Therapeutic Value of Drugs Lower for Supplemental Versus First Indications
For first three approved indications, second and third indication approvals less likely to have high value rating
Report Estimates Costs of Birth Defect-Associated Hospitalizations
Total estimated cost of birth defect-associated hospitalizations was $22.2 billion in the United States in 2019
Variation in Total Cholesterol, Triglycerides Linked to Alzheimer Disease Risk
Those in highest quintile of total cholesterol, triglycerides had increased risk for AD and Alzheimer-related dementias
Statement Outlines Inequities in Cardio-Oncology Care, Research
Women have higher rates of certain cardiotoxicities; risk for cardiotoxicity and cardiovascular death with anticancer therapy increased for Black patients
Heavy Alcohol Intake Linked to Obesity, Type 2 Diabetes
Genetic evidence does not support protective effects of modest alcohol consumption on obesity traits, T2D
Metabolic Surgery Cuts Cardiovascular Events for Obesity, Sleep Apnea
Risk reduced by more than one-third versus matched individuals without surgery
Vitamin D Supplementation May Cut Risk of Major Cardiovascular Events
Reduction was not significant overall, but was significant among those taking cardiovascular drugs at baseline
A-Fib Linked to Increased Odds of MCI, Dementia in Women
Women with atrial fibrillation and normal baseline cognition had higher risk of disease progression from normal to MCI, MCI to dementia
Overweight BMI Does Not Necessarily Mean Higher Mortality Risk
21 to 108 percent increased mortality risk seen for those with BMI ≥30 kg/m²; no increase seen with BMI of 22.5 to 34.9 kg/m² for older adults
FDA Approves First Blood Test to Predict Preeclampsia in Pregnant Women
Test is meant for women in the 23rd to 35th weeks of pregnancy
