Glucarpidase Improves Outcomes in Patients With Methotrexate-Induced Kidney Toxicity
Glucarpidase associated with 2.70-fold increased odds of kidney recovery in methotrexate-acute kidney injury
TACE + Lenvatinib, Pembrolizumab Tied to Improved Survival in Unresectable Liver Cancer
Clinically meaningful improvement seen in progression-free survival for transarterial chemoembolization plus lenvatinib and pembrolizumab
Cancer Mortality Continued to Decline Through 2022
However, increase seen in incidence in women, especially for middle-aged and younger women
Adjuvant Trastuzumab Emtansine Improves Overall Survival in HER2+ Breast Cancer
T-DM1 sustained the improvement in invasive disease-free survival over trastuzumab in HER2-positive early breast cancer
FDA Proposes Nicotine Limits on Combustible Tobacco Products
Proposal suggests lowering nicotine levels in cigarettes and other tobacco products to minimally or nonaddictive levels
Machine Learning Model Accurately Predicts Survival in Merkel Cell Cancer
Tool demonstrated generalizability through high predictive performance in international clinical cohort
Hormone Therapy Not Associated With Glioma Risk in Women
Similar findings with no significant association seen when accounting for hormone therapy status and duration of use
Shifts in Trends Noted for Trachea, Bronchus, Lung Cancer Mortality
Tobacco-associated trachea, bronchus, and lung cancer mortality decreasing overall, while pollution-associated mortality increasing
FDA Will No Longer Allow Use of Red Dye No. 3 in Food, Drugs
Agency revokes previous authorization for color additive to be used in food and ingested drugs
Differences Exist in Precision Oncology Drug Eligibility Among Patient Ancestral Groups
Patients of African ancestry had the lowest precision oncology drug-based clinical actionability from 2019 onward