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The first genetic marker to predict response to pembrolizumab (Keytruda) has been identified by researchers

ASCO: MMR Deficiency Predicts Pembrolizumab Response

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Findings may help doctors better choose patients to receive pembrolizumab (Keytruda)
Changes in bacteria populations may be one reason why people who wear contact lenses are more prone to eye infections

Ocular Bacteria Differ for Contact Lens Wearers

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Finding may explain why lens wearers are more prone to infection
Estimated glomerular filtration rate and albumin-to-creatinine ratio improve prediction of cardiovascular risk above traditional risk factors

eGFR, ACR Improve Cardiovascular Risk Prediction

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Addition of eGFR, ACR ups discrimination of CV outcomes above traditional risk factors

May 2015 Briefing – Pathology

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Here are what the editors at HealthDay consider to be the most important developments in Pathology for May 2015. This roundup includes the latest...
Low physician spending is contributing to an overall slowing of health care costs

AMA: Physicians Driving the Slowing of Health Care Costs

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Physicians' spending grew more slowly over 2003 to 2013 than hospital and clinical spending
Patients with HIV should start antiretroviral therapy as soon as they're diagnosed

Greater Benefit for Early Antiretroviral Tx Initiation in HIV

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NIH-funded trial results appear likely to impact global treatment guidelines
Population-based fecal immunochemical testing screening in adults aged 50 to 69 years can reduce colorectal cancer mortality

Population-Based FIT Screening Can Reduce CRC Mortality

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Large cohort study shows significant reduction among screened 50- to 69-year-olds in Taiwan
Among older adults

Specific Trans Fatty Acids Linked With Incident Diabetes

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Correlations differ by specific trans fatty acid and by method of assessment
Copy number variations correlate with phenotypes such as intellectual disability in the general population

Genetic Variants Linked to Educational Attainment

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CNVs linked to lower education attainment in geographically distinct unselected populations
Adhering to a Mediterranean diet may significantly reduce a woman's risk of endometrial cancer

Mediterranean Diet Might Lower Endometrial Cancer Risk

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Women who followed it most closely saw significant reduction in risk