Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for October 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Calquence Approved for Mantle Cell Lymphoma
TUESDAY, Oct. 31, 2017 (HealthDay News) — Calquence (acalabrutinib) has been approved by the U.S. Food and Drug Administration to treat adults with mantle cell lymphoma.
Internists Key to Identifying Need for Genetic Counseling for Cancer
TUESDAY, Oct. 31, 2017 (HealthDay News) — Internists play an important role in identifying which patients may be predisposed to cancer and could benefit from genetic counseling, according to an opinion piece published online Oct. 30 in the Annals of Internal Medicine.
Ultrasonography Not Necessary for Evaluation of Hypothyroidism
TUESDAY, Oct. 31, 2017 (HealthDay News) — Imaging studies, including thyroid ultrasonography, are not required for the evaluation of hypothyroidism, and their risks include treatment of incidentally discovered nodules, patient and physician anxiety, and significant cost, according to a clinical review article published online Oct. 30 in JAMA Internal Medicine.
Depressive Symptoms Increase During Internship Year
TUESDAY, Oct. 31, 2017 (HealthDay News) — Depressive symptoms increase during the internship year for training physicians, with a greater increase among women, according to a study published online Oct. 30 in JAMA Internal Medicine.
Computed Tomography Features Vary Based on BRCA Status
THURSDAY, Oct. 31, 2017 (HealthDay News) — Qualitative computed tomography (CT) features differ between patients with BRCA-mutant high-grade serous ovarian cancer (HGSOC) and patients with BRCA wild-type HGSOC, according to a study published in the November issue of Radiology.
Multimodal Surveillance Regimen May Not Benefit BRCA Carriers
MONDAY, Oct. 30, 2017 (HealthDay News) — Automated breast ultrasonography may not be of added value to yearly full-field digital (FFD) mammography and dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging surveillance of carriers of the BRCA mutation, according to a study published in the November issue of Radiology.
More Than One in Five U.S. Working Adults Uses Tobacco
MONDAY, Oct. 30, 2017 (HealthDay News) — Overall, 22.1 percent of working U.S. adults currently use any form of tobacco, according to a study published online Oct. 26 in Morbidity and Mortality Weekly Report.
Elastography and Color Doppler Improve Breast Ultrasound
MONDAY, Oct. 30, 2017 (HealthDay News) — The combination of elastography and color Doppler ultrasonography (US) with B-mode US in women with dense breasts can increase the positive predictive value of screening and reduce the number of false-positives, according to a study published in the November issue of Radiology.
Flow Cytometry Assesses Minimal Residual Disease in Myeloma
MONDAY, Oct. 30, 2017 (HealthDay News) — Data on methods used for assessing minimal residual disease (MRD) in multiple myeloma (MM) are presented in a report published online Oct. 23 in the International Journal of Laboratory Hematology.
Treatment for Stage I NSCLC Patients Up From 2000 to 2010
FRIDAY, Oct. 27, 2017 (HealthDay News) — For patients with stage I non-small-cell lung cancer (NSCLC), the odds of receiving radiation therapy (RT) or surgery increased from 2000 to 2010, with improved survival during the same period, according to a study published online Oct. 26 in the Annals of Thoracic Surgery.
Multidisciplinary Model Cuts Treatment Delay in Head, Neck CA
FRIDAY, Oct. 27, 2017 (HealthDay News) — For patients with head and neck cancer, a multidisciplinary head and neck clinic model is associated with reduced treatment delay, according to a study published online Oct. 26 in JAMA Otolaryngology — Head & Neck Surgery.
Gastric Cancer Incidence Down, Survival Up
FRIDAY, Oct. 27, 2017 (HealthDay News) — Since 1984, there has been decreased incidence and increased survival rates for gastric cancer (GC), but long-term survival remains low, according to a study published online Oct. 19 in the Journal of Gastroenterology and Hepatology.
70-Gene Signature Impacts Treatment Decisions in Breast CA
FRIDAY, Oct. 27, 2017 (HealthDay News) — The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a study published online Oct. 26 in JAMA Oncology.
