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The long-term effectiveness and harms of opioids for chronic pain are unclear

Major Risks of Long-Term Opioid Rx Deemed Dose-Dependent

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In review, serious harms of long-term therapy seemed to depend on opioid dose
Clinicians are increasingly ordering advanced imaging and referring to other physicians for headache but less often providing counseling

Clinicians Increasingly Ordering Imaging for Headaches

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From 1999-2000 to 2009-2010, increases seen in use of CT/MRI, referrals to other physicians
Among youth

High Rates of Missed Diagnoses of Fetal Alcohol Syndrome

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Of youth with fetal alcohol syndrome disorders, 86.5 percent had not been diagnosed, been misdiagnosed
Evidence is insufficient for opioid use in chronic pain

NIH: Insufficient Evidence for Opioid Use in Chronic Pain

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Insufficient evidence for every clinical decision that a provider needs to make about use of opioids
The 10 to 20 minutes of a typical well-child visit isn't enough time to reliably detect a young child's risk of autism

Brief Well-Child Visit Inadequate for ID of Autism Risk

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Typical behaviors often exceed atypical ones and mislead clinicians in brief assessments