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Gene therapy may benefit children and teens with Wiskott-Aldrich syndrome

Gene Tx May Benefit Children, Teens With Wiskott-Aldrich Sx

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Patient's own blood stem cells are removed to correct the WAS gene, then injected back into the patient
Researchers say they've identified a gene that affects whether children with asthma respond to corticosteroids. The study was published online April 21 in the Journal of Allergy and Clinical Immunology.

VNN1 Gene Potentially Useful Biomarker in Childhood Asthma

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Linked to efficacy of corticosteroids
Oophorectomy is associated with a decrease in mortality in women with breast cancer and a BRCA1 mutation

Oophorectomy Linked to Better Survival in BRCA1 Breast Cancer

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The sooner, the better, researchers found
More than one-quarter of patients with metastatic prostate cancer present with a synchronous second primary malignancy

Second Primaries for Over 25% With Metastatic Prostate Cancer

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28.1 percent have synchronous second primary; mortality up with synchronous lung, stomach cancer
Phenolic-rich maple syrup extract has antimicrobial activity and demonstrates strong synergic interactions with selected antibiotics

Phenolic-Rich Maple Syrup Extract Has Antimicrobial Activity

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PRMSE and catechol efficiently reduce biofilm formation at sub-lethal concentrations
Salpingectomy alone may be a risk management option for women at hereditary risk of ovarian cancer

Review Examines Salpingectomy Alone for Cutting Ovarian CA Risk

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Recent evidence suggests fallopian tube epithelium is origin of most high-grade serous cancers
In a small

High-Dose Oral Insulin Promising for Prevention of T1DM

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Daily capsules trigger protective immune response in high-risk children
Despite evidence that has suggested metformin might have potential in cancer

AACR: Metformin Benefit Lacking in Pancreatic Ductal CA

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Survival not significantly different for pancreatic ductal adenocarcinoma patients
Electronic health records are a valuable source of data that can be mined to help practices with quality improvement performance

EHR Data Mining Helps With Quality Improvement

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Data mining tools, including health maintenance alerts, reports, are available in EHR products
In a discovery that could eventually shed light on some diseases that plague modern society

‘Westernization’ May Drive Disease Via Microbiome

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Finding suggests that 'Western' lifestyle may be driving diseases like asthma, diabetes, obesity