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Nonalcoholic steatohepatitis associated changes in liver function affect kidney transporter expression and metformin pharmacokinetics

NASH-Linked Changes Impact Metformin Pharmacokinetics

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Mice study shows alteration in kidney transporter expression, altered metformin pharmacokinetics
Intensive care unit patients who develop delirium have a higher mortality risk

Morbidity, Mortality Up for Patients With Delirium in ICU

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Researchers recommend screening and monitoring for delirium in all critically ill patients
Incorporation of a genetic risk score can improve the accuracy of colorectal cancer risk determination

Model Including CRC Risk Alleles Ups Risk Discrimination

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Model more accurately determines risk of colorectal cancer; defines recommended screening age
For older adults

Hyperhomocysteinemia Linked to Worse Cognitive Status

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Correlation with worse cognitive and functional status, dementia among elderly adults
Nine states have enacted the Interstate Medical Licensure Compact law

Interstate Medical Licensure Compact Formed

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Formation of compact commission triggered by enactment of law in seventh state: Alabama
A patient satisfaction education

Resident Education Intervention Ups Patient Satisfaction

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Improvement in Hospital Consumer Assessment of Healthcare Providers and Systems scores
For patients with gastroesophageal reflux disease

Review: Radioablation Offers No Benefit for GERD Patients

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No improvement in terms of mean time spent with pH less than 4, ability to stop PPIs, HRQoL
Among individuals with type 2 diabetes there is a quadratic association for 24-hour diastolic blood pressure with information processing speed and memory

24-Hour Diastolic BP Linked to Cognitive Performance in T2DM

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Low and high 24-hour diastolic BP tied to poorer information processing speed, memory
Varenicline (Chantix) doesn't increase the risk of suicidal behavior

Some Varenicline Concerns Not Supported by Evidence

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And some concerns may have been overstated, researcher says
Although most Medicare Part D plans cover at least one biologic disease-modifying antirheumatic drug

Most Part D Plans Cover at Least One Biologic DMARD

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In most plans, patients required to pay coinsurance percentage, averaging 29.6 percent of drug costs