-duration acalabrutinib-venetoclax with or without obinutuzumab

Olpasiran Leads to Significant Reduction in Oxidized Phospholipids

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Olpasiran leads to significant and sustained reduction in OxPL on apolipoprotein B

Certain Glucose-Lowering Meds Associated With Lower Risk for COPD Exacerbations

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Lower risk for COPD exacerbations seen with SGLT-2 inhibitors and GLP-1 receptor agonists, but not with DPP-4 inhibitors

Anifrolumab Tied to Less Organ Damage for Patients With Lupus

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Lower likelihood seen for experiencing increase in Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index

Talazoparib + Enzalutamide Tied to Improved Overall Survival in Metastatic Prostate Cancer

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Talazoparib + enzalutamide linked to improved survival for patients with mCRPC unselected for HRR gene alterations

De-Escalating DAPT to Ticagrelor Monotherapy Cuts Bleeding Risk in Acute Coronary Syndrome

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Lower risk for bleeding without increase in ischemic events seen for patients with acute coronary syndrome

FDA Approves First Rapid-Acting Insulin Biosimilar for Patients With Diabetes

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Merilog administered subcutaneously five to 10 minutes before mealtime helps improve glycemic control

Benzoyl Peroxide Formulation Characteristics Explain Variation in Benzene Levels

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Leave-on products linked to lower concentrations of benzene; increased concentrations seen in conditions consistent with hot processing