HER3 Linked to Improved Survival With Panitumumab
THURSDAY, Oct. 26, 2017 (HealthDay News) — Higher HER3 expression is associated with improved survival with the addition of panitumumab treatment for patients with RAS wild-type (wt) advanced colorectal cancer, according to a study published online Oct. 26 in JAMA Oncology.
Better Outcomes With Transoroal Robotic Surgery Alone in OPSCC
THURSDAY, Oct. 26, 2017 (HealthDay News) — For patients with oropharyngeal squamous cell carcinoma (OPSCC), transoral robotic surgery (TORS) alone is associated with improved outcomes versus TORS followed by adjuvant treatment, according to a study published online Oct. 26 in JAMA Otolaryngology — Head & Neck Surgery.
Cataract Surgery Associated With Reduced Mortality in Women
THURSDAY, Oct. 26, 2017 (HealthDay News) — For older women with cataract, cataract surgery is associated with lower all-cause and cause-specific mortality, according to a study published online Oct. 26 in JAMA Ophthalmology.
Demand for Fertility Preservation Increasing for Women
THURSDAY, Oct. 26, 2017 (HealthDay News) — The demand for fertility preservation is increasing, and methods to address it include oocyte cryopreservation and ovarian-tissue cryopreservation, according to a review article published online Oct. 25 in the New England Journal of Medicine.
Gifts From Pharma Companies Influence Prescribing Behavior
THURSDAY, Oct. 26, 2017 (HealthDay News) — Receipt of gifts from pharmaceutical companies is associated with more prescriptions per patient and more costly prescriptions, according to a study published online Oct. 25 in PLOS One.
Detectable Levels of Roundup Ingredient Rising in Older Adults
WEDNESDAY, Oct. 25, 2017 (HealthDay News) — Detectable levels of glyphosate, the primary ingredient in the herbicide Roundup, have significantly increased in older adults over time, according to a research letter published online Oct. 24 in the Journal of the American Medical Association.
Robotic Radical Nephrectomy Becoming More Common
WEDNESDAY, Oct. 25, 2017 (HealthDay News) — From 2003 to 2015 there was an increase in use of robotic-assisted radical nephrectomy, according to a study published online Oct. 24 in the Journal of the American Medical Association. In a separate study, researchers found that robotic-assisted laparoscopic surgery for resection of rectal adenocarcinoma does not significantly reduce the risk of conversion to open surgery when compared with conventional laparoscopy.
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Most Patients Satisfied With Relationship With Physician
WEDNESDAY, Oct. 25, 2017 (HealthDay News) — Results of the Physicians Foundation 2017 Patient Survey show that most patients are satisfied with their overall relationship with their physician, according to an article published by the American Academy of Family Physicians.
Mechanism ID’d for Chemo-Related Peripheral Neuropathy
WEDNESDAY, Oct. 25, 2017 (HealthDay News) — Researchers may have uncovered the mechanism for chemotherapy-induced peripheral neuropathy (CIPN) related to paclitaxel, according to a study published online Oct. 11 in Neuron.
DEA Taking Back Unwanted Prescription Drugs on Oct. 28
TUESDAY, Oct. 24, 2017 (HealthDay News) — The public is being given its 14th opportunity to safely dispose of pills and patches at collection points operated by the U.S. Drug Enforcement Agency (DEA) and its partners.
Swedish Massage May Reduce Cancer-Related Fatigue
TUESDAY, Oct. 24, 2017 (HealthDay News) — Swedish massage therapy (SMT) is associated with clinically significant relief from cancer-related fatigue (CRF) in breast cancer survivors, according to a study published online Oct. 17 in Cancer.
Ramucirumab Shows Promise in Care of Advanced Gastric Cancer
TUESDAY, Oct. 24, 2017 (HealthDay News) — Ramucirumab appears to be safe and effective for the treatment of advanced gastric cancer, according to a study published online Sept. 29 in the Journal of Gastroenterology and Hepatology.
Design Thinking Enables Med Students to Solve Challenges
MONDAY, Oct. 23, 2017 (HealthDay News) — A joint effort between students at Warren Alpert Medical School of Brown University and Rhode Island School of Design (RISD) is training future physicians in design thinking to help identify and repair health system issues that contribute to physician burnout, according to an article by the American Medical Association.
