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Lorundrostat Effective for Lowering BP in Uncontrolled Hypertension

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Changes in office systolic BP of −14.1, −13.2, −6.9, and −4.1 mm Hg seen with 100, 50, 12.5 mg once daily of lorundrostat and placebo

Exercise Stress Tests Can Also Predict Noncardiovascular Deaths

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Low functional aerobic capacity, abnormal heart rate recovery, and low chronotropic index tied to noncardiovascular death

Hypertension, Statin Use Increased for Individuals Using TAF for PrEP

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Incident hypertension, statin use higher with tenofovir alafenamide fumarate compared with tenofovir disoproxil fumarate

Risk for Dementia Reduced in Association With Antihypertensive Use

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Individual patient data meta-analysis shows increased risk for dementia for those with untreated hypertension

Whites Have Greatest Magnitude of Association of Socioeconomic Status With LE8

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Magnitude of positive association for four socioeconomic status categories with LE8 was greater for non-Hispanic Whites than minority groups

Seasonal Difference Observed in Systolic Blood Pressure

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Seasonal variation of 1.4 mm Hg tied to nearly 5 percent variation in blood pressure control

Hypertension While Lying Down Tied to Worse Cardiovascular Disease Outcomes

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Findings seen regardless of whether hypertension persists in seated position

Cardiac Arrest Survival Lower at EMS Agencies Serving Minority Populations

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Difference not explained by response times, rates of EMS termination of resuscitation, or rates of initiating CPR or automated external defibrillator

Hypoattenuation Thickening on CT Prognostic After Left Atrial Appendage Occlusion

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High-grade hypoattenuation thickening on follow-up CT after left atrial appendage occlusion associated with higher stroke risk

Lead Exposure Poses Considerable Global Health, Economic Burden

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>90 percent of total global IQ loss and cardiovascular disease deaths occurred in low-, middle-income countries