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Caloric restriction improves peripheral insulin sensitivity

TXNIP May Mediate Insulin Sensitivity in Caloric Restriction

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Better peripheral insulin sensitivity tied to reduction in insulin-stimulated thioredoxin-interacting protein
Siblings are the most likely source of pertussis infection in infants

CDC: Source of Infant Pertussis Infection Most Often a Sibling

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This denotes a change from past years, when mothers were most often the source
For patients with primary melanoma

Histologic Regression Tied to Lower Odds of SLN Positivity

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For patients with melanoma, regression linked to lower likelihood of sentinel lymph node positivity
Cerebral palsy is likely due to multiple prenatal factors

Birth Asphyxia Tied to Fewer Than 10% of Cerebral Palsy Cases

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Review suggests that causes other than asphyxia account for most cases in infants born at, near term
In a review article published online Sept. 3 in the New England Journal of Medicine

Suggested Response Provided for In-Flight Medical Emergencies

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Article offers tips for physicians providing emergency in-flight medical care
A needle-exchange program in Washington

D.C. Needle-Exchange Program Curbed HIV Spread

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Effort also saved $44 million in potential disease treatment costs over two years
Average life expectancy among people worldwide has risen by more than six years since 1990

Life Expectancy Increases Seen Worldwide

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Data from 188 countries show average life expectancy is now about 71 years
Patients with asthma may have an increased risk of developing Parkinson's disease

Asthma Linked to Increased Risk of Parkinson’s Disease

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Greater risk of subsequent Parkinson's for patients with asthma with more frequent admissions
An experimental therapy for chronic lymphocytic leukemia that uses a patient's own T cells (an approach known as CTL019) may cure some patients and prolong survival in others

Long-Term Remissions of CLL in First Personalized Cell Tx Trial

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T cells reprogrammed to contain chimeric antigen receptor targeting CD19 protein on B cells
Individuals with type 2 diabetes mellitus may be more prone to developing the neuropathology associated with Alzheimer's disease

Type 2 Diabetes Linked to More Alzheimer’s Neuropathology

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Effect may be driven by tau phosphorylation, researchers say