Leukemia Patients Who Survive Severe GVHD Often Fare Worse
MONDAY, Oct. 23, 2017 (HealthDay News) — After hematopoietic stem cell transplantation (HSCT) for acute leukemia, patients who survive severe acute graft-versus-host disease (aGVHD) have a higher risk of developing extensive chronic GVHD (cGVHD) and a higher rate of non-relapse mortality compared with those who did not develop severe aGVHD, according to a study published online Oct. 13 in the Journal of Internal Medicine.
2003 to 2014 Saw Drop in Urinary Arsenic in Public Water Users
MONDAY, Oct. 23, 2017 (HealthDay News) — From 2003 to 2014, urinary arsenic decreased among users of public water systems but not among private well users, according to a study published online Oct. 22 in the The Lancet Public Health.
Limited Evidence of Benefit for Medical Cannabinoids in Children
MONDAY, Oct. 23, 2017 (HealthDay News) — The strongest evidence for benefit of cannabinoids in children is for chemotherapy-induced nausea and vomiting, with more research needed to assess its role as a medical treatment, according to a review published online Oct. 23 in Pediatrics.
Clinician Job Satisfaction Linked to Improved Burnout Scores
FRIDAY, Oct. 20, 2017 (HealthDay News) — Clinicians’ job satisfaction is associated with improved burnout scores and reduced intention to leave their practices, according to a study published in the October issue of Health Affairs.
For Hepatitis B Patients, Aspirin Tied to Lower Risk of HCC
FRIDAY, Oct. 20, 2017 (HealthDay News) — Aspirin therapy is associated with a reduced risk of hepatitis B virus-related hepatocellular carcinoma (HCC), according to a study scheduled for presentation at The Liver Meeting, held by the American Association for the Study of Liver Diseases from Oct. 20 to 24 in Washington, D.C.
Oncogenic Oral HPV DNA Detected in 3.5 Percent of Adults
FRIDAY, Oct. 20, 2017 (HealthDay News) — Men have a higher prevalence of oncogenic oral human papillomavirus (HPV) than women, and prevalence increases with the number of lifetime oral sexual partners and tobacco use, according to a study published online Oct. 19 in the Annals of Oncology.
In Norway, Risk of SCC After Organ Transplant Has Fallen
FRIDAY, Oct. 20, 2017 (HealthDay News) — For organ recipients in Norway, the risk of skin cancer, particularly squamous cell carcinoma (SCC), has decreased since the mid-1980s, according to a study published online Oct. 18 in JAMA Dermatology.
Melanoma Staging Undergoes Evidence-Based Revision
FRIDAY, Oct. 20, 2017 (HealthDay News) — The American Joint Committee on Cancer (AJCC) melanoma staging system has been revised, according to a report published online Oct. 13 in CA: A Cancer Journal for Clinicians.
Cryotherapy May Prevent Chemo-Induced Neuropathy
FRIDAY, Oct. 20, 2017 (HealthDay News) — Cryotherapy may be useful for preventing symptoms of chemotherapy-induced peripheral neuropathy (CIPN), according to a study published online Oct. 12 in the Journal of the National Cancer Institute.
Gene Tx Approved for Certain Types of B-Cell Lymphoma
THURSDAY, Oct. 19, 2017 (HealthDay News) –Yescarta (axicabtagene ciloleucel) has been approved by the U.S. Food and Drug Administration for individuals with certain types of large B-cell lymphoma who have not responded to or who have relapsed after at least two other kinds of treatment.
Uninsurance Down by One-Third for Cancer Diagnoses in 2014
THURSDAY, Oct. 19, 2017 (HealthDay News) — In the first year of the Affordable Care Act (ACA), there was a relative decrease of one-third in uninsurance among adults with new cancer diagnoses, according to a research letter published online Oct. 19 in JAMA Oncology.
Conditions Tied to Clinician Dissatisfaction Are Modifiable
THURSDAY, Oct. 19, 2017 (HealthDay News) — Modifiable conditions, like chaos, incohesiveness, and lack of communication, contribute to unsatisfying workplaces for clinicians, according to a study published in the October issue of Health Affairs.
