Quality of evidence often insufficient for providing unequivocal best practices
MONDAY, Aug. 29, 2016 (HealthDay News) — Best practices have been developed for managing children with celiac disease (CD), according to a special article published online Aug. 26 in Pediatrics.
John Snyder, M.D., from the Children’s National Health Systems in Washington, D.C., and colleagues performed a critical review of the literature in six categories associated with CD to develop a set of best practices. The categories included bone health, hematologic issues, endocrine problems, liver disease, issues related to nutrition, and testing. Standardized criteria were used for assessing the quality of the data, grade of evidence, and the strength of the conclusions. One hundred seventy-two publications were included.
The researchers found that the quality of evidence was frequently inadequate for providing unequivocal best practices. Based on the available data and clinical experience of the panel, the researchers created a practical framework for management of CD in children. Consensus, measured by the outcome of anonymous voting, was reached by the panel for 24 of the 25 questions.
“We hope that these best practices may be useful to the pediatric gastroenterology and larger general pediatric communities,” the authors write.
One author disclosed financial ties to the pharmaceutical and nutrition industries.
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