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Many adolescents with chronic diseases such as asthma and juvenile arthritis have consumed alcohol or smoked marijuana in the last year

Many Teens With Chronic Illnesses Use Alcohol, Marijuana

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Four out of 10 high school students with medical conditions used one or both in past year
For patients with established Chagas' cardiomyopathy

Benznidazole Tx Explored in Chagas’ Cardiomyopathy

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Reduces serum parasite detection but does not reduce cardiac clinical deterioration through 5 years
For patients with an acute coronary syndrome undergoing percutaneous coronary intervention

Bivalirudin Doesn’t Lower Major Cardiovascular Event Rate in ACS

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No decrease in rate of major CV events, net adverse clinical events for patients undergoing PCI

August 2015 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for August 2015. This roundup includes the latest...
In patients with newly diagnosed multiple myeloma

Continuous Therapy Improves Survival in Multiple Myeloma

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Benefit seen in progression-free, overall survival compared with fixed duration of therapy
The risk of osteonecrosis of the jaw is highest in association with intravenous bisphosphonate use

Osteonecrosis of Jaw Risk Highest for IV Bisphosphonate Use

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High risk for zoledronate, denosumab mainly in prevention of skeletal-related events
Intravenous cyclosporine does not improve outcomes versus placebo in patients with anterior ST-segment elevation myocardial infarction who had been referred for primary percutaneous coronary intervention. The findings were published online Aug. 30 in the New England Journal of Medicine to coincide with the annual European Society of Cardiology Congress

Intravenous Cyclosporine Doesn’t Improve STEMI Outcomes

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For patients undergoing PCI, cyclosporine doesn't prevent adverse left ventricular remodeling at 1 year
Use of dipeptidyl peptidase-4 inhibitors in type 2 diabetes is tied to severe joint pain in some patients

FDA Warns of Joint Pain Tied to DPP-4 Inhibitors

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Agency advises users with such symptoms to contact their doctor
For patients taking dabigatran

Lower Risk of Dabigatran-Tied Bleeding With Gastroprotection

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Concomitant use of gastroprotective agents linked to lower risk of gastrointestinal bleeding
Taking antibiotics might increase the risk of developing type 2 diabetes

Antibiotic Use Linked to Higher Type 2 Diabetes Risk

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Researchers don't know if the drugs signal developing disease, or contribute to it