Gene Expression Assay Classifies Diffuse Large B-Cell Lymphoma
THURSDAY, Oct. 19, 2017 (HealthDay News) — A novel gene expression profiling diffuse large B-cell lymphoma (DLBCL) classifier, which evaluates the expression of 21 markers, is effective for classifying samples, according to a study published online Oct. 17 in the Journal of Molecular Diagnostics.
Key Stakeholders Discuss How to Make EHRs More Usable
THURSDAY, Oct. 19, 2017 (HealthDay News) — Key stakeholders and physicians discussed electronic health record (EHR) usability and optimization in the American Medical Association Running Your Practice Community.
Oral Antibiotics Cut Risk of SSI in Colorectal CA Resection
WEDNESDAY, Oct. 18, 2017 (HealthDay News) — For patients undergoing left colon and rectal cancer resections, the addition of oral antibiotics to mechanical bowel preparation (MBP) is associated with a reduced rate of surgical site infections (SSIs), according to a study published online Oct. 18 in JAMA Surgery.
Sharing Passwords Is Widespread Among Medical Staff
WEDNESDAY, Oct. 18, 2017 (HealthDay News) — Sharing of passwords to access electronic medical records is common among medical staff members, according to a study published in the July issue of Healthcare Informatics Research.
Men Now Comprise ~10 Percent of RN Workforce
WEDNESDAY, Oct. 18, 2017 (HealthDay News) — The increasing participation of men in registered nursing can be attributed to multiple factors, including increasing educational attainment, rising labor demand in health care, and liberalizing gender role attitudes, according to a working paper published by the Washington Center for Equitable Growth.
Visceral Adipose Tissue Index IDs Risk of HCC in Cirrhosis
WEDNESDAY, Oct. 18, 2017 (HealthDay News) — For male patients with cirrhosis, visceral adipose tissue index (VATI) is an independent risk factor for hepatocellular carcinoma (HCC), according to a study published online Oct. 10 in Hepatology.
Overall Survival Up for Melanoma Brain Metastases
WEDNESDAY, Oct. 18, 2017 (HealthDay News) — Overall survival (OS) for patients with melanoma brain metastases (MBM) has improved significantly since 2000, according to a study published online Oct. 12 in Cancer.
Machine Learning Model Predicts Risk of Upgrade to Breast CA
TUESDAY, Oct. 17, 2017 (HealthDay News) — A machine learning model can predict the risk of upgrade of high-risk breast lesions (HRLs) to cancer, according to a study published online Oct. 17 in Radiology.
Mortality Up for Male Recipients of Blood From Ever-Pregnant
TUESDAY, Oct. 17, 2017 (HealthDay News) — For males, receipt of a red blood cell transfusion from an ever-pregnant female is associated with increased rate of all-cause mortality compared with a male donor, according to a study published online Oct. 17 in the Journal of the American Medical Association.
Prevalence of Oral HPV Infection Higher for U.S. Men
TUESDAY, Oct. 17, 2017 (HealthDay News) — Oral human papillomavirus (HPV) infection and high-risk oral HPV infection are more common among men than women, according to a study published online Oct. 16 in the Annals of Internal Medicine.
Gastric Acid Suppression May Promote Liver Injury
TUESDAY, Oct. 17, 2017 (HealthDay News) — Based on data from mouse models and humans, a decrease in gastric acid secretion due to use of gastric acid suppressive medications seems to promote overgrowth of intestinal Enterococcus, which promotes liver disease, according to a study published online Oct. 10 in Nature Communications.
‘Liquid Biopsy’ Shows Promise for Hepatocellular Carcinoma
TUESDAY, Oct. 17, 2017 (HealthDay News) — ‘Liquid biopsy’ technology holds promise for diagnosing, monitoring, and predicting prognosis in patients with hepatocellular carcinoma (HCC), according to a study published online Oct. 9 in Nature Materials.
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Female Physicians May Be Especially at Risk of Burnout
TUESDAY, Oct. 17, 2017 (HealthDay News) — Female physicians are more burned out than their male colleagues, but there are steps they can take to reduce the stress associated with burnout, according to a blog post published in Medical Economics.
