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2021 to 2022 Saw Decrease in Age-Adjusted Death Rate in U.S.

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Decrease also seen in estimated age-adjusted COVID-19 death rate, from 115.6 to 63.1 per 100,000 persons

Medical Cannabis Effective for Pain Relief in Cancer

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Pain relief better with THC:CBD balanced strains than THC-dominant and CBD-dominant strains

Opioid Exposure Higher Among Adults With Cerebral Palsy Versus Those Without

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Exposures occur for a higher number of days per month and for a longer duration after the initial exposure

Chatbot Generates Quality, Empathetic Responses to Patient Questions

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Chatbot generates higher proportion of responses rated as good or very good quality and empathetic or very empathetic than physicians

E-Health Self-Management Chronic Pain Program Beneficial

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Increase in proportion of patients achieving ≥15 percent reduction in daily morphine equivalent dose, ≥2-point reduction in pain intensity

AAN: Atogepant Efficacious for Preventive Treatment of Migraine

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Findings seen in participants who previously failed two to four classes of oral preventive migraine medications

TKA Complications Increased for Sickle Cell Disease Patients

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Patients with sickle cell disease have longer length of stay, incur greater health care costs, have increased need for step-down health care facilities

Biden to Nominate Head of National Cancer Institute to Run NIH

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A new leader for the U.S. National Institutes of Health could put a fresh focus on efforts to cut cancer death rates

Evidence Limited for Long-Term Benefits of Discectomy for Sciatica

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Benefits for reduction in leg pain and disability declined over time

Fibromyalgia Is Risk Factor for Opioid Use Disorder Exacerbations

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New instrument, the Pain-related OUD Exacerbation Scale, shows validity