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Iressa (gefitinib) has been approved by the U.S. Food and Drug Administration to treat patients with metastatic non-small-cell lung cancer with a specific genetic mutation (epidermal growth factor receptor [EGFR]). A just-approved companion diagnostic test can identify patients who could benefit from this new use.

FDA Approves Iressa for EGFR+ Metastatic Lung Cancer

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New companion diagnostic kit can identify candidates
Three-quarters of American adults favor raising the legal smoking age to 21

CDC: Most Americans in Favor of Raising Legal Smoking Age to 21

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Even 70 percent of smokers support the concept
Trends in hospital deaths among HIV-infected patients show that mortality during the antiretroviral therapy era is often caused by diseases and conditions other than AIDS. The findings were published online June 30 in the Journal of Hospital Medicine.

Non-AIDS In-Hospital Deaths Up in HIV-Infected Patients

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Non-AIDS infections and cardiovascular disease are common causes of mortality in the ART era
The American Society of Clinical Oncology has endorsed postoperative radiation therapy guidelines for endometrial cancer

ASCO Endorses ASTRO Guidelines for Endometrial Cancer

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Qualifications to guidelines include stronger statements in favor of chemotherapy in some cases
The benefit of extended anticoagulation after pulmonary embolism dissipates after cessation of active therapy

Benefits of Extended Anticoagulation May Not Last

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New study suggests that oral anticoagulant meds may be needed for the very long term
People living in 94 counties spread across the lower Mississippi Delta region

Pockets of U.S. Have Excessive Colorectal Cancer Mortality

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Areas include parts of the Mississippi Delta, Appalachia, and eastern Virginia
More U.S. physicians are sparing their low-risk prostate cancer patients from prostatectomy

Surveillance Becoming More Common for Prostate Cancer

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Many men with low-risk disease being spared prostatectomy, radiation, androgen deprivation tx
Certain genetic mutations may be correlated with response to therapy and prognosis in aplastic anemia

Genetic Mutations May Impact Outcomes in Aplastic Anemia

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Genetic evaluation may help predict prognosis in aplastic anemia
For many cancers

Mortality Rates Declining for Many Cancers

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Rates predicted to meet Healthy People 2020 targets for breast, lung, prostate cancers
Increased numbers of small cancers and precancerous lesions are found in geographical areas where more mammograms take place; however

Regular Mammograms May Lead to Widespread Overdiagnosis

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No significant difference in breast cancer deaths for counties with higher screening, detection rates