Most Female Physicians Have Faced Sexist Patient Comments
MONDAY, Oct. 16, 2017 (HealthDay News) — Most female physicians have been sexually harassed by patients at some point in their careers, according to a blog post published in Medical Economics.
Online Ratings Not Aligned With Objective Quality Measures
MONDAY, Oct. 16, 2017 (HealthDay News) — Online consumer ratings of specialist physicians do not predict objective measures of quality of care or peer assessment of clinical performance, according to a study published online Sept. 8 in the Journal of the American Medical Informatics Association.
Increase in Rate of Breast Reconstruction for Mastectomy
MONDAY, Oct. 16, 2017 (HealthDay News) — From 2009 to 2014 there was an increase in the population rate of breast reconstruction for mastectomy, which was seen for all age groups, according to a report published in an October Statistical Brief of the Agency for Healthcare Research and Quality.
Model Predicts Cost-Effectiveness for Anal Lesion Treatment
MONDAY, Oct. 16, 2017 (HealthDay News) — Cost-effective management of precancerous anal intraepithelial lesions in HIV-positive men who have sex with men (MSM) varies by age, according to a study published online Sept. 26 in Cancer.
Serious Suffering Affects Almost Half of Those Who Die Yearly
FRIDAY, Oct. 13, 2017 (HealthDay News) — In 2015, more than 25.5 million people who died worldwide experienced serious health-related suffering (SHS), and the vast majority lacked access to palliative care and pain relief, according to a report published online Oct. 12 in The Lancet.
Pre-Retirement Morbidity Higher in Later Birth Cohorts
FRIDAY, Oct. 13, 2017 (HealthDay News) — Americans who must work longer to reach Social Security retirement age have worse measures of health in the years leading up to retirement, according to a study published in the October issue of Health Affairs.
Aqueous Humor Can Serve as Surrogate Tumor Biopsy
FRIDAY, Oct. 13, 2017 (HealthDay News) — A novel method will allow for analyses of tumor-derived DNA in eyes with retinoblastoma (Rb) undergoing salvage therapy that have not been enucleated, according to a study published online Oct. 12 in JAMA Ophthalmology.
Quality Issues for Both Paper-, Electronic-Based Health Records
FRIDAY, Oct. 13, 2017 (HealthDay News) — Both paper-based and electronic health records (EHRs) have shortcomings in terms of quality of content, process, and structure, with poor quality of nursing documentation seen for both methods, according to a study published online Oct. 5 in the Journal of Clinical Nursing.
U.S. Filipinos Have Higher Thyroid Cancer Mortality
FRIDAY, Oct. 13, 2017 (HealthDay News) — Filipinos die of thyroid cancer at higher rates than non-Filipino Asian (NFA) and non-Hispanic white (NHW) individuals of similar ages, according to a study published online Sept. 7 in Cancer.
Across U.S., Wide Variation Seen in Thyroidectomy Rates
THURSDAY, Oct. 12, 2017 (HealthDay News) — There is wide variation in thyroidectomy rates among Medicare beneficiaries nationally, suggesting widely divergent local practice patterns for the management of thyroid nodules and cancer, according to a study published online Oct. 12 in JAMA Otolaryngology — Head & Neck Surgery.
Genetic Variant Tied to Prostate Cancer Outcomes
THURSDAY, Oct. 12, 2017 (HealthDay News) — The HSD3B1 (1245C) allele is associated with more rapid development of metastases in men with biochemically recurrent prostate cancer, and it predicts response to nonsteroidal CYP17A1 inhibition, according to two studies published online Oct. 12 in JAMA Oncology.
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Court Considering Fate of Noneconomic Damages Cap
THURSDAY, Oct. 12, 2017 (HealthDay News) — The Wisconsin Supreme Court is considering whether it will hear a case that will determine the fate of the state’s $750,000 cap on noneconomic damages, according to an article published by the American Medical Association (AMA).
New System Streamlines CME Credit Approval Process
THURSDAY, Oct. 12, 2017 (HealthDay News) — The American Academy of Family Physicians (AAFP) and the American Board of Family Medicine (ABFM) have launched a new performance improvement activity credit reporting process called the AAFP Credit System, according to an article published by the AAFP.
