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Praxbind (idarucizumab) has been approved for use in patients who are taking the anticoagulant Pradaxa (dabigatran) when there is an urgent need to reverse Pradaxa's anticoagulant effects

FDA Approves Praxbind to Reverse Pradaxa’s Effect

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Praxbind cleared for emergency use with Pradaxa when bleeding can't be controlled
A ratio evaluating the expression of two molecular markers may assist in the rapid diagnosis of community-acquired pneumonia on ICU admission

Gene Expression Ratio May Aid Rapid Pneumonia Diagnosis

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The FAIM3:PLAC8 ratio may help with community-acquired pneumonia diagnosis on ICU admission
In the Action to Control Cardiovascular Risk in Diabetes trial

Insulin Dose Doesn’t Up Mortality in ACCORD Trial

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No significant association remained after adjustment for baseline covariates
The application of failure mode and effective analysis correlates with increased awareness of medical errors in the pediatric intensive care unit

‘Failure Mode and Effective Analysis’ Ups Error Awareness

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Increase in reported errors, reduction in severity of errors with application of FMEA in PICU
For patients with poor-prognosis cancer

Time-Limited Strategies Feasible for ICU Critical Cancer Care

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For patients with poor-prognosis solid tumors, trial duration of one to four ICU days may be sufficient
As many as half of postsurgical infections and more than a quarter of infections after chemotherapy are caused by organisms already resistant to standard antibiotics

Rising Threat of Antibiotic Resistance in Surgery, Chemo

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10 percent rise in antibiotic resistance would lead to 2,100 more deaths, 40,000 more infections yearly
For extremely premature infants

Budesonide May Be Beneficial in Extremely Preterm Infants

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Reduced incidence of bronchopulmonary dysplasia but may be linked to increased mortality
Intrinsic qualities of safety-net hospitals

Safety-Net Hospitals Have Higher Costs, Worse Outcomes

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Found to have higher mortality, readmission, surgical costs after controlling for patient factors
Exposure to high-strain jobs is associated with an increased risk of stroke

Stroke Risk Higher for People With High-Strain Jobs

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Findings more pronounced for ischemic stroke, significant only in women
Enterovirus D68 seems to be a more virulent pulmonary pathogen in children than rhinovirus or non-EV-D68 enterovirus

Enterovirus D68 Doesn’t Raise Mortality Risk in Children

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But it increases the likelihood of respiratory distress compared with rhinovirus, non-EV-D68