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Glucarpidase Improves Outcomes in Patients With Methotrexate-Induced Kidney Toxicity

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Glucarpidase associated with 2.70-fold increased odds of kidney recovery in methotrexate-acute kidney injury

TACE + Lenvatinib, Pembrolizumab Tied to Improved Survival in Unresectable Liver Cancer

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Clinically meaningful improvement seen in progression-free survival for transarterial chemoembolization plus lenvatinib and pembrolizumab

Cancer Mortality Continued to Decline Through 2022

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However, increase seen in incidence in women, especially for middle-aged and younger women

Adjuvant Trastuzumab Emtansine Improves Overall Survival in HER2+ Breast Cancer

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T-DM1 sustained the improvement in invasive disease-free survival over trastuzumab in HER2-positive early breast cancer

FDA Proposes Nicotine Limits on Combustible Tobacco Products

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Proposal suggests lowering nicotine levels in cigarettes and other tobacco products to minimally or nonaddictive levels

Machine Learning Model Accurately Predicts Survival in Merkel Cell Cancer

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Tool demonstrated generalizability through high predictive performance in international clinical cohort

Hormone Therapy Not Associated With Glioma Risk in Women

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Similar findings with no significant association seen when accounting for hormone therapy status and duration of use

Shifts in Trends Noted for Trachea, Bronchus, Lung Cancer Mortality

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Tobacco-associated trachea, bronchus, and lung cancer mortality decreasing overall, while pollution-associated mortality increasing

FDA Will No Longer Allow Use of Red Dye No. 3 in Food, Drugs

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Agency revokes previous authorization for color additive to be used in food and ingested drugs

Differences Exist in Precision Oncology Drug Eligibility Among Patient Ancestral Groups

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Patients of African ancestry had the lowest precision oncology drug-based clinical actionability from 2019 onward