Neurotoxicity Characterized After Infusion of CD19 CAR-T Cells
THURSDAY, Oct. 12, 2017 (HealthDay News) — Patients with severe neurotoxicity after infusion of CD19-targeted chimeric antigen receptor-modified T (CAR-T) cells have evidence of endothelial activation, according to a study published online Oct. 12 in Cancer Discovery.
Primary, Pulmonary Providers Endorse Lung CA Screening
THURSDAY, Oct. 12, 2017 (HealthDay News) — Primary care clinicians and pulmonologists endorse lung cancer screening (LCS), but there are limitations in their knowledge of screening components, according to a study published online Sept. 21 in the Annals of the American Thoracic Society.
Low-Cost Services a Major Player in Unnecessary Health Spending
THURSDAY, Oct. 12, 2017 (HealthDay News) — The costs associated with low-cost, low-value health services are nearly twice as high as those of high-cost, low-value services, according to a study published in the October issue of Health Affairs.
Medical License Questions Sway Doctors’ Mental Health Help
WEDNESDAY, Oct. 11, 2017 (HealthDay News) — Medical licensure application questions (MLAQs) regarding mental health contribute to physicians’ reluctance to seek help for mental health, according to a study published in the October issue of Mayo Clinic Proceedings.
Physician Salaries Appear to Be Flat or Declining
WEDNESDAY, Oct. 11, 2017 (HealthDay News) — Anecdotally, physician career coaches report that physician salaries are flat at best, according to an article published in Medical Economics.
New Tool IDs Mortality Risk After Bladder Cancer Surgery
WEDNESDAY, Oct. 11, 2017 (HealthDay News) — A new risk-stratification tool is able to estimate mortality in patients with urothelial carcinoma of the bladder (UCB) after cystectomy, according to a study published online Sept. 7 in Cancer.
HPV Vaccination After Lesion Treatment Is Likely Cost-Effective
WEDNESDAY, Oct. 11, 2017 (HealthDay News) — For HIV-infected men who have sex with men (MSM), adjuvant quadrivalent human papillomavirus vaccination (qHPV) after treatment of high-grade squamous intraepithelial lesions (HSIL) is likely to be cost-effective, according to a study published online Sept. 12 in Vaccine.
Guide Offers Doctors Tips for Choosing a Health System
TUESDAY, Oct. 10, 2017 (HealthDay News) — A guide has been developed to assist physicians considering joining a physician-led integrated health system, according to a report published by the American Medical Association (AMA).
Novel Metrics Suggested for Assessing EHR Use
TUESDAY, Oct. 10, 2017 (HealthDay News) — Novel metrics have been developed to assess electronic health record (EHR) use and are described in an opinion article published online Oct. 9 in the Annals of Internal Medicine.
Patient, Provider Interventions May Up Colonoscopy Rates
TUESDAY, Oct. 10, 2017 (HealthDay News) — For asymptomatic adults with positive fecal blood test results, patient navigators and provider reminders or performance data may help improve colonoscopy rates; however, current evidence about useful system-level interventions is insufficient, according to a review published online Oct. 9 in the Annals of Internal Medicine.
2016 Physician Quality Reporting System Reports Available
MONDAY, Oct. 9, 2017 (HealthDay News) — The 2016 Physician Quality Reporting System (PQRS) and the 2016 annual Quality and Resource Use reports have been released for individuals and group practices, according to a report published by the American Academy of Family Physicians.
Injured Patients Want More Info on Safety Improvement Efforts
MONDAY, Oct. 9, 2017 (HealthDay News) — Communication-and-resolution program (CRP) experiences are positive overall for a small majority of patients and families, but they report that hospitals rarely share information about preventing recurrences, according to a study published online Oct. 9 in JAMA Internal Medicine.
Negative Margins, Lymph Node Yields Predict Survival
MONDAY, Oct. 9, 2017 (HealthDay News) — Patients treated at hospitals that attain a high rate of negative margins and lymph node yields (LNY) of at least 18 have improved survival after surgery for head and neck squamous cell carcinomas (HNSCC), according to a study published online Oct. 5 in JAMA Otolaryngology — Head & Neck Surgery.
