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Praluent (alirocumab) injection has been approved by the U.S. Food and Drug Administration for use in addition to diet and maximally tolerated statin therapy in adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease

FDA Approves Praluent for Certain Cases of High Cholesterol

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First in a new class of injectable cholesterol-lowering medications
About 10 percent of cases where a drug does serious harm are not reported to the U.S. Food and Drug Administration within the required 15-day period

Delays Noted in the Reporting of Serious Patient Harms to FDA

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Analysis found roughly 10 percent of cases were filed after 15-day deadline passed
A small trial shows a dose-dependent reduction in peripheral neuropathic pain in patients with diabetes

Cannabis Alleviates Peripheral Neuropathic Pain in Diabetes

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Dose-dependent reduction in pain with inhaled cannabis in trial of 16 patients
As a result of the increasing popularity of high-deductible health care plans

Expansion of High-Deductible Plans to Impact Physician Care

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Physicians must be able to balance provision of good clinical care with ability to limit costs
Roux-en-Y gastric bypass is associated with attenuated markers of oxidative stress in subcutaneous adipose tissue

Improved Metabolic Profile After Roux-en-Y Gastric Bypass

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A 3.5-fold AMPK activity increase and 50 percent drop in oxidative stress three months after surgery
The accuracy of blood glucose meters in the low glycemic range is questionable

Blood Glucose Meter Accuracy Unclear at Low Glycemic Range

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Raises questions regarding safety for measuring blood glucose, and when BGMs are used in trials
Taking two 12-week courses of alefacept -- a drug already approved to treat psoriasis -- may help people with newly diagnosed type 1 diabetes mellitus preserve pancreatic β-cell function

Psoriasis Med May Help Preserve Pancreas Function in Type 1 DM

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Used early after diagnosis, medication appears to have long-lasting effects
Testosterone therapy doesn't appear to increase the risk of venous thromboembolism

No Link Found Between Testosterone Therapy and VTE

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Finding based on data from more than 30,000 American men, 40 and older
Use of glitazones may help protect against Parkinson's disease

Glitazone Usage Tied to Lower Risk for Parkinson’s Disease

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Lower risk of Parkinson's seen only with current use of glitazone
Two trajectories of growth correlate with development of type 2 diabetes

Two Trajectories of Childhood Growth for Type 2 Diabetes

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Both start with low weight and BMI at birth; rapid BMI increase in childhood in one pathway