First Test to Detect Zika in Blood Donations Approved
FRIDAY, Oct. 6, 2017 (HealthDay News) — The cobas Zika test has been approved by the U.S. Food and Drug Administration — the first approved screening test to detect the Zika virus in blood donations.
Short-Lived Benefits for Abusive Supervisory Behavior
FRIDAY, Oct. 6, 2017 (HealthDay News) — Engaging in abusive supervisory behavior may be associated with short-term beneficial effects, but over longer periods of time, abusive supervisory behavior is negatively related to supervisors’ recovery level and engagement, according to a study published online Sept. 11 in the Academy of Management Journal.
Stronger Nocebo Effect When Inert Rx Labeled As Expensive
FRIDAY, Oct. 6, 2017 (HealthDay News) — Nocebo hyperalgesia is stronger when an inert treatment is labeled as being an expensive medication rather than a cheap one, according to a study published online Oct. 5 in Science.
Most Cancer Drugs Approved in Europe Show No Survival Benefit
FRIDAY, Oct. 6, 2017 (HealthDay News) — Most cancer drugs that enter the market in Europe have no evidence of benefit for survival or quality of life, according to a study published online Oct. 4 in BMJ.
Liver Cancer Remains a Major Public Health Burden Globally
FRIDAY, Oct. 6, 2017 (HealthDay News) — Causes of primary liver cancer differ widely among populations globally, but most cases can be prevented, according to a study published online Oct. 5 in JAMA Oncology.
21 Percent of Americans Report Experiencing a Medical Error
THURSDAY, Oct. 5, 2017 (HealthDay News) — More than one in five patients report having experienced a medical error, according to a survey released Sept. 28 by the Institute for Healthcare Improvement (IHI)/National Patient Safety Foundation Lucian Leape Institute and NORC at the University of Chicago.
Reasons Physicians Are Delaying Retirement Vary
THURSDAY, Oct. 5, 2017 (HealthDay News) — Physicians are delaying retirement, often because they feel they are providing a useful service to patients or because of concerns about social interaction in retirement, according to an article published online Sept. 25 in Medical Economics.
PFS Up With Obinutuzumab-Based Tx in Follicular Lymphoma
THURSDAY, Oct. 5, 2017 (HealthDay News) — For patients with follicular lymphoma, obinutuzumab-based immunochemotherapy is associated with longer progression-free survival than rituximab-based therapy, according to a study published online Oct. 4 in the New England Journal of Medicine.
Pay Inequality, Work-Life Balance Top Concerns for Female Docs
WEDNESDAY, Oct. 4, 2017 (HealthDay News) — Many female physicians report feeling disadvantaged when negotiating contracts and feel that they are assessed for promotion using different criteria than those used for men, according to a report published by the American Medical Association (AMA).
Provider Advice Impacts Breast Cancer Prevention Decisions
WEDNESDAY, Oct. 4, 2017 (HealthDay News) — For patients at high risk for breast cancer, health care provider (HCP) recommendation is the most important factor for deciding whether to use selective estrogen receptor modulators (SERMs), according to a study published online Oct. 4 in Cancer Prevention Research.
Insurance Type Linked to Surgery Delay in Melanoma
WEDNESDAY, Oct. 4, 2017 (HealthDay News) — Patients diagnosed with melanoma are more likely to have treatment delays if they are nonwhite or on Medicaid, while delays are less likely for patients diagnosed or treated by a dermatologist, according to a study published online Oct. 4 in JAMA Dermatology.
Rate of Obesity-, Overweight-Related Cancers High in the U.S.
WEDNESDAY, Oct. 4, 2017 (HealthDay News) — The burden of overweight- and obesity-related cancer is high in the United States, and incidence has increased in some states and age groups, according to a study published online Oct. 3 in Morbidity and Mortality Weekly Report.
Anticoagulants With Other Drugs Raise Bleeding Risk in AF
WEDNESDAY, Oct. 4, 2017 (HealthDay News) — Nonvalvular atrial fibrillation (AF) patients who take non-vitamin K oral anticoagulants (NOACs) along with certain other medications are at increased risk for major bleeding, and antithrombotic medications are significantly associated with increased rates of hematuria-related complications in older adults, according to two studies published online Oct. 3 in the Journal of the American Medical Association.
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Increase in Number of Centers Doing Robotic Prostatectomy
WEDNESDAY, Oct. 4, 2017 (HealthDay News) — The number of centers performing robotic surgery for radical prostatectomy increased during 2010 to 2014, according to a study published online Oct. 3 in The Lancet Oncology.
Smoking Cessation Support Less Likely for Cancer Patients
WEDNESDAY, Oct. 4, 2017 (HealthDay News) — General practitioners are less likely to support cessation of smoking in patients with cancer than in those with coronary heart disease (CHD), according to a study published online Sept. 11 in the Annals of Family Medicine.
Scientists Support Genome Editing to Prevent Disease
WEDNESDAY, Oct. 4, 2017 (HealthDay News) — Many basic scientists and clinical researchers support somatic genome editing in adults for prevention of serious disease but not for human enhancement; they also believe the public should be consulted before any clinical application of germline gene editing proceeds, according to survey results published online Oct. 3 in Circulation: Cardiovascular Genetics.
Process Promising for On-Site Printing of Custom-Dosed Meds
WEDNESDAY, Oct. 4, 2017 (HealthDay News) — Small molecular medicines can be printed precisely using organic vapor jets, according to a study published online Sept. 27 in Nature Communications.
Overall Breast Cancer Incidence Up for Some in 2005-2014
TUESDAY, Oct. 3, 2017 (HealthDay News) — Overall breast cancer incidence rates increased among specific racial/ethnic groups from 2005 to 2014, although the overall death rates decreased from 1989 to 2015, according to a study published online Oct. 3 in CA: A Cancer Journal for Clinicians.
Communication Program Doesn’t Raise Hospital Liability Costs
TUESDAY, Oct. 3, 2017 (HealthDay News) — A communication-and-resolution program, in which hospitals and liability insurers communicate with patients when adverse events occur, does not lead to higher liability costs, according to a study published online Oct. 2 in Health Affairs.
Fewer Deaths Projected With Switch to Electronic Cigarettes
TUESDAY, Oct. 3, 2017 (HealthDay News) — Replacement of cigarettes with electronic cigarettes (e-cigarettes) is projected to result in fewer premature deaths, even under a pessimistic scenario, according to a study published online Oct. 2 in Tobacco Control.
Sodium-Glucose Cotransporter 2 Inhibitors Not Cancer Risk Factor
TUESDAY, Oct. 3, 2017 (HealthDay News) — Over the short term there is not a significantly increased overall cancer risk among individuals with type 2 diabetes using sodium-glucose cotransporter 2 (SGLT2) inhibitors, according to a study published in the October issue of Diabetologia.
Adding Surveillance to FIT Screening Cuts CRC Mortality
TUESDAY, Oct. 3, 2017 (HealthDay News) — Adding surveillance to fecal immunochemical test (FIT) screening reduces colorectal cancer (CRC) mortality and increases colonoscopy demand, according to a study published online Oct. 2 in the Annals of Internal Medicine.
Tattoo Pigment Hypersensitivity Can Mimic Lymphoma
TUESDAY, Oct. 3, 2017 (HealthDay News) — Tattoo pigment hypersensitivity causing widespread lymphadenopathy has been described in a case report published online Oct. 2 in the Annals of Internal Medicine.
Opioid Manufacturers to Provide Doctor Training
MONDAY, Oct. 2, 2017 (HealthDay News) — In an effort to halt the ongoing opioid addiction crisis, U.S. regulators are requiring manufacturers to provide extensive training to doctors, according to a report published by the Associated Press.
Legal Cannabis Use Common Among Cancer Patients
MONDAY, Oct. 2, 2017 (HealthDay News) — In Washington state, where cannabis is legal, cancer patients have high rates of active use, and they report that legalization was an important factor in their decision to use, according to a study published online Sept. 25 in Cancer.
Hypermutated ctDNA Linked to Checkpoint Inhibitor Response
MONDAY, Oct. 2, 2017 (HealthDay News) — For patients with diverse malignancies, hypermutated blood-derived circulating tumor DNA (ctDNA) is associated with checkpoint inhibitor response, according to a study published online Oct. 2 in Clinical Cancer Research.
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